Post-transcriptional Regulation of Human Interleukin-2 Gene Expression at Processing of Precursor Transcripts

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

1986 • 4,200 citations

Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators.

1986 • 1,591 citations

Structure and expression of a cloned cDNA for human interleukin-2

1983 • 1,176 citations

Regulation of Lymphokine Messenger RNA Stability by a Surface-Mediated T Cell Activation Pathway

1989 • 910 citations

Messenger RNA degradation in eukaryotes

1993 • 858 citations

Removal of poly(A) and consequent degradation of c-fos mRNA facilitated by 3′ AU-rich sequences

1988 • 691 citations

The IL-2 Receptor Complex: Its Structure, Function, and Target Genes

1993 • 601 citations

Interleukin 2

1984 • 497 citations

The protein-coding region of c-myc mRNA contains a sequence that specifies rapid mRNA turnover and induction by protein synthesis inhibitors.

1991 • 297 citations

Differential expression of alternative 5' untranslated regions in mRNAs encoding rat insulin-like growth factor I.

1987 • 292 citations

Sequential expression of genes involved in human T lymphocyte growth and differentiation.

1985 • 291 citations

Regulation of c-myc mRNA Stability In Vitro by a Labile Destabilizer with an Essential Nucleic Acid Component

1989 • 172 citations

Control of biologically active interleukin 2 messenger RNA formation in induced human lymphocytes.

1984 • 141 citations

Selective Destabilization of Short-Lived mRNAs with the Granulocyte-Macrophage Colony-Stimulating Factor AU-Rich 3' Noncoding Region Is Mediated by a Cotranslational Mechanism

1993 • 131 citations

Posttranscriptional gene regulation and specific binding of the nonhistone protein HMG-I by the 3' untranslated region of bovine interleukin 2 cDNA.

1987 • 128 citations

Translation and the stability of mRNAs encoding the transferrin receptor and c-fos.

1991 • 127 citations

T-cell growth factor: complete nucleotide sequence and organization of the gene in normal and malignant cells.

1984 • 113 citations

Kinetics of induction and molecular size of mRNAs encoding human interleukin-2 and γ-interferon

1982 • 104 citations

Nuclear posttranscriptional processing of thymidine kinase mRNA at the onset of DNA synthesis.

1988 • 94 citations

Induction, suppression and superinduction of lymphokine mRNA in T lymphocytes

1987 • 82 citations

Post-Transcriptional Control of Class I MHC mRNA Expression in Adenovirus 12-Transformed Cells

1987 • 79 citations

Induction of human interleukin-1 gene expression by retinoic acid and its regulation at processing of precursor transcripts.

1994 • 75 citations

Studies on induction and effector functions of concanavalin A-induced suppressor cells that limit TCGF production.

1982 • 53 citations

RNA processing is a limiting step for murine tumor necrosis factor beta expression in response to interleukin-2.

1990 • 52 citations

Superinduction of human interleukin-2 messenger RNA by inhibitors of translation

1984 • 47 citations

Superinduction of the human gene encoding immune interferon.

1987 • 41 citations

Survival and PHA-stimulation of γ-irradiated human peripheral blood T lymphocyte subpopulations

1983 • 30 citations

Transient expression of human interleukin-2 and interferon-γ genes is regulated by interaction between distinct cell subsets

1995 • 11 citations

Regulation of Human Interleukin‐2 and Interferon‐Gamma Gene Expression by Suppressor T Lymphocytes

1991 • 9 citations