Bioenergetics and Evolutionary Genetics: Opportunities for New Synthesis

The spandrels of San Marco and the Panglossian paradigm: a critique of the adaptationist programme

1979 • 7,466 citations

The Trophic‐Dynamic Aspect of Ecology

1942 • 3,144 citations

The Genetics of Human Populations.

1972 • 1,645 citations

The control of flux.

1973 • 1,381 citations

An Introduction to Population Ecology.

1980 • 1,068 citations

General Conclusions: Teleonomic Mechanisms in Cellular Metabolism, Growth, and Differentiation

1961 • 1,043 citations

Cellular Energy Metabolism and its Regulation

1977 • 961 citations

ISOLATION BY DISTANCE UNDER DIVERSE SYSTEMS OF MATING

1946 • 913 citations

Biochemical systems analysis

1969 • 743 citations

Evolution of a Gene

1975 • 554 citations

The Relationships between Substrates and Enzymes of Glycolysis in Brain

1964 • 551 citations

Behavioral implications of mechanistic ecology

1973 • 457 citations

Physiological and Evolutionary Theories of Dominance

1934 • 340 citations

A GENERAL MODEL TO ACCOUNT FOR ENZYME VARIATION IN NATURAL POPULATIONS

1974 • 306 citations

Enzyme Polymorphism and Metabolism

1974 • 284 citations

The hemoglobins in genetics and evolution

1963 • 254 citations

The contribution of ecological genetics to evolutionary theory: detecting the direct effects of natural selection on particular polymorphic loci.

1975 • 249 citations

PERSPECTIVES IN EVOLUTION

1939 • 240 citations

ADAPTATION AT SPECIFIC LOCI. I. NATURAL SELECTION ON PHOSPHOGLUCOSE ISOMERASE OF COLIAS BUTTERFLIES: BIOCHEMICAL AND POPULATION ASPECTS

1977 • 233 citations

Thermoregulation and Flight in Colias Butterflies: Elevational Patterns and Mechanistic Limitations

1983 • 221 citations

Thermoregulatory Strategies in Colias Butterflies: Thermal Stress and the Limits to Adaptation in Temporally Varying Environments

1983 • 214 citations

The degree of polymorphisms in enzymes involved in energy production compared to that in nonspecific enzymes in two Drosophila ananassae populations.

1968 • 203 citations

ADAPTATION AT SPECIFIC LOCI. III. FIELD BEHAVIOR AND SURVIVORSHIP DIFFERENCES AMONG COLIAS PGI GENOTYPES ARE PREDICTABLE FROM IN VITRO BIOCHEMISTRY

1983 • 201 citations

Testing the Theory of Natural Selection

1972 • 193 citations

SELECTIVE NEUTRALITY OF 6PGD ALLOZYMES IN E. COLI AND THE EFFECTS OF GENETIC BACKGROUND

1980 • 184 citations

The Alcohol Dehydrogenase Polymorphism in Drosophila melanogaster

1982 • 173 citations

Metabolic Control Mechanisms

1964 • 160 citations

Organisms and Molecules in Evolution

1964 • 154 citations

Coupled enzyme assays: A general expression for the transient

1973 • 149 citations

Ecological Significance of Flight Activity in Colias Butterflies: Implications for Reproductive Strategy and Population Structure

1983 • 144 citations

Evolution of five multilocus isozyme systems in the chordates

1980 • 140 citations

Biochemical and physiological correlates of deer mouse alpha-chain hemoglobin polymorphisms.

1984 • 135 citations

On Some Fundamental Concepts of Darwinian Biology

1968 • 132 citations

Asexual Reproduction, Population Structure, and Genotype-Environment Interactions in Sea Anemones

1979 • 120 citations

Physiological effects of an allozyme polymorphism: Glutamate-pyruvate transaminase and response to hyperosmotic stress in the copepod Tigriopus californicus

1983 • 112 citations

Opening Address: The Teleonomic Significance of Biosynthetic Control Mechanisms

1961 • 110 citations

THE ALCOHOL DEHYDROGENASE POLYMORPHISM IN POPULATIONS OF DROSOPHILA MELANOGASTER. I. SELECTION IN DIFFERENT ENVIRONMENTS

1978 • 110 citations

ADAPTATION AT SPECIFIC LOCI. IV. DIFFERENTIAL MATING SUCCESS AMONG GLYCOLYTIC ALLOZYME GENOTYPES OF COLIAS BUTTERFLIES

1985 • 109 citations

Behavioral mechanisms of thermoregulation

1981 • 99 citations

DYNAMICS OF CORRELATED GENETIC SYSTEMS. IV. MULTILOCUS EFFECTS OF ETHANOL STRESS ENVIRONMENTS

1978 • 89 citations

The effect of natural selection on enzymic catalysis

1976 • 89 citations

Effect of an allozyme polymorphism on regulation of cell volume

1982 • 88 citations

Potential for selection among nearly neutral allozymes of 6-phosphogluconate dehydrogenase in Escherichia coli.

1981 • 75 citations

MEASUREMENT OF FITNESS AT THE ESTERASE-5 LOCUS IN DROSOPHILA PSEUDOOBSCURA

1971 • 68 citations

On the genetics of enzyme locational specificity.

1966 • 68 citations

Changes in free amino acid concentrations during osmotic response in the intertidal copepod Tigriopus californicus

1982 • 63 citations

Regulation of the oxidative NADP-enzyme tissue levels inDrosophila melanogaster. I. Modulation by dietary carbohydrate and lipid

1976 • 61 citations

Developmental Genetics of Fishes: Isozymic Analyses of Differential Gene Expression

1981 • 59 citations

Deer Mouse Hemoglobins: Is There Genetic Adaptation to High Altitude?

1981 • 58 citations

EVOLUTION OF THE LACTATE DEHYDROGENASE ISOZYMES OF FISHES

1975 • 58 citations

Population structure of pierid butterflies

1979 • 57 citations

Mechanistic Constraints and Optimality Models: Thermoregulatory Strategies in Colias Butterflies

1984 • 55 citations

Metabolic resource allocation vs. mating attractiveness: Adaptive pressures on the “alba” polymorphism of Colias butterflies

1980 • 55 citations

Isozymes as probes and participants in developmental and evolutionary genetics.

1983 • 47 citations

Polymorphism at the G6PD and 6PGD loci inDrosophila melanogaster: I. Evidence for selection in experimental populations

1977 • 46 citations

VIABILITY INTERACTIONS, IN VIVO ACTIVITY AND THE G6PD POLYMORPHISM IN DROSOPHILA MELANOGASTER

1984 • 36 citations

Polymorphism at the G6PD and 6PGD loci inDrosophila melanogaster

1978 • 35 citations

THE RESPONSE OF ENZYME POLYMORPHISMS TO DEVELOPMENTAL RATE SELECTION IN DROSOPHILA MELANOGASTER

1983 • 33 citations

DYNAMICS OF CORRELATED GENETIC SYSTEMS. V. RATES OF DECAY OF LINKAGE DISEQUILIBRIA IN EXPERIMENTAL POPULATIONS OF DROSOPHILA MELANOGASTER

1980 • 32 citations

Organization of glycolysis: oscillatory and stationary control.

1973 • 28 citations

The effect of environmental uncertainty on morphological design and fluid balance in Sarracenia purpurea L.

1981 • 17 citations

Polymorphism at the G6pd and 6Pgd loci in Drosophila melanogaster. IV. Genetic factors modifying enzyme activity

1980 • 17 citations

Rates of decay of linkage disequilibrium under two-locus models of selection

1982 • 14 citations

Metabolism and bioenergetics.

1948 • 12 citations

Natural Selection as a Law: Principles and Processes

1983 • 11 citations

REGULATION OF ENZYME ACTIVITIES IN DROSOPHILA: GENETIC VARIATION AFFECTING INDUCTION OF GLUCOSE 6-PHOSPHATE AND 6-PHOSPHOGLUCONATE DEHYDROGENASES IN LARVAE

1983 • 11 citations

Evolutionary Adaptation of Mitochondrial Cytochrome c to Its Functional Milieu

1980 • 7 citations

Regulation of Micronutrilite Synthesis

1981 • 3 citations