Localized chemical hyperreactivity in supercoiled DNA. Evidence for base unpairing in sequences that induce low-salt cruciform extrusion

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

A new pair of M13 vectors for selecting either DNA strand of double-digest restriction fragments

1982 • 3,041 citations

Nonchromosomal Antibiotic Resistance in Bacteria: Genetic Transformation of Escherichia coli by R-Factor DNA

1972 • 2,842 citations

Nonintercalating DNA-binding ligands: Specificity of the interaction and their use as tools in biophysical, biochemical and biological investigations of the genetic material

1986 • 765 citations

A bifurcated hydrogen-bonded conformation in the d(A.T) base pairs of the DNA dodecamer d(CGCAAATTTGCG) and its complex with distamycin.

1987 • 671 citations

Determination of the number of superhelical turns in simian virus 40 DNA by gel electrophoresis.

1975 • 538 citations

Nature of the open state in long polynucleotide double helices: possibility of soliton excitations.

1980 • 464 citations

Binding of an antitumor drug to DNA

1985 • 423 citations

A single mode of DNA base-pair opening drives imino proton exchange

1987 • 380 citations

Effect of Growth Conditions on the Formation of the Relaxation Complex of Supercoiled ColE1 Deoxyribonucleic Acid and Protein in Escherichia coli

1972 • 351 citations

Reaction of sodium bisulfite with uracil, cytosine, and their derivatives

1970 • 344 citations

Polynucleotide kinase exchange reaction: quantitave assay for restriction endonuclease-generated 5'-phosphoroyl termini in DNA.

1977 • 289 citations

Chemical probes of DNA conformation: detection of Z-DNA at nucleotide resolution

1985 • 286 citations

Reactions of Uracil and Cytosine Derivatives with Sodium Bisulfite

1970 • 273 citations

Bisulfite Modification of Nucleic Acids and their Constituents

1976 • 214 citations

Interaction of the oligopeptide antibiotics netropsin and distamycin a with nucleic acids

1971 • 170 citations

Nucleic Acid Reactivity and Conformation

1973 • 170 citations

Transmission of stability (telestability) in deoxyribonucleic acid. Physical and enzymatic studies on the duplex block polymer d(C15A15) - d(T15G15).

1975 • 134 citations

Netropsin, a New Antibiotic Produced by a Streptomyces

1951 • 133 citations

Determination of Base Sequence in Nucleic Acids with the Electron Microscope. V. The Thymine-Specific Reactions of Osmium Tetroxide with Deoxyribonucleic Acid and Its Components^*

1966 • 127 citations

The N-Terminal Amino-Acid Sequences of DNA Polymerase I from Escherichia coli and of the Large and the Small Fragments Obtained by a Limited Proteolysis

1974 • 122 citations

Escherichia coli K-12 mutants deficient in uracil-DNA glycosylase

1978 • 120 citations

(A-T)_ntracts embedded in random sequence DNA — formation of a structure which is chemically reactive and torsionally deformable

1986 • 113 citations

Detection of an altered DNA conformation at specific sites in chromatin and supercoiled DNA.

1983 • 109 citations

A dominant influence of flanking sequences on a local structural transition in DNA

1986 • 104 citations

The kinetic properties of cruciform extrusion are determined by DNA base-sequence

1985 • 95 citations

The reaction of glyoxal with nucleic acid components III. Kinetics of the reaction with monomers

1971 • 88 citations

Altered DNA conformations detected by mung bean nuclease occur in promoter and terminator regions of supercoiled pBR322 DNA

1985 • 83 citations

Conversion of Exposed Cytidine Residues to Uridine Residues in Escherichia coli Formylmethionine Transfer Ribonucleic Acid

1972 • 82 citations

Influence of cation size and charge on the extrusion of a salt-dependent cruciform

1987 • 78 citations

Fluorescent Modification of Adenosine 3′,5′-Monophosphate: Spectroscopic Properties and Activity in Enzyme Systems

1972 • 76 citations

Structural perturbation in supercoiled DNA: hypersensitivity to modification by a single-strand-selective chemical reagent conferred by inverted repeat sequences

1983 • 73 citations

Thermodynamics of the ColE1 cruciform

1984 • 72 citations

Osmium-labeled polynucleotides. The reaction of osmium tetroxide with deoxyribonucleic acid and synthetic polynucleotides in the presence of tertiary nitrogen donor ligands

1977 • 60 citations

Osmium-induced alteration in DNA structure.

1984 • 59 citations

Recognition of the Structural Distortions at the Junctions Between B and Z Segments in Negatively Supercoiled DNA by Osmium Tetroxide

1985 • 58 citations

A two-state conformational equilibrium for alternating (A-T)n sequences in negatively supercoiled DNA

1987 • 52 citations

Osmium tetroxide: a new probe for site-specific distortions in supercoiled DNAs

1984 • 51 citations

Reaction conditions affect the specificity of bromoacetaidehyde as a probe for DNA cruciforms and B—Z junctions

1987 • 44 citations

A naphtho-tri-t-butyltrisdehydro[16]annulene and related compounds

1981 • 44 citations

Kinetics of Cruciform Formation and Stability of Cruciform Structure in Superhelical DNA

1984 • 43 citations

Aspects of specific protein-DNA interaction; multi-mode binding of the oligopeptide antibiotic netropsin to (A·T)-rich DNA segments

1979 • 42 citations

Modification of adenine and cytosine derivatives with bromoacetaldehyde.

1980 • 41 citations

Long range structural communication between sequences in supercoiled DNA. Sequence dependence of contextual influence on cruciform extrusion mechanism.

1988 • 34 citations

Helix stability and the mechanism of cruciform extrusion in supercoiled DNA molecules

1988 • 26 citations