T‐cell expansions in patients with multiple myeloma have a phenotype of cytotoxic T cells

A clinical staging system for multiple myeloma correlation of measured myeloma cell mass with presenting clinical features, response to treatment, and survival

1975 • 3,051 citations

Fas and Perforin Pathways as Major Mechanisms of T Cell-Mediated Cytotoxicity

1994 • 1,558 citations

Clonal populations of T cells in normal elderly humans: the T cell equivalent to "benign monoclonal gammapathy".

1994 • 788 citations

CD28- T lymphocytes. Antigenic and functional properties.

1993 • 403 citations

Shortened telomeres in clonally expanded CD28-CD8+ T cells imply a replicative history that is distinct from their CD28+CD8+ counterparts.

1996 • 378 citations

Expansion of cytotoxic CD8⁺ CD28⁻ T cells in healthy ageing people, including centenarians

1996 • 355 citations

Expanded CD4+ and CD8+ T cell clones in elderly humans.

1997 • 307 citations

Characterization of a phenotypically distinct subpopulation of Leu-2+ cells that suppresses T cell proliferative responses.

1983 • 251 citations

Morphologic and phenotypic features of the subpopulation of Leu-2+ cells that suppresses B cell differentiation.

1984 • 196 citations

Oligoclonal CD8+ T cells are preferentially expanded in the CD57+ subset.

1995 • 162 citations

CD8highCD57+ T lymphocytes in normal, healthy individuals are oligoclonal and respond to human cytomegalovirus.

1995 • 160 citations

B7-mediated costimulation and the immune response

1996 • 128 citations

Cell-mediated suppression of HIV-specific cytotoxic T lymphocytes.

1989 • 124 citations

T cell repertoire in patients with B chronic lymphocytic leukemia. Evidence for multiple in vivo T cell clonal expansions.

1994 • 114 citations

Persistence of T8+/HNK-1+ suppressor lymphocytes in the blood of long-term surviving patients after allogeneic bone marrow transplantation.

1986 • 105 citations

A soluble factor released by CD8+CD57+ lymphocytes from bone marrow transplanted patients inhibits cell-mediated cytolysis

1991 • 99 citations

Presence of clonal T cell populations in chronic B lymphocytic leukemia and smoldering myeloma.

1990 • 93 citations

Studies on the Pathogenesis of an Immune Defect in Multiple Myeloma

1977 • 92 citations

Cord blood T lymphocytes lack constitutive perforin expression in contrast to adult peripheral blood T lymphocytes

1995 • 88 citations

Increased cytolytic T lymphocyte activity and decreased B7 responsiveness are associated with CD28 down-regulation on CD8+ T cells from HIV-infected subjects

1995 • 87 citations

Clonal populations of CD4+ and CD8+ T cells in patients with multiple myeloma and paraproteinemia

1996 • 86 citations

A lectin‐binding soluble factor released by CD8⁺CD57⁺ lymphocytes from AIDS patients inhibits T cell cytotoxicity

1991 • 81 citations

The prognostic significance of T cell receptor β gene rearrangements and idiotype-reactive T cells in multiple myeloma

1997 • 79 citations

Multiple myeloma: increased circulating lymphocytes carrying plasma cell-associated antigens as an indicator of poor survival

1990 • 70 citations

Long-Term Depletion of Naive T Cells in Patients Treated for Hodgkin's Disease

1997 • 70 citations

Functional abnormalities of CD8+ T cells define a unique subset of patients with common variable immunodeficiency

1993 • 70 citations

T cell repertoire in patients with multiple myeloma and monoclonal gammopathy of undetermined significance: Clonal CD8⁺ T cell expansions are found preferentially in patients with a low tumor burden

1997 • 67 citations

The effect of cytomegalovirus infection on T lymphocytes after allogeneic bone marrow transplantation.

1985 • 66 citations

Activated idiotype-reactive cells in suppressor/cytotoxic subpopulations of monoclonal gammopathies: correlation with diagnosis and disease status

1988 • 66 citations

Idiotype‐specific T lymphocytes in monoclonal gammopathies: evidence for the presence of CD4⁺ and CD8⁺ subsets

1997 • 59 citations

CD8⁺/CD57⁺ cells and apoptosis suppress T‐cell functions in multiple myeloma

1998 • 59 citations

Increased percentage of cd3+, cd57+ lymphocytes in patients with rheumatoid arthritis. correlation with duration of disease

1993 • 58 citations

Persistent clonal excess and skewed T-cell repertoire in T cells from patients with hairy cell leukemia

1996 • 58 citations

Activated idiotype-reactive cells in suppressor/cytotoxic subpopulations of monoclonal gammopathies: correlation with diagnosis and disease status

1988 • 49 citations

Predominant T cell receptor V gene usage in patients with abnormal clones of B cells

1991 • 49 citations

IMMUNOREGULATORY MECHANISMS IN MULTIPLE MYELOMA

1997 • 38 citations

The human T cell antigen receptor repertoire: skewed use of Vβ gene families by CD8+ cells

1994 • 33 citations

Altered T cell Repertoire Usage in CD4 and CD8 Subsets of Multiple Myeloma Patients, a Study of the Eastern Cooperative Oncology Group (E9487)

1999 • 32 citations

Two-color immunofluorescence and flow cytometry analysis of lymphocytes in long-term renal allotransplant recipients: identification of a major Leu-7+/Leu-3+ subpopulation.

1985 • 30 citations

In vitro inhibition of normal human hematopoiesis by marrow CD3+, CD8+, HLA-DR+, HNK1+ lymphocytes

1988 • 28 citations

The T cell receptor repertoire of CD8+CD28− T lymphocytes is dominated by expanded clones that persist over time

1999 • 20 citations

Peripheral Blood Lymphocyte Surface Antigen Expression and Prognosis in Myeloma: Australian Leukaemia Study Group Study

1994 • 4 citations