Intraoperative molecular detection of circulating tumor cells by reverse transcription-polymerase chain reaction in patients with biliary-pancreatic cancer is associated with hematogenous metastasis

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Quantitative relationships of intravascular tumor cells, tumor vessels, and pulmonary metastases following tumor implantation.

1974 • 775 citations

Long-Term Survival After Curative Resection for Pancreatic Ductal Adenocarcinoma

1996 • 699 citations

Specific detection of carcinoembryonic antigen-expressing tumor cells in bone marrow aspirates by polymerase chain reaction.

1994 • 382 citations

ELEVATED LEVELS OF CIRCULATING INTERLEUKIN-6 AND TRANSFORMING GROWTH FACTOR-beta 1 IN PATIENTS WITH METASTATIC PROSTATIC CARCINOMA

1999 • 379 citations

Detection of cancer micrometastases in lymph nodes by reverse transcriptase-polymerase chain reaction.

1995 • 366 citations

Detection of breast cancer micrometastases in axillary lymph nodes by using polymerase chain reaction.

1994 • 271 citations

Haematogenous dissemination of prostatic epithelial cells during radical prostatectomy

1995 • 225 citations

Comparative analysis of bone marrow and venous blood isolates from gastrointestinal cancer patients for the detection of disseminated tumor cells using reverse transcription PCR.

1997 • 224 citations

Molecular detection of circulating solid carcinoma cells in the peripheral blood: the concept of early systemic disease

1996 • 201 citations

Prognostic significance of bone marrow micrometastases in patients with gastric cancer.

1996 • 195 citations

Identification of bone marrow micrometastases in patients with prostate cancer

1994 • 159 citations

Marked Elevation of Serum Interleukin-6 in Patients With Cholangiocarcinoma

1998 • 145 citations

Detection of α-fetoprotein mRNA, an indicator of hematogenous spreading hepatocellular carcinoma, in the circulation: A possible predictor of metastatic hepatocellular carcinoma

1994 • 135 citations

Factors in the Production and Growth of tumor Metastases.

1913 • 128 citations

Prognostic value and clinical implications of disseminated cancer cells in the peritoneal cavity detected by reverse transcriptase-polymerase chain reaction and cytology

1998 • 122 citations

Surgical manipulation of VX2 carcinoma in the rabbit liver evokes enhancement of metastasis

1990 • 121 citations

Detection of intraoperative tumor cell dissemination in patients with breast cancer by use of reverse transcription and polymerase chain reaction

1995 • 116 citations

Surgical Maneuvers Enhance Molecular Detection of Circulating Tumor Cells During Gastric Cancer Surgery

2001 • 100 citations

Detection and Prediction of Micrometastasis in the Lymph Nodes of Patients With pN0 Gastric Cancer

2001 • 99 citations

Extended Resections of Ductal Pancreatic Cancer – Impact on Operative Risk and Prognosis

1996 • 68 citations

Molecular detection of circulating cancer cells during surgery in patients with biliary-pancreatic cancer

1999 • 66 citations

Identification of carcinoembryonic antigen mRNA in circulating peripheral blood of pancreatic carcinoma and gastric carcinoma patients

1996 • 63 citations

Detection and Clinical Significance of Lymph Node Micrometastasis Determined by Reverse Transcription-Polymerase Chain Reaction in Patients with Esophageal Carcinoma

2000 • 54 citations

Detection of ras Gene Mutations in Perioperative Peripheral Blood with Pancreatic Adenocarcinoma

1996 • 43 citations

Pancreatic lymph nodal and plexus micrometastases detected by enriched polymerase chain reaction and nonradioisotopic single-strand conformation polymorphism analysis: a new predictive factor for recurrent pancreatic carcinoma.

1997 • 39 citations

Liver metastases after curative resection in patients with distal bile duct cancer

1999 • 33 citations

Comparison of relapse and long-term survival between pylorus-preserving and whipple pancreaticoduodenectomy in periampullary cancer

1998 • 29 citations

EXPERIMENTAL MODEL FOR THE STUDY OF TUMOR CELLS IN THE BLOOD.

1965 • 28 citations

Perioperative change in albumin messenger RNA levels in patients with hepatocellular carcinoma

1998 • 17 citations

Hepatic metastasis of gastroenterological cancer: its tumor biology and oncological surgery.

1999 • 2 citations