Therapy of primary and metastatic mouse mammary carcinomas with doxorubicin encapsulated in long circulating liposomes

Sterically stabilized liposomes: improvements in pharmacokinetics and antitumor therapeutic efficacy.

1991 • 1,591 citations

Liposomes containing synthetic lipid derivatives of poly(ethylene glycol) show prolonged circulation half-lives in vivo

1991 • 1,370 citations

Liposome formulations with prolonged circulation time in blood and enhanced uptake by tumors.

1988 • 1,103 citations

Preparation of liposomes of defined size distribution by extrusion through polycarbonate membranes

1979 • 1,085 citations

Sterically stabilized liposomes: a hypothesis on the molecular origin of the extended circulation times

1991 • 539 citations

Liposomes with prolonged circulation times: factors affecting uptake by reticuloendothelial and other tissues

1989 • 461 citations

Effect of liposome composition and other factors on the targeting of liposomes to experimental tumors: biodistribution and imaging studies.

1990 • 253 citations

Pharmacokinetics and Tissue Distribution of Doxorubicin Encapsulated in Stable Liposomes With Long Circulation Times

1989 • 210 citations

Characterization, toxicity and therapeutic efficacy of adrïamycin encapsulated in liposomes

1982 • 176 citations

Pharmacokinetic and imaging studies in patients receiving a formulation of liposome-associated adriamycin

1991 • 139 citations

Systemic administration of doxorubicin-containing liposomes in cancer patients: a phase I study

1989 • 123 citations

Hepatic uptake and degradation of unilamellar sphingomyelin/cholesterol liposomes: a kinetic study.

1980 • 94 citations

Superior therapeutic activity of liposome-associated adriamycin in a murine metastatic tumour model

1985 • 93 citations

Inhibition of tumor cell growth in vitro and in vivo by 1-beta-D-arabinofuranosylcytosine entrapped within phospholipid vesicles.

1976 • 81 citations

Increased local antitumor effects of interleukin 2 liposomes in mice with MCA-106 sarcoma pulmonary metastases.

1990 • 63 citations

Collagen production by macrophages in tumour encapsulation and dormancy

1991 • 29 citations

Light microscopic localization of silver-enhanced liposome-entrapped colloidal gold in mouse tissues

1991 • 28 citations

Immunotherapy of a mouse mammary carcinoma by sustained peritumor release of IL‐2

1991 • 21 citations

Clinical Studies with Liposomal Doxorubicin

1990 • 17 citations

Effects of combination drug therapy on the subcutaneous and pulmonary growth of a slow and a fast-growing C3H/He mammary carcinoma.

1979 • 9 citations

[Antitumor effect of IL-2 entrapped in liposomes on rat hepatoma, AH-66].

1989 • 5 citations

Effects on metastases of drug therapy during developing and established tumor immunity

1983 • 2 citations