Characterization of a guanine nucleotide-releasing factor and a GTPase-activating protein that are specific for the ras-related protein p25rab3A.

Determination of molecular weights and frictional ratios of proteins in impure systems by use of gel filtration and density gradient centrifugation. Application to crude preparations of sulfite and hydroxylamine reductases

1966 • 2,239 citations

A Cytoplasmic Protein Stimulates Normal N- ras p21 GTPase, But Does Not Affect Oncogenic Mutants

1987 • 1,197 citations

The GAP-related domain of the neurofibromatosis type 1 gene product interacts with ras p21

1990 • 984 citations

The Cellular Functions of Small GTP-Binding Proteins

1990 • 881 citations

The NF1 locus encodes a protein functionally related to mammalian GAP and yeast IRA proteins

1990 • 834 citations

The catalytic domain of the neurofibromatosis type 1 gene product stimulates ras GTPase and complements ira mutants of S. cerevisiae

1990 • 684 citations

ras GTPase activating protein: Signal transmitter and signal terminator

1989 • 621 citations

rab3 is a small GTP-binding protein exclusively localized to synaptic vesicles.

1990 • 486 citations

A small GTP-binding protein dissociates from synaptic vesicles during exocytosis

1991 • 441 citations

Four additional members of the ras gene superfamily isolated by an oligonucleotide strategy: molecular cloning of YPT-related cDNAs from a rat brain library.

1987 • 403 citations

Mutational analysis of SEC4 suggests a cyclical mechanism for the regulation of vesicular traffic.

1989 • 314 citations

Purification and characterization from bovine brain cytosol of a protein that inhibits the dissociation of GDP from and the subsequent binding of GTP to smg p25A, a ras p21-like GTP-binding protein.

1990 • 305 citations

Regulation of reversible binding of smg p25A, a ras p21-like GTP-binding protein, to synaptic plasma membranes and vesicles by its specific regulatory protein, GDP dissociation inhibitor.

1990 • 268 citations

Identification of distinct cytoplasmic targets for ras/R-ras and rho regulatory proteins

1989 • 258 citations

A Cytosolic Protein Catalyzes the Release of GDP from p21 ^ras

1990 • 231 citations

The effect of Mg2+ on the guanine nucleotide exchange rate of p21N-ras.

1986 • 203 citations

Association of the GTP-binding protein Rab3A with bovine adrenal chromaffin granules.

1990 • 195 citations

ras and GAP—Who's controlling whom?

1990 • 185 citations

Purification and characterization from bovine brain cytosol of proteins that regulate the GDP/GTP exchange reaction of smg p21s, ras p21-like GTP-binding proteins.

1990 • 154 citations

A carboxyl-terminal cysteine residue is required for palmitic acid binding and biological activity of the ras-related yeast YPT1 protein.

1988 • 138 citations

Purification and Characterization from Bovine Brain Cytosol of Two Gtpase-Activating Proteins Specific for smg p21, a GTP-binding Protein Having the Same Effector Domain as c-ras p21s

1989 • 120 citations

A novel membrane factor stimulates guanine nucleotide exchange reaction of ras proteins

1990 • 119 citations

Regulation of the GTPase activity of the ras-like protein p25rab3A. Evidence for a rab3A-specific GAP.

1991 • 89 citations

Role of the C-terminal region of smg p25A in its interaction with membranes and the GDP/GTP exchange protein.

1991 • 87 citations

Tissue distribution of smg p25A, a ras p21-like GTP-binding protein, studied by use of a specific monoclonal antibody

1989 • 84 citations

Tissue-specific expression of a novel GTP-binding protein (smg p25A) mRNA and its increase by nerve growth factor and cyclic AMP in rat pheochromocytoma PC-12 cells

1989 • 79 citations

Purification of a factor capable of stimulating the guanine nucleotide exchange reaction of ras proteins and its effect on ras-related small molecular mass G proteins.

1990 • 73 citations

The ras-like protein p25rab3A is partially cytosolic and is expressed only in neural tissue.

1989 • 39 citations

Evidence for Multiple, ras-like, Guanine Nucleotide-binding Proteins in Swiss 3T3 Plasma Membranes

1989 • 19 citations

Role of the C-Terminal Region of smg p25A in Its Interaction with Membranes and the GDP/GTP Exchange Protein

1991 • 16 citations

The ras-Like Protein p25^rab3A Is Partially Cytosolic and Is Expressed Only in Neural Tissue

1989 • 7 citations

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