Structural requirements for biological activity of glucagon‐like peptide‐I

THE PREPARATION OF 131I-LABELLED HUMAN GROWTH HORMONE OF HIGH SPECIFIC RADIOACTIVITY

1963 • 10,322 citations

Solid Phase Peptide Synthesis. I. The Synthesis of a Tetrapeptide

1963 • 7,266 citations

Quantitative monitoring of solid-phase peptide synthesis by the ninhydrin reaction

1981 • 1,044 citations

Insulinotropin: glucagon-like peptide I (7-37) co-encoded in the glucagon gene is a potent stimulator of insulin release in the perfused rat pancreas.

1987 • 814 citations

Preproglucagon gene expression in pancreas and intestine diversifies at the level of post-translational processing.

1986 • 686 citations

Hamster preproglucagon contains the sequence of glucagon and two related peptides

1983 • 602 citations

Continuous, clonal, insulin- and somatostatin-secreting cell lines established from a transplantable rat islet cell tumor.

1980 • 496 citations

Glucagon-Like Peptides GLP-1 and GLP-2, Predicted Products of the Glucagon Gene, Are Secreted Separately from Pig Small Intestine but Not Pancreas*

1986 • 475 citations

Insulinotropic Action of Glucagonlike Peptide-I-(7–37) in Diabetic and Nondiabetic Subjects

1992 • 282 citations

Glucagonlike Peptide I (7–37) Actions on Endocrine Pancreas

1989 • 254 citations

Mammalian pancreatic preproglucagon contains three glucagon-related peptides.

1983 • 218 citations

Glucagon gene sequence. Four of six exons encode separate functional domains of rat pre-proglucagon.

1984 • 206 citations

Pre-Proglucagon Messenger Ribonucleic Acid: Nucleotide and Encoded Amino Acid Sequences of the Rat Pancreatic Complementary Deoxyribonucleic Acid*

1984 • 147 citations

Anglerfish islet pre-proglucagon II. Nucleotide and corresponding amino acid sequence of the cDNA.

1983 • 137 citations

Glucagon-Like Peptide-I Analogs: Effects on Insulin Secretion and Adenosine 3′,5′-Monophosphate Formation*

1990 • 106 citations

Isolation and structures of coho salmon (Oncorhynchus kisutch) glucagon and glucagon-like peptide

1986 • 87 citations

Isolation and structures of glucagon and glucagon-like peptide from catfish pancreas.

1985 • 80 citations

Weak acid‐catalyzed pyrrolidone carboxylic acid formation from glutamine during solid phase peptide synthesis

1982 • 77 citations

Mutations in the guinea pig preproglucagon gene are restricted to a specific portion of the prohormone sequence

1986 • 65 citations

Cloning of Complementary DNAs Encoding Islet Amyloid Polypeptide, Insulin, and Glucagon Precursors from a New World Rodent, the Degu,Octodon degus

1990 • 65 citations

Absence of insulinotropic glucagon‐like peptide‐I(7–37) receptors on isolated rat liver hepatocytes

1991 • 57 citations

Nucleotide sequence determination of chicken glucagon precursor cDNA

1990 • 54 citations

Isolation and structure of the principal products of preproglucagon processing, including an amidated glucagon-like peptide.

1986 • 46 citations

Primary structures of three fragments of proglucagon from the pancreatic islets of the daddy Sculpin (Cottus scorpius)

1987 • 38 citations

An improved synthesis of crystalline mammalian glucagon

1984 • 36 citations

Pancreatic Proglucagon Processing: Isolation and Structures of Glucagon and Glucagon-Like Peptide from Gene I*

1988 • 21 citations

Isolation of lipoprotein A with hydrated density characteristic for low density lipoproteins

1972 • 13 citations

Improved deprotection in solid phase peptide synthesis: deprotection of Nⁱ-formyl-tryptophan to tryptophan in low concentrations of HF in Me₂S–p- thiocresol mixtures

1982 • 12 citations

Radiation workers: Health bias to recruitment?

1983 • 1 citations