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Activation of proto-oncogenes in human leukemias

Data up to Jan 2025

Published1985
Citations11
References44

Total Citations Per Year

Abstract

References (44)

A minute chromosome in human chronic granulocytic leukemia

1960 • 2,329 citations

Amplification of N- myc in Untreated Human Neuroblastomas Correlates with Advanced Disease Stage

1984 • 2,248 citations

CELLULAR ONCOGENES AND RETROVIRUSES

1983 • 1,671 citations

Philadelphia chromosomal breakpoints are clustered within a limited region, bcr, on chromosome 22

1984 • 1,644 citations

A cellular oncogene is translocated to the Philadelphia chromosome in chronic myelocytic leukaemia

1982 • 1,385 citations

Cellular Oncogenes and Multistep Carcinogenesis

1983 • 1,154 citations

The Chromosomal Basis of Human Neoplasia

1983 • 1,121 citations

An alteration of the human c-abl protein in K562 leukemia cells unmasks associated tyrosine kinase activity

1984 • 913 citations

Expression of Cellular Oncogenes in Human Malignancies

1984 • 840 citations

Translocation of c-abl oncogene correlates with the presence of a Philadelphia chromosome in chronic myelocytic leukaemia

1983 • 743 citations

Translocations Among Antibody Genes in Human Cancer

1983 • 736 citations

Decreased expression of N-myc precedes retinoic acid-induced morphological differentiation of human neuroblastoma

1985 • 644 citations

onc gene amplification in promyelocytic leukaemia cell line HL-60 and primary leukaemic cells of the same patient

1982 • 638 citations

Intrinsic GTPase activity distinguishes normal and oncogenic ras p21 molecules.

1984 • 607 citations

Amino-acid substitutions at codon 13 of the N-ras oncogene in human acute myeloid leukaemia

1985 • 372 citations

Close link between reduction of c-myc expression by interferon and G0/G1 arrest

1985 • 358 citations

Molecular Basis of Human B Cell Neoplasia

1985 • 316 citations

Unique allelic restriction fragments of the human Ha-ras locus in leukocyte and tumour DNAs of cancer patients

1985 • 283 citations

Molecular basis of human B cell neoplasia

1985 • 244 citations

An 8-kilobase abl RNA transcript in chronic myelogenous leukemia.

1984 • 210 citations

Altered Transcription of the c- abl Oncogene in K-562 and Other Chronic Myelogenous Leukemia Cells

1984 • 209 citations

Transforming genes of human hematopoietic tumors: frequent detection of ras-related oncogenes whose activation appears to be independent of tumor phenotype.

1983 • 172 citations

Is the chromosomal region 9q34 always involved in variants of the Ph1 translocation?

1984 • 158 citations

Transient reversion of ras oncogene-induced cell transformation by antibodies specific for amino acid 12 of ras protein

1985 • 152 citations

C-abl and bcr are rearranged in a Ph1-negative CML patient.

1985 • 144 citations

Anti-sense RNA as a molecular tool for ] genetic analysis

1985 • 120 citations

Cellular transforming genes and oncogenesis

1984 • 111 citations

Metallothionein gene cluster is split by chromosome 16 rearrangements in myelomonocytic leukaemia

1985 • 98 citations

Recent Results in Cancer Research

1979 • 94 citations

GENOMIC ALTERATIONS INVOLVING THE C-MYC PROTO-ONCOGENE LOCUS DURING THE EVOLUTION OF A CASE OF CHRONIC GRANULOCYTIC LEUKAEMIA

1984 • 91 citations

Oncogene expression in human leukemia

1984 • 87 citations

Expression of Cellular Oncogenes

1984 • 82 citations

Translocation of c-abl to “Masked” Ph in chronic myeloid leukemia

1985 • 80 citations

Oncogenes and proto-oncogenes: How do they differ?

1984 • 78 citations

The cytogenetics of chronic myelocytic leukemia (CML): Chronic phase and blastic crisis

1980 • 53 citations

Roles of growth factor activities in oncogenesis

1984 • 50 citations

Activation of an N-ras gene in acute myeloblastic leukemia through somatic mutation in the first exon.

1985 • 50 citations

Current Topics in Microbiology and Immunology Vol. 48

1970 • 50 citations

Roles of growth factor activities in oncogenesis

1984 • 44 citations

Expression of oncogenes in human leukemias.

1984 • 37 citations

Oncogenes: Implications for the Diagnosis and Treatment of Cancer

1984 • 33 citations

Translocation and rearrangement of c-myc into immunoglobulin alpha heavy chain locus in primary cells from acute lymphocytic leukemia.

1984 • 24 citations

Cytogenetics in Leukemia: Implications for Pathogenesis and Prognosis

1984 • 6 citations

Molekulargenetische Aspekte der chronisch myeloischen Leukämie

2008 • 1 citations

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