Transcriptional regulation during T-cell development: the α TCR gene as a molecular model

T-cell antigen receptor genes and T-cell recognition

1988 • 3,099 citations

Multiple nuclear factors interact with the immunoglobulin enhancer sequences

1986 • 2,771 citations

A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins

1989 • 2,706 citations

CREB: a Ca ²⁺ -Regulated Transcription Factor Phosphorylated by Calmodulin-Dependent Kinases

1991 • 1,476 citations

Transcription factor AP-2 mediates induction by two different signal-transduction pathways: Protein kinase C and cAMP

1987 • 1,391 citations

Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1

1991 • 1,321 citations

The molecular control of cell division, differentiation commitment and maturation in haemopoietic cells

1989 • 1,097 citations

Transcription factor ATF cDNA clones: an extensive family of leucine zipper proteins able to selectively form DNA-binding heterodimers.

1989 • 1,046 citations

The macrophage and B cell-specific transcription factor PU.1 is related to the ets oncogene

1990 • 993 citations

Positive and negative regulation of transcription in vitro: Enhancer-binding protein AP-2 is inhibited by SV40 T antigen

1987 • 969 citations

Cloning of cDNA for the major DNA-binding protein of the erythroid lineage through expression in mammalian cells

1989 • 931 citations

A cluster of phosphorylation sites on the cyclic AMP-regulated nuclear factor CREB predicted by its sequence

1989 • 914 citations

Cyclic AMP-Responsive DNA-Binding Protein: Structure Based on a Cloned Placental cDNA

1988 • 772 citations

Activity and tissue-specific expression of the transcription factor NF-E1 multigene family.

1990 • 629 citations

LEF-1, a gene encoding a lymphoid-specific protein with an HMG domain, regulates T-cell receptor alpha enhancer function [corrected]

1991 • 627 citations

The erythroid-specific transcription factor eryf1: A new finger protein

1989 • 608 citations

Identification and cloning of TCF-1, a T lymphocyte-specific transcription factor containing a sequence-specific HMG box.

1991 • 545 citations

A third rearranged and expressed gene in a clone of cytotoxic T lymphocytes

1984 • 528 citations

Developmental regulation of T-cell receptor gene expression

1985 • 522 citations

The c-ets proto-oncogenes encode transcription factors that cooperate with c-Fos and c-Jun for transcriptional activation

1990 • 507 citations

A third type of murine T-cell receptor gene

1984 • 491 citations

A new T-cell receptor gene located within the alpha locus and expressed early in T-cell differentiation

1987 • 483 citations

Expression of an erythroid transcription factor in megakaryocytic and mast cell lineages

1990 • 481 citations

Megakaryocytic and erythrocytic lineages share specific transcription factors

1990 • 446 citations

Leucine zipper structure of the protein CRE-BP1 binding to the cyclic AMP response element in brain.

1989 • 396 citations

A specific member of the ATF transcription factor family can mediate transcription activation by the adenovirus E1a protein

1990 • 391 citations

A thymus-specific member of the HMG protein family regulates the human T cell receptor C alpha enhancer.

1991 • 372 citations

Human GATA-3: a lineage-restricted transcription factor that regulates the expression of the T cell receptor alpha gene.

1991 • 364 citations

Leukemia and the disruption of normal hematopoiesis

1991 • 357 citations

A yeast silencer contains sequences that can promote autonomous plasmid replication and transcriptional activation

1987 • 332 citations

Murine and human T-lymphocyte GATA-3 factors mediate transcription through a cis-regulatory element within the human T-cell receptor delta gene enhancer.

1991 • 316 citations

Ontogeny of the T-cell antigen receptor within the thymus

1985 • 250 citations

Primary structure of human T-cell receptor α-chain

1984 • 245 citations

mXBP/CRE-BP2 and c-Jun form a complex which binds to the cyclic AMP, but not to the 12-O-tetradecanoylphorbol-13-acetate, response element.

1990 • 237 citations

Sequence-Specific Binding of Human Ets-1 to the T Cell Receptor α Gene Enhancer

1990 • 229 citations

Developmental Biology of T Cell Receptors

1989 • 223 citations

Ontogeny of T-cell precursors: a model for the initial stages of human T-cell development

1989 • 222 citations

Molecular interactions within the ecdysone regulatory hierarchy: DNA binding properties of the Drosophila ecdysone-inducible E74A protein

1990 • 195 citations

Sequence-specific DNA binding of the proto-oncoprotein ets-1 defines a transcriptional activator sequence within the long terminal repeat of the Moloney murine sarcoma virus.

1990 • 192 citations

The product of the c-ets-1 proto-oncogene and the related Ets2 protein act as transcriptional activators of the long terminal repeat of human T cell leukemia virus HTLV-1.

1990 • 189 citations

αβ lineage-specific expression of the α T cell receptor gene by nearby silencers

1989 • 182 citations

A novel, inducible and T cell-specific enhancer located at the 3′ end of the T cell receptor alpha locus.

1989 • 176 citations

Cloning of murine TCF-1, a T cell-specific transcription factor interacting with functional motifs in the CD3-epsilon and T cell receptor alpha enhancers.

1991 • 146 citations

A T Cell-Specific Transcriptional Enhancer within the Human T Cell Receptor δ Locus

1990 • 140 citations

Expression of ets genes in mouse thymocyte subsets and T cells.

1989 • 128 citations

Separate lineages of T cells expressing the αβ and γδ receptors

1989 • 118 citations

Identification and functional characterization of the human T-cell receptor beta gene transcriptional enhancer: common nuclear proteins interact with the transcriptional regulatory elements of the T-cell receptor alpha and beta genes.

1990 • 117 citations

Expression of a cAMP receptor gene of Dictyostelium and evidence for a multigene family.

1991 • 103 citations

Distinct Cloned Class II MHC DNA Binding Proteins Recognize the X Box Transcription Element

1988 • 99 citations

Purification of TCF-1 alpha, a T-cell-specific transcription factor that activates the T-cell receptor C alpha gene enhancer in a context-dependent manner.

1990 • 88 citations

A T cell-specific enhancer is located in a DNase I-hypersensitive area at the 3′ end of the CD3-delta gene.

1988 • 81 citations

A 3′ transcriptional enhancer regulates tissue-specific expression of the human CD2 gene.

1990 • 72 citations

The c-ets-1 protein is chromatin associated and binds to DNA in vitro.

1989 • 70 citations

An enhancer located in a CpG-island 3′ to the TCR/CD3-epsilon gene confers T lymphocyte-specificity to its promoter.

1989 • 59 citations

Regulation of the human T-cell receptor alpha gene enhancer: multiple ubiquitous and T-cell-specific nuclear proteins interact with four hypomethylated enhancer elements.

1990 • 52 citations

The T alpha 2 nuclear protein binding site from the human T cell receptor alpha enhancer functions as both a T cell-specific transcriptional activator and repressor.

1990 • 22 citations

Let's hear it for science

1987 • 7 citations