2′,3′-Cyclic Nucleotide 3′-Phosphodiesterase

Mutant Mice (Quaking and Jimpy) with Deficient Myelination in the Central Nervous System

1964 • 607 citations

THE REGIONAL AND SUBCELLULAR DISTRIBUTION OF 2′,3′‐CYCLIC NUCLEOTIDE 3′‐PHOSPHOHYDROLASE IN THE CENTRAL NERVOUS SYSTEM

1967 • 458 citations

Methods of Neurochemistry

1973 • 454 citations

The Structure and Function of Nervous Tissue

1969 • 429 citations

Isolation and Characterization of Myelin

1977 • 389 citations

ISOLATION AND SOME CHEMICAL PROPERTIES OF OLIGODENDROGLIA FROM CALF BRAIN¹

1972 • 278 citations

Improved rapidity and precision in the determination of brain 2′,3′-cyclic nucleotide 3′-phosphohydrolase

1973 • 244 citations

Studies on 2′,3′-cyclic nucleotide-3′-phosphohydrolase from brain

1969 • 216 citations

EVIDENCE FOR THE CLOSE ASSOCIATION OF A GLYCOPROTEIN WITH MYELIN IN RAT BRAIN

1973 • 208 citations

Enzyme activity and composition of myelin and subcellular fractions in the developing rat brain

1969 • 207 citations

Chemical Pathology of G_M1-Gangliosidosis (Generalized Gangliosidosis)

1969 • 207 citations

Enzymatic Hydrolysis of Adenosine 3',5'-Phosphoric Acid

1961 • 206 citations

Hydrolysis of Ribonucleoside 2‘,3‘-Cyclic Phosphates by a Diesterase from Brain

1962 • 198 citations

2′,3′‐CYCLIC NUCLEOTIDE 3′‐PHOSPHOHYDROLASE IN BRAINS OF MUTANT MICE WITH DEFICIENT MYELINATION

1970 • 185 citations

COPPER DEFICIENCY IN THE DEVELOPING RAT BRAIN: A POSSIBLE MODEL FOR MENKES’ STEELY‐HAIR DISEASE

1974 • 183 citations

Biochemically Differentiated Neoplastic Clone of Schwann Cells

1972 • 165 citations

[77] Destabilization of membranes with chaotropic ions

1974 • 160 citations

Subacute Sclerosing Leukoencephalitis^*†‡

1966 • 159 citations

THE ISOLATION AND CHARACTERIZATION OF A PLASMA MEMBRANE AND A MYELIN FRACTION DERIVED FROM OLIGODENDROGLIA OF CALF BRAIN

1975 • 158 citations

The identity of a myelin-like fraction isolated from developing brain

1970 • 155 citations

2',3'-CYCLIC NUCLEOTIDE 3'-PHOSPHOHYDROLASE IN THE DEVELOPING CHICK BRAIN AND SPINAL CORD

1968 • 153 citations

The presence of 2′, 3′‐cyclic AMP 3′‐phosphohydrolase in glial cells in tissue culture

1972 • 148 citations

In Vitro and in Vivo Phosphorylation of Myelin Basic Protein by Exogenous and Endogenous Adenosine 3′ : 5′-Monophosphate-dependent Protein Kinases in Brain

1974 • 145 citations

2′,3′‐CYCLIC NADP AS A SUBSTRATE FOR 2′,3′‐CYCLIC NUCLEOTIDE 3′‐PHOSPHOHYDROLASE

1976 • 139 citations

ENZYME INACTIVITY OF MYELIN: HISTOCHEMICAL AND BIOCHEMICAL EVIDENCE

1963 • 128 citations

Variation of proteins, enzyme markers and gangliosides in myelin subfractions

1973 • 126 citations

Undernutrition in the developing rat: effect upon myelination

1976 • 124 citations

Phosphorylation of selected serine and threonine residues in myelin basic protein by endogenous and exogenous protein kinases

1974 • 115 citations

Myelin synthesis during postnatal nutritional deprivation and subsequent rehabilitation

1976 • 114 citations

COMPARATIVE STUDIES ON THE MYELIN PROTEINS OF BOVINE PERIPHERAL NERVE AND SPINAL CORD

1972 • 112 citations

THE ISOLATION AND CHARACTERIZATION OF A PLASMA MEMBRANE AND A MYELIN FRACTION DERIVED FROM OLIGODENDROGLIA OF CALF BRAIN

1975 • 110 citations

Isolation of rat brain myelin, monitored by polyacrylamide gel electrophoresis of dodecyl sulfate-extracted proteins

1972 • 104 citations

Experimental allergic encephalomyelitis. Antiserum inhibition of myelination in vitro.

1970 • 101 citations

Phosphorylation of Myelin Basic Protein

1974 • 97 citations

Metabolic studies on myelin. Evidence for a precursor role of a myelin subfraction

1974 • 93 citations

EXPERIMENTALLY INDUCED CHANGES IN THE BASE COMPOSITION OF THE RIBONUCLEIC ACIDS OF ISOLATED NERVE CELLS AND THEIR OLIGODENDROGLIAL CELLS

1961 • 93 citations

Ontogenetic study of a myelin-derived fraction with 2′:3′-cyclic nucleotide 3′-phosphodydrolase activity higher than that of myelin

1975 • 91 citations

2′, 3′-Cyclic nucleotide 3′-phosphohydrolase in the brain of the “Jimpy” mouse, a mutant with deficient myelination

1969 • 89 citations

Cholesterol Ester Metabolism in Rat Brain

1973 • 87 citations

Hypomyelination in Copper-Deficient Rats

1976 • 83 citations

Relation of C-6 glial cells in culture to myelin

1975 • 82 citations

Biochemically differentiated mouse glial lines carrying a nervous system specific cell surface antigen (NS-1).

1975 • 82 citations

Ribonucleoside 2′,3′-cyclic phosphate diesterase activity and cerebroside levels in vertebrate and invertebrate nerve

1971 • 78 citations

CHARACTERIZATION AND PROTEIN ANALYSIS OF MYELIN SUBFRACTIONS IN RAT BRAIN: DEVELOPMENTAL AND REGIONAL COMPARISONS

1975 • 78 citations

2′, 3′-cyclic nucleotide 3′-phosphohydrolase in purified myelin from brain of Jimpy and normal young mice

1971 • 75 citations

Influence of Thyroid Hormones on Enzyme Activities of Myelinating Rat Central‐Nervous Tissues

1972 • 74 citations

Immunochemical measurement of myelin basic protein in developing rat brain: An index of myelin synthesis

1976 • 73 citations

Norepinephrine induces glial-specific enzyme activity in cultured plasma glioma cells.

1977 • 73 citations

The enzymic hydrolysis of ribonucleoside-2′:3′ phosphates

1955 • 71 citations

THE BIOSYNTHESIS AND CONCENTRATION OF GALACTOSYL DIGLYCERIDE IN GLIAL AND NEURONAL ENRICHED FRACTIONS OF ACTIVELY MYELINATING RAT BRAIN

1974 • 66 citations

2′, 3′-cyclic nucleotide 3′-phosphodiesterase in the nervous system. Electrophoretic properties and developmental studies

1972 • 63 citations

ULTRASTRUCTURAL AND BIOCHEMICAL STUDIES OF SCHILDERʼS DISEASE

1970 • 60 citations

CHARACTERIZATION OF THE FRACTION OBTAINED FROM THE CNS OF JIMPY MICE BY A PROCEDURE FOR MYELIN ISOLATION

1974 • 60 citations

2′,3′-cyclic nucleotide 3′-phosphohydrolase in human erythrocyte membranes

1972 • 58 citations

BIOCHEMICAL STUDIES OF MYELIN IN WALLERIAN DEGENERATION OF RAT OPTIC NERVE

1973 • 58 citations

Lipids, Malnutrition and the Developing Brain: A Ciba Foundation Symposium.

1973 • 54 citations

Proteins of rat brain myelin in neonatal hypothyroidism

1975 • 53 citations

Biochemical and pathological studies of myelin in hexachlorophene intoxication

1975 • 53 citations

MYELIN PROTEINS FROM DIFFERENT REGIONS OF THE CENTRAL NERVOUS SYSTEM

1974 • 51 citations

[12] Mammalian membrane marker enzymes: Sensitive assay for 5′-nucleotidase and assay for mammalian 2′,3′-cyclic-nucleotide-3′-phosphohydrolase

1974 • 49 citations

Spectrophotometric assay of 2′,3′-cyclic nucleotide 3′-phosphohydrolase: Application to the enzyme in bovine brain

1973 • 49 citations

Effects of a postnatal protein deficiency on the content and composition of myelin from brains of weanling rats

1975 • 47 citations

Immunopathological comparisons between experimental autoimmune encephalomyelitis and multiple sclerosis.

1973 • 44 citations

A specific phosphodiesterase from beef pancreas

1956 • 43 citations

PHOSPHORYLATION OF ENDOGENOUS PROTEINS IN MYELIN OF RAT BRAIN

1976 • 41 citations

Hexachlorophene intoxication: Characterization of myelin and myelin related fractions in the rat during early postnatal development

1974 • 41 citations

THE COMPOSITION OF MYELIN FROM THE MUTANT MOUSE ‘QUAKING’

1972 • 40 citations

Studies on the pathogenesis of multiple sclerosis

1972 • 40 citations

A RAPID ASSAY FOR 2′,3′‐CYCLIC NUCLEOTIDE 3′‐PHOSPHORYDROLASE¹

1976 • 39 citations

Influence of thyroid hormones on myelin proteins in the developing rat brain

1975 • 39 citations

Experimental inhibition of myelination in spinal cord tissue cultures: Enzyme assays

1973 • 39 citations

Changes in cathepsins B-1 and D, neutral proteinase and 2′,3′-cyclic nucleotide-3′-phosphohydrolase activities in monkey brain with experimental allergic encephalomyelitis

1974 • 38 citations

Phosphoprotein phosphatases for myelin basic protein in myelin and cytosol fractions of brain

1975 • 38 citations

Effects of Triethyltin on Different ATPases, 5′-Nucleotidase and Phosphodiesterases in Grey and White Matter of Rabbit Brain and their Relation with Brain Edema

1973 • 38 citations

Isolation of axolemma-enriched fractions from bovine central nervous system

1976 • 36 citations

POTENTIOMETRIC AND COLORIMETRIC METHODS FOR THE ASSAY OF 2′,3′‐CYCLIC NUCLEOTIDE 3′‐PHOSPHOHYDROLASE¹

1973 • 36 citations

Criteria for identifying a myelin-like fraction from developing brain (Short Communication)

1973 • 36 citations

BIOCHEMICAL STUDIES ON MYELIN ISOLATED FROM THE BRAINS OF PATIENTS WITH DOWN'S SYNDROME

1975 • 33 citations

Effect of Zinc Deficiency from Day 18 of Gestation and/or during Lactation on the Development of Some Rat Brain Enzymes

1974 • 33 citations

PRENATAL AND POSTNATAL PROTEIN RESTRICTION IN THE RAT: EFFECT ON SOME PARAMETERS RELATED TO BRAIN DEVELOPMENT, AND PROSPECTS FOR REHABILITATION^1,2

1976 • 32 citations

Redistribution of rat brain esterases during subcellular fractionation

1969 • 32 citations

THE NON‐SYNCHRONOUS SYNTHESIS OF MYELIN COMPONENTS DURING EARLY STAGES OF MYELINATION IN THE RAT OPTIC NERVE¹

1976 • 30 citations

Ribonucleases of beef brain nuclei. Purification and characterization of an alkaline RNAase

1974 • 29 citations

p-Chlorophenylalanine treatment in developing rats: protein and lipids in whole brain and myelin

1974 • 27 citations

Solubilization of 2′,3′-cyclic nucleotide 3′-phosphohydrolase from bovine brain without detergents

1975 • 27 citations

Clonal Lines of Glial Cells

1973 • 25 citations

Biochemical and Morphological Changes in the Subcellular Fractions during Myelination of Rat Brain

1975 • 22 citations

2′,3′‐Cyclic AMP 3’‐phosphohydrolase activity during Wallerian degeneration

1974 • 21 citations

Enzyme nomenclature: Recommendations (1972) of the International Union of Pure and Applied Chemistry and the International Union of Biochemistry

1976 • 19 citations

Cyclic nucleotide phosphodiesterase in silkworm: Purification and properties

1974 • 19 citations

2′,3′‐Cyclic nucleotide 3′‐phosphohydrolase activity in human brain tumours

1974 • 19 citations

Myelin Deficiency in Hereditary Pituitary Dwarfism: A Biochemical and Morphological Study

1975 • 19 citations

The use of non-aqueous chloroform/methanol extraction for the delipidation of brain with minimal loss of enzyme activities

1977 • 17 citations

ON THE ASSOCIATION OF NON‐SPECIFIC ESTERASE ACTIVITY WITH CENTRAL NERVE MYELIN PREPARATIONS

1973 • 17 citations

Effect of detergents on 2',3'-cyclic nucleotide 3'-phosphohydrolase activity in myelin and erythrocyte ghosts.

1974 • 17 citations

Development of biochemical activities associated with myelination in chick brain aggregate cultures

1975 • 16 citations

Biochemical and ultrastructural studies on subacute sclerosing panencephalitis and demyelination

1974 • 16 citations

Triethyllead-restrained myelin deposition and protein synthesis in the developing rat forebrain

1976 • 15 citations

Hydrolytic enzyme activities in the developing chick central and peripheral nervous systems

1974 • 14 citations

Demonstration of enzymes related to myelinogenesis in established human brain cell cultures

1975 • 14 citations

Hydrolysis of 2′,3′-cyclic adenosine monophosphate and 3′,5′-cyclic adenosine monophosphate in subcellular fractions of normal and neoplastic mouse spleen

1974 • 14 citations

Arrested development of myelin in chick optic tectum following deafferentation

1972 • 12 citations

A rapid fluorometric assay for 2′,3′‐cyclic adenosine monophosphate 3′‐phosphoesterhydrolase

1973 • 12 citations

Effect of 1,1,3-tricyano-2-amino-1-propene on 2′,3′-cyclic AMP 3′-phosphohydrolase in the sciatic nerve of the chick embryo

1972 • 12 citations

Esterases in developing CNS myelin

1971 • 11 citations

Studies on the solubilization of 2′,3′-cyclic nucleotide 3′-phosphohydrolase from bovine brain

1969 • 11 citations

Fluorometric assay of 2′, 3′ ‐cyclic adenosine monophosphate 3′‐phosphohydrolase with 1,N⁶‐etheno‐2‐aza‐adenosine 2′, 3′ ‐monophosphate¹

1975 • 11 citations

PEPTIDASE ACTIVITY OF PURIFIED MYELIN

1970 • 10 citations

2′, 3′-Cyclic Nucleotide 3′-Phosphohydrolase Activity in Myelin Fractions from One Patient with Schilder's Disease

1971 • 9 citations

The activity of 2′,3′-cyclic adenosine monophosphate 3′-phosphoesterhydrolase in elasmobranch and teleost brain

1974 • 8 citations

Effect of Phenylalanine and p-Chlorophenylalanine Administration on the Development of Rat Brain 2',3'-Cyclic Nucleotide 3'-Phosphohydrolase

1974 • 6 citations

Aminopeptidase and neutral proteinase activity associated with central nerve myelin preparations during purification

1972 • 5 citations

Enzyme activity of human central nervous system myelin

1974 • 5 citations

2′,3′‐Cyclic nucleotide 3′‐phosphohydrolase activity of the central nervous tissue in experimental allergic encephalomyelitis

1972 • 5 citations

Proteins and enzymes of myelin

1977 • 4 citations