Phase variation of H. influenzae fimbriae: Transcriptional control of two divergent genes through a variable combined promoter region

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Current protocols in molecular biology

1988 • 7,584 citations

Rapid and simple method for purification of nucleic acids

1990 • 5,273 citations

Slipped-strand mispairing: a major mechanism for DNA sequence evolution.

1987 • 2,272 citations

Generation of single-stranded DNA by the polymerase chain reaction and its application to direct sequencing of the HLA-DQA locus.

1988 • 1,582 citations

pEMBL: a new family of single stranded plasmids

1983 • 1,231 citations

Analysis of E.Coli Pormoter sequences

1987 • 1,029 citations

E. coli RNA polymerase interacts homologously with two different promoters

1980 • 911 citations

Opacity genes in Neisseria gonorrhoeae: Control of phase and antigenic variation

1986 • 428 citations

Defined Nongrowth Media for Stage II Development of Competence in Haemophilus influenzae

1970 • 399 citations

The pathogenicity of Haemophilus influenzae

1984 • 325 citations

The molecular mechanism of phase variation of H. influenzae lipopolysaccharide

1989 • 306 citations

Phase variation of gonococcal pili by frameshift mutation in pilC, a novel gene for pilus assembly.

1991 • 292 citations

MECHANISMS OF SPONTANEOUS AND INDUCED FRAMESHIFT MUTATION IN BACTERIOPHAGE T4

1985 • 292 citations

Mechanisms of mRNA decay in bacteria: a perspective

1988 • 290 citations

Phase Variation of Type 1 Fimbriae in Escherichia coli Is Under Transcriptional Control

1981 • 267 citations

RNA polymerase and the regulation of transcription

1987 • 256 citations

Fimbrial phase variation in Bordetella pertussis: a novel mechanism for transcriptional regulation.

1990 • 207 citations

Genetic Transformation

1981 • 200 citations

Molecular basis of Mycoplasma surface antigenic variation: a novel set of divergent genes undergo spontaneous mutation of periodic coding regions and 5′ regulatory sequences.

1991 • 193 citations

Processed mRNA with differential stability in the regulation of E. coli pilin gene expression

1988 • 174 citations

Spacer mutations in the lac ps promoter.

1982 • 156 citations

VARIATION AND CONTROL OF PROTEIN EXPRESSION IN NEISSERIA

1990 • 151 citations

Interaction of Nontypable Haemophilus influenzae with Human Respiratory Mucosa In Vitro

1991 • 146 citations

Immunoglobulin-like PapD chaperone caps and uncaps interactive surfaces of nascently translocated pilus subunits.

1991 • 131 citations

Control of expression of the Tn10-encoded tetracycline resistance operon II. Interaction of RNA polymerase and TET repressor with the tet operon regulatory region

1984 • 127 citations

Conserved immunoglobulin-like features in a family of periplasmic pilus chaperones in bacteria.

1992 • 123 citations

DO PILI PLAY A ROLE IN PATHOGENICITY OF HAEMOPHILUS INFLUENZAE TYPE B?

1982 • 122 citations

Homogeneity of Cell Envelope Protein Subtypes, Lipopolysaccharide Serotypes, and Biotypes among Haemophilus influenzae Type b from Patients with Meningitis in The Netherlands

1983 • 100 citations

Adherence of Piliated Haemophilus influenzae Type b to Human Oropharyngeal Cells

1982 • 99 citations

Structure and function of peripiasmic chaperone‐like proteins involved in the biosynthesis of K88 and K99 fimbriae in enterotoxigenic Escherichia coli

1991 • 93 citations

RNA polymerase interactions with the upstream region of the E. coli tyrT promoter

1983 • 93 citations

Control of functional mRNA stability in bacteria: multiple mechanisms of nucleolytic and non‐nucleolytic inactivation

1992 • 86 citations

Design and development of pilus vaccines for Haemophilus influenzae diseases

1989 • 83 citations

Blocking of fimbria-mediated adherence of Haemophilus influenzae by sialyl gangliosides

1991 • 81 citations

Pilus- and Non-Pilus-Mediated Interactions of Haemophilus infiuenzae Type b with Human Erythrocytes and Human Nasopharyngeal Mucosa

1990 • 78 citations

The Anton blood group antigen is the erythrocyte receptor forHaemophilus influenzae

1986 • 77 citations

Identification and characterization of precursors in the biosynthesis of the K88ab fimbria of Escherichia coli

1983 • 74 citations

Frequency and properties of naturally occurring adherent piliated strains of Haemophilus influenzae type b

1985 • 73 citations

A lac promoter with a changed distance between -10 and -35 regions

1982 • 60 citations

Interaction of Haemophilus influenzae with human erythrocytes and oropharyngeal epithelial cells is mediated by a common fimbrial epitope

1988 • 59 citations

Inability to express fimbriae results in impaired ability of Haemophilus influenzae b to colonize the nasopharynx

1991 • 57 citations

Cloning and expression in Escherichia coli of Haemophilus influenzae fimbrial genes establishes adherence to oropharyngeal epithelial cells.

1989 • 49 citations

Cloning, expression, and sequence analysis of the Haemophilus influenzae type b strain M43p+ pilin gene

1990 • 40 citations

Multiple determinants of functional mRNA stability: sequence alterations at either end of the lacZ gene affect the rate of mRNA inactivation

1991 • 34 citations

Molecular analysis of the Haemophilus influenzae type b pilin gene

1990 • 30 citations

Regulation of hutUH operon expression by the catabolite gene activator protein-cyclic AMP complex in Klebsiella aerogenes

1984 • 29 citations

Lactose promoter mutation Pr115 activates an overlapping promoter within the lactose control region

1985 • 27 citations

Cloning and expression in Escherichia coli of LKP pilus genes from a nontypeable Haemophilus influenzae strain

1990 • 26 citations

Molecular cloning, expression, and sequence of the pilin gene from nontypeable Haemophilus influenzae M37

1991 • 25 citations

The complete primary structure of pilin fromHaemophilus influenzae type b strain Eagan

1990 • 11 citations