Characterization of glial filament-cytoskeletal interactions in human astrocytomas: An immuno-ultrastructural analysis

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells

1991 • 1,685 citations

INTERMEDIATE FILAMENTS: Structure, Dynamics, Function and Disease

1994 • 1,408 citations

An acidic protein isolated from fibrous astrocytes

1971 • 1,192 citations

CD44 and Its Interaction with Extracellular Matrix

1993 • 1,082 citations

ERM family members as molecular linkers between the cell surface glycoprotein CD44 and actin-based cytoskeletons.

1994 • 790 citations

Immunoperoxidase localization of glial fibrillary acidic protein in radial glial cells and astrocytes of the developing rhesus monkey brain

1980 • 703 citations

GFAP Is Necessary for the Integrity of CNS White Matter Architecture and Long-Term Maintenance of Myelination

1996 • 521 citations

Heterogeneity of Genotypic and Phenotypic Characteristics of Fifteen Permanent Cell Lines Derived from Human Gliomas

1981 • 487 citations

The function of intermediate filaments in cell shape and cytoskeletal integrity.

1996 • 373 citations

Interaction between CD44 and hyaluronate is directly implicated in the regulation of tumor development.

1994 • 346 citations

CD44H regulates tumor cell migration on hyaluronate-coated substrate.

1992 • 334 citations

Mice lacking glial fibrillary acidic protein display astrocytes devoid of intermediate filaments but develop and reproduce normally.

1995 • 334 citations

Contribution of immunohistochemistry to diagnostic problems of human cerebral tumors.

1978 • 318 citations

Distinct effects of two CD44 isoforms on tumor growth in vivo.

1991 • 315 citations

A new in vitro assay for quantitating tumor cell invasion.

1989 • 297 citations

An Essential Cytoskeletal Linker Protein Connecting Actin Microfilaments to Intermediate Filaments

1996 • 297 citations

Selective suppression of CD44 in keratinocytes of mice bearing an antisense CD44 transgene driven by a tissue-specific promoter disrupts hyaluronate metabolism in the skin and impairs keratinocyte proliferation.

1997 • 270 citations

Mice devoid of the glial fibrillary acidic protein develop normally and are susceptible to scrapie prions

1995 • 258 citations

The role of glial fibrillary acidic protein in the diagnosis of central nervous system tumors

1978 • 240 citations

CD44 mediates human glioma cell adhesion and invasion in vitro.

1994 • 217 citations

Textbook of neuropathology

1986 • 215 citations

Determinants of human astrocytoma migration.

1994 • 204 citations

DETERMINANTS FOR THE ESTABLISHMENT OF PERMANENT TISSUE CULTURE LINES FROM HUMAN GLIOMAS

1973 • 189 citations

AP-1-Mediated Invasion Requires Increased Expression of the Hyaluronan Receptor CD44

1997 • 170 citations

Chronic hepatitis, hepatocyte fragility, and increased soluble phosphoglycokeratins in transgenic mice expressing a keratin 18 conserved arginine mutant.

1995 • 161 citations

Glial Fibrillary Acidic Protein: Dynamic Property and Regulation by Phosphorylation

1994 • 156 citations

Role of glial filaments in cells and tumors of glial origin: a review

1997 • 156 citations

Phosphorylation sites linked to glial filament disassembly in vitro locate in a non-alpha-helical head domain.

1990 • 155 citations

The Application of filial Fibrillary Acidic (GFA) Protein Immunohistochemistry in Neurooncology

1980 • 154 citations

Formation and growth of multicellular spheroids of human origin

1983 • 154 citations

Properties of human malignant glioma cells in vitro.

1978 • 149 citations

Structure and Transcriptional Regulation of the GFAP Gene

1994 • 146 citations

The presence or absence of a vimentin-type intermediate filament network affects the shape of the nucleus in human SW-13 cells

1994 • 139 citations

GFA and S 100 Protein Levels as an Index for Malignancy in Human Gliomas and Neurinomas2

1979 • 123 citations

Immunolocalization of the intermediate filament-associated protein plectin at focal contacts and actin stress fibers.

1992 • 122 citations

Expression of plectin mutant cDNA in cultured cells indicates a role of COOH-terminal domain in intermediate filament association.

1993 • 117 citations

Effects of antisense glial fibrillary acidic protein complementary DNA on the growth, invasion, and adhesion of human astrocytoma cells.

1994 • 102 citations

Two different protein kinases act on a different time schedule as glial filament kinases during mitosis.

1992 • 102 citations

An Ultrastructural and Immunocytochemical Analysis of Leptomeningeal and Meningioma Cultures

1986 • 101 citations

Plectin: General Overview and Appraisal of its potential Role as a Subunit Protein of the Cytomatri

1989 • 95 citations

Firing variability in cat association cortex during sleep and wakefulness

1970 • 95 citations

Suppression of CD44 expression decreases migration and invasion of human glioma cells

1996 • 85 citations

Variant CD44 adhesion molecules are expressed in human brain metastases but not in glioblastomas.

1993 • 84 citations

Distribution of plectin, an intermediate filament‐associated protein, in the adult rat central nervous system

1994 • 77 citations

Hyaluronate binding and CD44 expression in human glioblastoma cells and astrocytes

1992 • 76 citations

The relationship of glial fibrillary acidic protein to the shape, motility, and differentiation of human astrocytoma cells

1982 • 76 citations

Dynamic organisation of intermediate filaments and associated proteins during the cell cycle

1997 • 72 citations

Immunohistochemistry of the Glial Fibrillary Acidic Protein: Basic and Applied Considerations

1994 • 71 citations

Expression of variant CD44 epitopes in human astrocytic brain tumors

1995 • 59 citations

Tumor-specific membrane antigens in established cell lines from gliomas

1974 • 56 citations

Involvement of CD44 and its variant isoforms in membrane-cytoskeleton interaction, cell adhesion and tumor metastasis

1995 • 56 citations

Transfection of an Invasive Human Astrocytoma Cell Line with a TIMP-1 cDNA

1996 • 50 citations

Identification of Phosphorylation Sites on Glial Fibrillary Acidic Protein for cdc2 Kinase and Ca2+-Calmodulin-Dependent Protein Kinase II1

1994 • 47 citations

Expression of CD44 splice variants in human primary brain tumors

1995 • 43 citations

EXPRESSION OF TIMP-1, TIMP-2, 72-KDA AND 92-KDA TYPE-IV COLLAGENASE TRANSCRIPTS IN HUMAN ASTROCYTOMA CELL-LINES - CORRELATION WITH ASTROCYTOMA CELL INVASIVENESS

1995 • 41 citations

Localization of basic proteins in human myelin

1993 • 40 citations

Glial fibrillary acidic protein and induced differentiation of glia in vitro

1982 • 32 citations

Expression of an epidermal keratin protein in liver of transgenic mice causes structural and functional abnormalities.

1995 • 32 citations

Localization of CD44 (P80) on the external surface of a human astrocytoma cell

1991 • 23 citations

Expression of the CD44 adhesion molecule in tumours of the central and peripheral nervous system

1995 • 21 citations

Transient arrest of 3T3 cells in mitosis and inhibition of nuclear lamin reassembly around chromatin induced by anti-vimentin antibodies.

1993 • 17 citations