Clinical benefits and mechanisms of a sustained response to intermittent insulin therapy in type 2 diabetic patients with secondary drug failure

Glucose clamp technique: a method for quantifying insulin secretion and resistance.

1979 • 7,240 citations

BMDP Statistical Software 1981.

1984 • 5,347 citations

BMDP Statistical Software 1981

1982 • 2,365 citations

Use of Polyethylene Glycol to Separate Free and Antibody-Bound Peptide Hormones in Radioimmunoassays†

1971 • 1,316 citations

Assessment of Insulin Sensitivityin Vivo*

1985 • 1,076 citations

Effect of fatty acids on glucose production and utilization in man.

1983 • 1,056 citations

A New and Rapid Method for the Determination of Glucose by Measurement of Rate of Oxygen Consumption

1968 • 756 citations

Dose-response characteristics for effects of insulin on production and utilization of glucose in man

1981 • 712 citations

Receptor and postreceptor defects contribute to the insulin resistance in noninsulin-dependent diabetes mellitus.

1981 • 628 citations

Determination of Free and Total Insulin and C-Peptide in Insulin-treated Diabetics

1977 • 593 citations

Diminished B cell secretory capacity in patients with noninsulin-dependent diabetes mellitus.

1984 • 481 citations

The Effect of Insulin Treatment on Insulin Secretion and Insulin Action in Type II Diabetes Mellitus

1985 • 464 citations

Natural Course of Insulin Resistance in Type I Diabetes

1986 • 301 citations

Experimental validation of measurements of glucose turnover in nonsteady state.

1978 • 283 citations

Effect of insulin on the distribution and disposition of glucose in man.

1985 • 259 citations

Insulin Treatment Reverses the Insulin Resistance of Type II Diabetes Mellitus

1982 • 219 citations

Insulin Therapy in Obese, Non-insulin-dependent Diabetes Induces Improvements in Insulin Action and Secretion that Are Maintained for Two Weeks After Insulin Withdrawal

1984 • 189 citations

A rapid micro-scale method for the measurement of haemoglobin A1(a+b+c)

1978 • 146 citations

Improvement of Insulin Secretion but Not Insulin Resistance after Short Term Control of Plasma Glucose in Obese Type II Diabetics*

1982 • 114 citations

Improvement in in vitro insulin action after one month of insulin therapy in obese noninsulin-dependent diabetics. Measurements of glucose transport and metabolism, insulin binding, and lipolysis in isolated adipocytes.

1983 • 96 citations

Insulin binding and action on fat cells from young healthy females and males

1982 • 85 citations

Effect of Insulin Therapy on Insulin Resistance in Type II Diabetic Subjects: Evidence for Heterogeneity

1981 • 77 citations

Basal C-Peptide in the Discrimination of Type I from Type II Diabetes

1981 • 74 citations

Differential effects of insulin therapy on hepatic and peripheral insulin sensitivity in Type 2 (non-insulin-dependent) diabetes

1982 • 57 citations

Insulin Treatment Reverses the Postreceptor Defect in Adipocyte 3-O-Methylglucose Transport in Type II Diabetes Mellitus*

1983 • 56 citations

Assay of glucose transport in human fat cells obtained by needle biopsy

1986 • 22 citations