The role of multiple opioid receptors in the maintenance of stimulation-induced feeding

Anatomy of CNS opioid receptors

1988 • 1,178 citations

Naltrindole, a highly selective and potent non-peptide δ opioid receptor antagonist

1988 • 599 citations

Binaltorphimine and nor-binaltorphimine, potent and selective k-opioid receptor antagonists

1987 • 529 citations

Dynorphin1–8 and dynorphin1–9 are ligands for the κ-subtype of opiate receptor

1982 • 448 citations

Behavioral effects of separate and combined administration of naloxone and d-amphetamine.

1974 • 411 citations

Nor-binaltorphimine, a highly selective kappa-opioid antagonist in analgesic and receptor binding assays.

1988 • 399 citations

Application of the message-address concept in the design of highly potent and selective non-peptide .delta. opioid receptor antagonists

1988 • 298 citations

The irreversible narcotic antagonistic and reversible agonistic properties of the fumaramate methyl ester derivative of naltrexone

1981 • 229 citations

Extremely long-lasting antagonistic actions of nor-binaltorphimine (nor-BNI) in the mouse tail-flick test.

1992 • 206 citations

Site-directed alkylation of multiple opioid receptors. I. Binding selectivity.

1984 • 200 citations

Evidence that the aversive effects of opioid antagonists and ?-agonists are centrally mediated

1989 • 193 citations

Naltrexone suppresses hyperphagia induced in the rat by a highly palatable diet

1981 • 187 citations

Selectivity of Ligands for Opioid Receptors

1993 • 186 citations

Flavor enhances the antidipsogenic effect of naloxone

1982 • 150 citations

Pain modulating and reward systems: A single brain mechanism?

1980 • 148 citations

The stimulation of food intake by selective agonists of mu, kappa and delta opioid receptors

1986 • 146 citations

Design and synthesis of somatostatin analogs with topographical properties that lead to highly potent and specific .mu. opioid receptor antagonists with greatly reduced binding at somatostatin receptors

1988 • 130 citations

Morphine- and naltrexone-induced modification of palatability: Analysis by the taste reactivity test.

1992 • 126 citations

Morphine- and naltrexone-induced modification of palatability: Analysis by the taste reactivity test.

1992 • 118 citations

Opiate blockade inhibits saccharin intake and blocks normal preference acquisition

1986 • 117 citations

Naloxone modifies sugar-water intake in rats drinking with open gastric fistulas

1982 • 111 citations

Centrally administered opioid peptides stimulate saccharin intake in nondeprived rats

1989 • 100 citations

Attenuation of sham feeding by naloxone is stereospecific: Evidence for opioid mediation of orosensory reward

1988 • 93 citations

A new approach to receptor ligand design: synthesis and conformation of a new class of potent and highly selective μ opioid antagonists utilizing tetrahydroisoouinoline carroxylic acid

1988 • 92 citations

Nor-binaltorphimine decreases deprivation and opioid-induced feeding

1990 • 91 citations

Central opioid receptor subtype antagonists differentially alter sucrose and deprivation-induced water intake in rats

1992 • 87 citations

Suppression of nocturnal, palatable and glucoprivic intake in rats by the κ opioid antagonist, nor-binaltorphamine

1990 • 87 citations

Long term κ-opioid receptor blockade following nor-binaltorphimine

1992 • 87 citations

Effect of naloxone and naltrexone on the development of satiation measured in the runway: Comparisons with d-amphetamine and d-fenfluramine

1986 • 79 citations

Reduction by central ß-funaltrexamine of food intake in rats under freely-feeding, deprivation and glucoprivic conditions

1990 • 79 citations

Evidence for two subtypes of δ opioid receptors in rat brain

1991 • 79 citations

Selective opioid receptor antagonist effects upon intake of a high-fat diet in rats

1990 • 65 citations

Potentiation of reward by hunger is opioid mediated

1984 • 63 citations

Effects of naloxone and its quarternary analogue on stimulation-induced feeding

1983 • 58 citations

Effects of β-funaltrexamine on ingestive behaviors in the rat

1988 • 56 citations

Ingestive behavior following central [D-Ala2, Leu5, Cys6]-Enkephalin (DALCE), a short-acting agonist and long-acting antagonist at the delta opioid receptor

1991 • 53 citations

The role of multiple opioid receptors in the potentiation of reward by food restriction

1994 • 49 citations

Are δ-opioid receptors involved in the regulation of food and water intake?

1985 • 48 citations

Autoradiographic localization of kappa opiate receptors in CNS taste and feeding areas

1985 • 47 citations

ß-Funaltrexamine (ß-FNA) decreases deprivation and opioid-induced feeding

1991 • 45 citations

An observational analysis of the effect of the selective kappa opioid agonist, U-50,488H, on feeding and related behaviours in the rat

1986 • 44 citations

Centrally administered opioid antagonists, nor-binaltorphimine, 16-methyl cyprenorphine and MR2266, suppress intake of a sweet solution

1990 • 38 citations

Microinjection of opioid antagonists into the substantia nigra reduces stress-induced eating in rats

1992 • 36 citations

TONIC PROPERTIES OF ***OROSENSATION AND THE MODULATION OF INTRACRANIAL SELF‐STIMULATION: THE CNS WEIGHTING OF EXTERNAL AND INTERNAL FACTORS GOVERNING REWARD

1977 • 36 citations

Opioid effects on intake of sweet solutions depend both on prior drug experience and on prior ingestive experience

1990 • 35 citations

Antibodies to dynorphin A(1–13) but not β-endorphin inhibit electrically elicited feeding in the rat

1987 • 33 citations

Mediation of insulin hyperphagia by specific central opiate receptor antagonists

1991 • 32 citations

Effects of the selective kappa opioid antagonist, nor-binaltorphimine, on electrically-elicited feeding in the rat

1989 • 31 citations

Effects of antibodies to dynorphin A and β-endorphin on lateral hypothalamic self-stimulation in ad libitum fed and food-deprived rats

1990 • 28 citations

Rostral and caudal ventricular infusion of antibodies to dynorphin A(1–17) and dynorphin A(1–8): effects on electrically-elicited feeding in the rat

1990 • 21 citations

Enhancement of the prophagic but not of the antidipsogenic effect of U-50, 488H after chronic amphetamine

1993 • 20 citations

Norbinaltorphimine blocks the feeding but not the reinforcing effect of lateral hypothalamic electrical stimulation

1993 • 19 citations

Antagonist activity of the cyclic somatostatin analogue CTP at μ- but not δ- and κ;;-opioid receptors involved in presynaptic inhibition of neurotransmitter release

1988 • 5 citations