Malaria and onchocerciasis: On HLA and related matters

The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens

1987 • 2,403 citations

Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1

1993 • 2,360 citations

Ciba foundation symposium

1964 • 2,217 citations

ANKYLOSING SPONDYLITIS AND HL-A 27

1973 • 1,801 citations

Common West African HLA antigens are associated with protection from severe malaria

1991 • 1,570 citations

High Association of an HL-A Antigen, W27, with Ankylosing Spondylitis

1973 • 1,365 citations

Variation in the TNF-α promoter region associated with susceptibility to cerebral malaria

1994 • 1,199 citations

Histocompatibility Testing 1965

1966 • 1,036 citations

HLA and Disease Associations

1985 • 893 citations

Tumor Necrosis Factor and Disease Severity in Children with Falciparum Malaria

1989 • 852 citations

Tumor Necrosis Factor (Cachectin) as an Essential Mediator in Murine Cerebral Malaria

1987 • 749 citations

Role of MHC Gene Products in Immune Regulation

1981 • 705 citations

Molecular analysis of the association of HLA-B53 and resistance to severe malaria

1992 • 645 citations

Evidence for reactive oxygen intermediates causing hemolysis and parasite death in malaria

1983 • 360 citations

Randomised trial of efficacy of SPf66 vaccine against Plasmodium falciparum malaria in children in southern Tanzania

1994 • 353 citations

Killing of Plasmodium falciparum in vitro by nitric oxide derivatives

1991 • 311 citations

Revisiting and revising suppressor T cells

1992 • 256 citations

Histocompatibility Testing, 1967

1969 • 215 citations

HLA-DQ is epistatic to HLA-DR in controlling the immune response to schistosomal antigen in humans

1987 • 212 citations

Efficacy trial of malaria vaccine SPf66 in Gambian infants

1995 • 192 citations

HLA and disease associations

1986 • 185 citations

The Wellcome Trust Lecture: Infection and disease in lymphatic filariasis: an immunological perspective

1992 • 182 citations

Sporozoite Vaccine Induces Genetically Restricted T Cell Elimination of Malaria from Hepatocytes

1989 • 177 citations

Immune Responsiveness And The Pathogenesis Of Human Onchocerciasis

1995 • 163 citations

Parasite virulence and disease patterns in Plasmodium falciparum malaria.

1994 • 158 citations

Immunology and Molecular Biology of Parasitic Infections

1993 • 151 citations

WORLD MALARIA SITUATION

1974 • 147 citations

Human cytotoxic T lymphocytes against the Plasmodium falciparum circumsporozoite protein.

1991 • 147 citations

Cloned suppressor T cells from a lepromatous leprosy patient suppress Mycobacterium leprae reactive helper T cells

1986 • 140 citations

What is the basis for HLA-DQ associations with autoimmune disease?

1991 • 127 citations

Parasite-specific anergy in human filariasis. Insights after analysis of parasite antigen-driven lymphokine production.

1987 • 126 citations

Impact of malaria on genetic polymorphism and genetic diseases in Africans and African Americans.

1994 • 125 citations

Onchocerciasis and Immunity in Humans: Enhanced T Cell Responsiveness to Parasite Antigen in Putatively Immune Individuals

1988 • 123 citations

Major histocompatibility complex (MHC) control of CD4 T cell subset activation. II. A single peptide induces either humoral or cell‐mediated responses in mice of distinct MHC genotype

1992 • 120 citations

Immunity To Onchocerciasis: Putative Immune Persons Produce A Thl-Like Response To Onchocerca Volvulus

1995 • 120 citations

Prediction of Accelerated Cure in Plasmodium falciparum Malaria by the Elevated Capacity of Tumor Necrosis Factor Production

1995 • 109 citations

Immunology and molecular biology of parasitic infections

1993 • 109 citations

Cell-mediated immune responses in human infection with Onchocerca volvulus.

1988 • 106 citations

Immunological suppression by human CD8+ T cells is receptor dependent and HLA-DQ restricted.

1991 • 103 citations

Non-specific suppression of antigen-induced lymphocyte blastogenesis in Onchocerca volvulus infection in man.

1983 • 87 citations

I-E expression and susceptibility to parasite infection

1987 • 84 citations

Pentoxifylline Prevents Murine Cerebral Malaria

1991 • 84 citations

HLA-D alleles associated with generalized disease, localized disease, and putative immunity in Onchocerca volvulus infection.

1994 • 83 citations

Structure of Plasmodium falciparum liver stage antigen-1

1991 • 75 citations

Immunity to Onchocerciasis: Identification of a Putatively Immune Population in a Hyperendemic Area of Ecuador

1994 • 75 citations

Ivermectin-facilitated immunity in onchocerciasis; activation of parasite-specific Th1-type responses with subclinicalOnchocerca volvulusinfection

1994 • 74 citations

The Role of T Cells in Immunity to Malaria

2015 • 73 citations

Plasmodium falciparum: Immunogenicity of circumsporozoite protein constructs produced in Escherichia coli

1987 • 66 citations

Human autoantibody to defensin: disease association with hyperreactive onchocerciasis (sowda).

1995 • 65 citations

The profile of IgG and IgG subclasses of onchocerciasis patients

1992 • 62 citations

Humoral and Cellular Immune Responses to Onchocerca volvulus Infection in Humans

1985 • 61 citations

WHO expert committee on onchocerciasis

1987 • 53 citations

MHC and malaria: the relationship between HLA class II alleles and immune responses to Plasmodium falciprum

1992 • 50 citations

Cellular and humoral immune responses to Plasmodium falciparum gametocyte antigens in malaria-immune individuals. Limited response to the 48/45-kilodalton surface antigen does not appear to be due to MHC restriction.

1990 • 49 citations

Strong Igg Isotypic Antibody Response In Sowdah Type Onchocerciasis

1994 • 48 citations

Interferon‐γ induced lethality in the late phase of Plasmodium vinckei malaria despite effective parasite clearance by chloroquine

1992 • 47 citations

Guatemalan human onchocerciasis. II. Evidence for IgG3 involvement in acquired immunity to Onchocerca volvulus and identification of possible immune-associated antigens.

1991 • 45 citations

Suppression of human lymphocyte responses to specific and non-specific stimuli in human onchocerciasis

1991 • 44 citations

Analysis of human T cell clones specific for conserved peptide sequences within malaria proteins. Paucity of clones responsive to intact parasites.

1994 • 43 citations

Immunological relationships during primary infection withHeligmosomoides polygyrus(Nematospiroides dubius): H-2 linked genes determine worm survival

1991 • 43 citations

Human antibody responses to Pfs 230, a sexual stage‐specific surface antigen of Plasmodium falciparum: non‐responsiveness is a stable phenotype but does not appear to be genetically regulated

1994 • 42 citations

Immune Response in Patients during and after Plasmodium falciparum Infection

1990 • 40 citations

H-2-controlled, dose-dependent suppression of the response that expels adult Trichinella spiralis from the small intestine of mice.

1984 • 36 citations

Cell-mediated and humoral immune response to tetanus vaccinations in onchocerciasis patients.

1989 • 34 citations

MHC class II (I-A) region control of the IgE antibody repertoire to the ABA-1 allergen of the nematode Ascaris.

1991 • 33 citations

Immune response gene regulation of immunity to Plasmodium berghei sporozoites and circumsporozoite protein vaccines. Overcoming genetic restriction with whole organism and subunit vaccines.

1989 • 33 citations

Description, Mechanisms and Control of Reactions to Treatment in the Human Filariases

2007 • 32 citations

Plasmodium berghei: Cloning of the circumsporozoite protein gene

1987 • 31 citations

HLA-linked immune suppression in humans.

1989 • 29 citations

Human leucocyte antigen (HLA) and malaria morbidity in a Gambian community

1993 • 28 citations

Cytokines in malaria, pathology and protection

1994 • 26 citations

Immediate Hypersensitivity Responses in the Immunopathogenesis of Human Onchocerciasis

1985 • 26 citations

Differences in the distribution of HLA antigens in localized and generalized form of onchocerciasis.

1986 • 20 citations

The Skin and the Immune Response in Onchocerciasis

1992 • 19 citations

Human T-cell responses to blood stage antigens in Plasmodium falciparum malaria

1994 • 17 citations

Met-11 of HLA class II DP alpha 1 first domain associated with onchocerciasis.

1996 • 16 citations

Guatemalan human onchocerciasis. I. Systematic analysis of patient populations, nodular antigens, and specific isotypic reactions.

1991 • 16 citations

Identification and characterization of a parasite antigen in the circulating immune complexes of Onchocerca volvulus infected patients.

1992 • 8 citations

[Factors of humoral and cellular immunity in onchocercosis (results of studies conducted in Senegal)].

1987 • 3 citations