Ionomycin, Thapsigargin, Ryanodine, and Sperm Induced Ca2+ Release Increase during Meiotic Maturation of Mouse Oocytes

Inositol trisphosphate and calcium signalling

1993 • 6,546 citations

Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase.

1990 • 3,250 citations

The Physiology of Reproduction

1988 • 3,218 citations

Maturation in vitro of Mouse, Sheep, Cow, Pig, Rhesus Monkey and Human Ovarian Oocytes

1965 • 835 citations

Ryanodine activation and inhibition of the Ca2+ release channel of sarcoplasmic reticulum.

1986 • 710 citations

Repetitive calcium transients and the role of calcium in exocytosis and cell cycle activation in the mouse egg

1992 • 693 citations

Preservation of hamster oocytes to assay the fertilizing capacity of human spermatozoa

1982 • 653 citations

Activation of mammalian oocytes by intracellular injection of calcium

1978 • 582 citations

Ryanodine modifies conductance and gating behavior of single Ca2+ release channel

1987 • 548 citations

Essential Role of the Inositol 1,4,5-Trisphosphate Receptor/Ca2+ Release Channel in Ca2+ Waves and Ca2+ Oscillations at Fertilization of Mammalian Eggs

1993 • 521 citations

Block of Ca ²⁺ Wave and Ca ²⁺ Oscillation by Antibody to the Inositol 1,4,5-Trisphosphate Receptor in Fertilized Hamster Eggs

1992 • 493 citations

Phorbol ester and sperm activate mouse oocytes by inducing sustained oscillations in cell Ca2+

1985 • 434 citations

Free Ca2+ increases in exponential phases during mouse oocyte activation

1981 • 322 citations

Relationship between the Developmental Programs Controlling Nuclear and Cytoplasmic Maturation of Mouse Oocytes

1994 • 317 citations

Calcium-dependent immediate feedback control of inositol 1,4,5-trisphosphate-induced Ca2+ release

1992 • 291 citations

Agonist-induced oscillations in cytoplasmic free calcium concentration in single rat hepatocytes

1987 • 271 citations

Inositol 1,4,5-trisphosphate-induced calcium release and guanine nucleotide-binding protein-mediated periodic calcium rises in golden hamster eggs

1988 • 256 citations

Expression of a Ryanodine Receptor-Ca ²⁺ Channel that is Regulated by TGF-β

1992 • 247 citations

Meiosis, egg activation, and nuclear envelope breakdown are differentially reliant on Ca2+, whereas germinal vesicle breakdown is Ca2+ independent in the mouse oocyte

1992 • 241 citations

Effects of altered extracellular and intracellular calcium concentration on hyperpolarizing responses of the hamster egg.

1983 • 235 citations

Mouse oocytes gradually develop the capacity for activation during the metaphase II arrest

1989 • 214 citations

Structural and Functional Characterization of the Purified Cardiac Ryanodine Receptor-Ca2+ Release Channel Complex

1989 • 209 citations

Behavior of hamster sperm nuclei incorporated into eggs at various stages of maturation, fertilization, and early development. The appearance and disappearance of factors involved in sperm chromatin decondensation in egg cytoplasm

1976 • 207 citations

Spontaneous cytosolic calcium oscillations driven by inositol trisphosphate occur during in vitro maturation of mouse oocytes.

1992 • 169 citations

Development of Inositol Trisphosphate-Induced Calcium Release Mechanism during Maturation of Hamster Oocytes

1993 • 167 citations

Different triggers for calcium oscillations in mouse eggs involve a ryanodine-sensitive calcium store

1992 • 166 citations

Calcium-dependent events at fertilization of the frog egg: Injection of a calcium buffer blocks ion channel opening, exocytosis, and formation of pronuclei

1988 • 163 citations

Incidence of chromosome anomalies in first‐cleavage mouse embryos obtained from frozen‐thawed oocytes fertilized in vitro

1987 • 159 citations

Spatiotemporal dynamics of intracellular [Ca2+]i oscillations during the growth and meiotic maturation of mouse oocytes

1994 • 152 citations

Thapsigargin activates a calcium influx pathway in the unfertilized mouse egg and suppresses repetitive calcium transients in the fertilized egg.

1992 • 141 citations

Luminal Ca2+ promoting spontaneous Ca2+ release from inositol trisphosphate‐sensitive stores in rat hepatocytes.

1992 • 138 citations

Functional expression of the calcium release channel from skeletal muscle ryanodine receptor cDNA

1989 • 122 citations

Regulation of Intracellular Calcium in the Mouse Egg: Evidence for Inositol Trisphosphate-Induced Calcium Release, but not Calcium-Induced Calcium Release1

1994 • 121 citations

Fertilization and early embryology: Oscillations in intracellular free calcium induced by spermatozoa in human oocytes at fertilization

1993 • 118 citations

Cortical localization of a calcium release channel in sea urchin eggs.

1992 • 118 citations

Changes in the Distribution of Mouse Oocyte Cortical Granules and Ability to Undergo the Cortical Reaction during Gonadotropin-stimulated Meiotic Maturation and Aging in Vivo1

1990 • 115 citations

Ca2+ oscillations and sensitization of Ca2+ release in unfertilized mouse eggs injected with a sperm factor

1994 • 115 citations

Regulation of the Polyspermy Block in the Mouse Egg: Maturation-Dependent Differences in Cortical Granule Exocytosis and Zona Pellucida Modifications Induced by Inositol 1,4,5-Trisphosphate and an Activator of Protein Kinase C1

1993 • 107 citations

Periodic increase of cytoplasmic free calcium in fertilized hamster eggs measured with calcium‐sensitive electrodes.

1986 • 101 citations

Enhancement of Ca²⁺ release channel activity by phosphorylation of the skeletal muscle ryanodine receptor

1993 • 98 citations

Antibody to the inositol trisphosphate receptor blocks thimerosalenhanced Ca²⁺‐induced Ca²⁺ release and Ca²⁺ oscillations in hamster eggs

1992 • 91 citations

Free cytoplasmic Ca2+ concentration oscillations in thapsigargin-treated parotid acinar cells are caffeine- and ryanodine-sensitive

1991 • 89 citations

Quantal Ca2+ release from caffeine-sensitive stores in adrenal chromaffin cells.

1993 • 86 citations

Bovine adrenal chromaffin cells contain an inositol 1,4,5-trisphosphate-insensitive but caffeine-sensitive Ca2+ store that can be regulated by intraluminal free Ca2+

1991 • 81 citations

Phosphorylation of the purified cardiac ryanodine receptor by exogenous and endogenous protein kinases

1993 • 79 citations

Competence to Undergo Normal, Fertilization-Induced Cortical Activation Develops after Metaphase I of Meiosis in Mouse Oocytes

1994 • 76 citations

Intraluminal Ca2+ dependence of Ca2+ and ryanodine-mediated regulation of skeletal muscle sarcoplasmic reticulum Ca2+ release.

1992 • 66 citations

Calcium oscillations in parotid acinar cells induced by microsomal Ca(2+)-ATPase inhibition

1992 • 59 citations

A novel ryanodine sensitive calcium release mechanism in cultured human myometrial smooth‐muscle cells

1993 • 40 citations