Increased expression of heparanase in puromycin aminonucleoside nephrosis

Growth factors in the extracellular matrix

1997 • 879 citations

Mammalian heparanase: Gene cloning, expression and function in tumor progression and metastasis

1999 • 788 citations

Cloning of mammalian heparanase, an important enzyme in tumor invasion and metastasis

1999 • 516 citations

Identification of sulfated oligosaccharide-based inhibitors of tumor growth and metastasis using novel in vitro assays for angiogenesis and heparanase activity.

1999 • 398 citations

Renal basement membrane components

1999 • 347 citations

Expression of heparanase by platelets and circulating cells of the immune system: possible involvement in diapedesis and extravasation.

1992 • 301 citations

Human Heparanase

1999 • 297 citations

An ultrastructural study of the mechanisms of proteinuria in aminonucleoside nephrosis

1975 • 296 citations

[16] Solubilization of functional membrane proteins

1984 • 272 citations

Extracellular matrix-resident growth factors and enzymes: possible involvement in tumor metastasis and angiogenesis

1990 • 253 citations

Degradation of heparan sulfate in the subendothelial extracellular matrix by a readily released heparanase from human neutrophils. Possible role in invasion through basement membranes.

1985 • 210 citations

Effect of Diabetes on the Glycosaminoglycan Component of the Human Glomerular Basement Membrane

1982 • 203 citations

Processing of the Human Heparanase Precursor and Evidence That the Active Enzyme Is a Heterodimer

1999 • 200 citations

Cloning and Functional Expression of a Human Heparanase Gene

1999 • 199 citations

Human platelet heparanase: purification, characterization and catalytic activity

1998 • 191 citations

Glomerular heparan sulfate alterations: Mechanisms and relevance for proteinuria

2000 • 184 citations

Reactive oxygen species and neutrophil respiratory burst cytochrome b558 are produced by kidney glomerular cells in passive Heymann nephritis.

1993 • 142 citations

The human neutrophil serine proteinases, elastase and cathepsin G, can mediate glomerular injury in vivo.

1988 • 138 citations

Autoantibodies to myeloperoxidase aggravate mild anti-glomerular-basement-membrane-mediated glomerular injury in the rat.

1996 • 114 citations

Ultrastructural changes of extracellular matrices in diabetic nephropathy revealed by high resolution scanning and immunoelectron microscopy.

1993 • 88 citations

Glomerular epithelial abnormalities associated with the onset of proteinuria in aminonucleoside nephrosis.

1987 • 84 citations

Stable cell line of T-SV40 immortalized human glomerular visceral epithelial cells

1991 • 79 citations

Degradation of sulfated proteoglycans in the subendothelial extracellular matrix by human platelet heparitinase.

1984 • 78 citations

Identification of ezrin as an 81-kDa tyrosine-phosphorylated protein in T cells.

1992 • 77 citations

Monoclonal antibodies against the protein core and glycosaminoglycan side chain of glomerular basement membrane heparan sulfate proteoglycan: characterization and immunohistological application in human tissues.

1994 • 65 citations

Treatment of central nervous system inflammation with inhibitors of basement membrane degradation

1998 • 52 citations

Significance of anti-nuclear and anti-extracellular matrix autoantibodies for albuminuria in murine lupus nephritis; a longitudinal study on plasma and glomerular eluates in MRL/l mice

1996 • 49 citations

Decrease of heparan sulfate staining in the glomerular basement membrane in murine lupus nephritis.

1995 • 47 citations

Evidence that platelet and tumour heparanases are similar enzymes

1999 • 35 citations

Adriamycin Affects Glomerular Renal Function: Evidence for the Involvement of Oxygen Radicals

1989 • 33 citations

Elastase, but not proteinase 3 (PR3), induces proteinuria associated with loss of glomerular basement membrane heparan sulphate after in vivo renal perfusion in rats

1996 • 31 citations

Differential Effects of Polysulfated Polysaccharide on Experimental Encephalomyelitis, Proliferation of Autoimmune T Cells, and Inhibition of Heparanase Activity

1995 • 29 citations

Thrombin enhances degradation of heparan sulfate in the extracellular matrix by tumor cell heparanase

1992 • 13 citations