Hydroxyl free radical reactions with amino acids and proteins studied by electron spin resonance spectroscopy and spin-trapping

Ferrozine---a new spectrophotometric reagent for iron

1970 • 4,514 citations

The Biology of Oxygen Radicals

1978 • 3,361 citations

Fenton's reagent revisited

1975 • 2,778 citations

Free Radicals and Inflammation: Protection of Synovial Fluid by Superoxide Dismutase

1974 • 1,109 citations

Spectrophotometric determination of serum iron at the submicrogram level with a new reagent (ferrozine)

1971 • 767 citations

Respiratory chain linked H₂O₂ production in pigeon heart mitochondria

1971 • 544 citations

Do Mitochondria Produce Oxygen Radicals in vivo?

1978 • 530 citations

An Electron Spin Resonance Study of the Spin Adducts of OH and HO₂ Radicals with Nitrones in the Ultraviolet Photolysis of Aqueous Hydrogen Peroxide Solutions

1974 • 410 citations

Oxidative modification of glutamine synthetase. I. Inactivation is due to loss of one histidine residue.

1983 • 367 citations

Detection and identification of short-lived free radicals by electron spin resonance trapping techniques (spin trapping). Photolysis of organolead, -tin, and -mercury compounds

1969 • 291 citations

Evidence for the involvement of iron in the ADP-activatedperoxidation of lipids in microsomes and mitochondria

1964 • 267 citations

Oxidative modification of glutamine synthetase. II. Characterization of the ascorbate model system.

1983 • 266 citations

Spin trapping of some short-lived radicals by the nitroxide method

1971 • 201 citations

A membrane hypothesis of aging

1978 • 201 citations

Hydroxyl free radical formation from hydrogen peroxide by ferrous iron-nucleotide complexes

1983 • 176 citations

The role of membrane structure and function in cellular aging: A review

1979 • 150 citations

Spin trapping with .alpha.-pyridyl 1-oxide N-tert-butyl nitrones in aqueous solutions. A unique electron spin resonance spectrum for the hydroxyl radical adduct

1978 • 129 citations

Direct demonstration that ferrous ion complexes of di- and triphosphate nucleotides catalyze hydroxyl free radical formation from hydrogen peroxide

1983 • 125 citations

The Metabolic Fate of Mitochondrial Hydrogen Peroxide

1980 • 97 citations

Free radicals and carcinogenesis

1978 • 77 citations

Trapping of Free Radicals formed by γ-Irradiation of Organic Compounds

1968 • 76 citations

Formation of long-lived hydroxyl free radical adducts of proline and hydroxyproline in a fenton reaction

1984 • 75 citations

Spin trapping of peroxy radicals by phenyl N-(tert-butyl) nitrone and methyl N-duryl nitrone

1983 • 74 citations

Identification of free hydroxyl radicals in respiring rat heart mitochondria by spin trapping with the nitrone DMPO

1981 • 68 citations

Spin-trapping of free radicals formed during microsomal metabolism of ethylhydrazine and acetylhydrazine

1981 • 68 citations

E.S.R. of Spin-trapped Radicals in Aqueous Solutions of Amino Acids

1977 • 64 citations

Investigation of radical intermediates in organic reactions by use of nitroso compounds as scavengers the nitroxide method

1970 • 63 citations

On the role of cross-linking of cellular proteins in aging

1980 • 62 citations

Centrophenoxine increases the rates of total and mRNA synthesis in the brain cortex of old rats: An explanation of its action in terms of the membrane hypothesis of aging

1984 • 57 citations

SPIN TRAPPING OF FREE RADICALS PRODUCED FROM NITROSOAMINE CARCINOGENS

1978 • 56 citations

Hydroxyl free-radical spin-adduct in rat brain synaptosomes Observations on the reduction of the nitroxide

1983 • 55 citations

Spin trapping azidyl (N₃•), cyanatyl (OCN•), cyanyl (•CN) radicals, and chlorine atom (Cl•)

1980 • 47 citations

E.S.R. of Spin-trapped Radicals in Gamma-irradiated Aqueous Solutions of Nucleic Acids and Their Constituents

1976 • 44 citations

Electron spin resonance study of spin-trapped azide radicals in aqueous solutions

1980 • 43 citations

Radical yields in irradiated methanol and ethanol. An electron spin resonance and spin trapping method

1976 • 42 citations

The Detection of Alkoxy and Other Radicals in the Gamma Radiolysis of Alcohols by an Electron Spin Resonance and Spin Trapping Method

1974 • 42 citations

An E.S.R. and Spin-trapping Study of the Reactions of the ṠO₄⁻Radical with Protein and Nucleic Acid Constituents

1978 • 41 citations

Trapping of radicals formed in the photochemical reaction between hydrogen peroxide and some pyrimidine bases, nucleosides, nucleotides, and yeast nucleic acid

1973 • 38 citations

An estimate of the rate of spin trapping of methoxy radicals by 2-methyl-2-nitrosopropane (tert-nitrosobutane)

1977 • 35 citations

Photochemical synthesis. 58. Thione photochemistry. Photoreduction of adamantanethione

1975 • 32 citations

E.S.R. of Spin-trapped Radicals in Aqueous Solutions of Amino Acids

1977 • 31 citations

Uptake of Iron from Transferrin by Isolated Rat‐Liver Mitochondria Mediated by Phosphate Compounds

1980 • 29 citations

Studies on spin-trapped radicals in .gamma.-irradiated aqueous solutions of L-alanylglycine and L-alanyl-L-alanine by high-performance liquid chromatography and ESR spectroscopy

1982 • 26 citations

Spin trapping of adsorbed hydrogen

1979 • 22 citations

Differential effects of metal‐binding agents on the uptake of iron from transferrin by isolated rat liver mitochondria

1978 • 22 citations

Nucleotide‐Iron Complexes and Lipid Peroxidation: Mechanisms and Biological Significance

1981 • 21 citations

SPIN TRAPPING OF THE SHORT-LIVED RADICALS FORMED IN γ-IRRADIATED AQUEOUS SOLUTIONS OF DIPEPTIDES AND NUCLEIC BASES

1975 • 19 citations

ESR of Spin-Trapped Radicals in Aqueous Solutions of Dihydropyrimidine Bases

1978 • 19 citations

ESR STUDIES OF THE SHORT-LIVED ORGANIC RADICALS FORMED IN γ-IRRADIATED AQUEOUS SOLUTIONS. SPIN TRAPPING WITH 2-METHYL-2-NITROSOPROPANE

1974 • 18 citations

Hydrated Electron-initiated Main-chain Scission in Peptides

1978 • 16 citations

The Application of the Spin Trap, Phenylt-Butyl Nitrone, to the Study of the γ-Radiolysis of Cyclohexane

1977 • 15 citations

E.S.R. of Spin-trapped Radicals in γ-irradiated Polycrystalline Amino Acids. Chromatographic Separation of Radicals

1982 • 11 citations