Crystal Structure of Human BPI and Two Bound Phospholipids at 2.4 Angstrom Resolution

PROCHECK: a program to check the stereochemical quality of protein structures

1993 • 23,689 citations

The CCP4 suite: programs for protein crystallography

1994 • 17,203 citations

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1991 • 14,222 citations

Free R value: a novel statistical quantity for assessing the accuracy of crystal structures

1992 • 3,863 citations

Verification of protein structures: Patterns of nonbonded atomic interactions

1993 • 3,673 citations

CLUSTAL: a package for performing multiple sequence alignment on a microcomputer

1988 • 3,446 citations

Assessment of protein models with three-dimensional profiles

1992 • 3,317 citations

Solvent-Accessible Surfaces of Proteins and Nucleic Acids

1983 • 2,685 citations

A graphics model building and refinement system for macromolecules

1978 • 1,858 citations

Structure and Function of Lipopolysaccharide Binding Protein

1990 • 1,689 citations

BIOCHEMISTRY OF ENDOTOXINS

1990 • 1,201 citations

PLASMA LIPID TRANSFER PROTEINS

1995 • 652 citations

A fast algorithm for rendering space-filling molecule pictures

1988 • 616 citations

Computation of molecular volume

1985 • 590 citations

Phosphocholine binding immunoglobulin Fab McPC603

1986 • 576 citations

Slow-cooling protocols for crystallographic refinement by simulated annealing

1990 • 530 citations

Lipid-Binding Proteins: A Family of Fatty Acid and Retinoid Transport Proteins

1994 • 483 citations

The covalent and three-dimensional structure of concanavalin A. IV. Atomic coordinates, hydrogen bonding, and quaternary structure.

1975 • 362 citations

Cloning and sequencing of human cholesteryl ester transfer protein cDNA

1987 • 354 citations

Structure of a dehydratase–isomerase from the bacterial pathway for biosynthesis of unsaturated fatty acids: two catalytic activities in one active site

1996 • 264 citations

Crystal structure of an endotoxin-neutralizing protein from the horseshoe crab, Limulus anti-LPS factor, at 1.5 A resolution.

1993 • 251 citations

Cloning of the cDNA of a Human Neutrophil Bactericidal Protein

1989 • 203 citations

Mammalian adipose tissue and muscle are major sources of lipid transfer protein mRNA

1991 • 191 citations

Endotoxin-neutralizing properties of the 25 kD N-terminal fragment and a newly isolated 30 kD C-terminal fragment of the 55-60 kD bactericidal/permeability-increasing protein of human neutrophils.

1991 • 182 citations

Complete cDNA encoding human phospholipid transfer protein from human endothelial cells.

1994 • 178 citations

A 25-kDa NH2-terminal fragment carries all the antibacterial activities of the human neutrophil 60-kDa bactericidal/permeability-increasing protein.

1987 • 158 citations

Functional expression of human and mouse plasma phospholipid transfer protein: effect of recombinant and plasma PLTP on HDL subspecies

1995 • 134 citations

Inhibition of Endotoxin-Induced Cytokine Release and Neutrophil Activation in Humans by Use of Recombinant Bactericidal/Permeability-Increasing Protein

1995 • 125 citations

Functional domains of recombinant bactericidal/permeability increasing protein (rBPI23).

1994 • 108 citations

Molecular cloning, characterization, and tissue distribution of rat lipopolysaccharide binding protein. Evidence for extrahepatic expression.

1994 • 104 citations

Analysis of topological and nontopological structural similarities in the PDB: New examples with old structures

1996 • 102 citations

Comparison of the structures of Cro and λ repressor proteins from bacteriophage λ

1983 • 91 citations

Cloning and mRNA tissue distribution of rabbit cholesteryl ester transfer protein.

1988 • 73 citations

Lipopolysaccharide (LPS) Neutralizing Peptides Reveal a Lipid A Binding Site of LPS Binding Protein

1995 • 73 citations

Expression and Characterization of Cysteine-Modified Variants of an Amino-Terminal Fragment of Bactericidal/Permeability-Increasing Protein

1996 • 69 citations

Biochemical Characterization of Recombinant Fusions of Lipopolysaccharide Binding Protein and Bactericidal/Permeability-increasing Protein

1997 • 61 citations

Identification of a sequence within the C-terminal 26 amino acids of cholesteryl ester transfer protein responsible for binding a neutralizing monoclonal antibody and necessary for neutral lipid transfer activity.

1992 • 61 citations

A 3D sequence-independent representation of the protein data bank

1995 • 58 citations

Molecular cloning, sequence, and expression of cynomolgus monkey cholesteryl ester transfer protein. Inverse correlation between hepatic cholesteryl ester transfer protein mRNA levels and plasma high density lipoprotein levels.

1991 • 58 citations

Prospects for use of recombinant BPI in the treatment of gram-negative bacterial infections.

1995 • 44 citations

Characterization of the structural elements in lipid A required for binding of a recombinant fragment of bactericidal/permeability-increasing protein rBPI23

1995 • 42 citations

Point Mutagenesis of Positively Charged Amino Acids of Cholesteryl Ester Transfer Protein: Conserved Residues within the Lipid Transfer/Lipopolysaccharide Binding Protein Gene Family Essential for Function

1995 • 30 citations

Nucleotide sequence of the bovine bactericidal permeability increasing protein (BPI)

1990 • 27 citations

Both N- and C-terminal regions of the bioactive N-terminal fragment of the neutrophil granule bactericidal/permeability-increasing protein are required for stability and function.

1996 • 24 citations