Prevalence of Activating ras Mutations in Morphologically Characterized Thyroid Nodules

Long-term impact of initial surgical and medical therapy on papillary and follicular thyroid cancer

1994 • 2,638 citations

Tumor Suppressor Genes

1991 • 1,784 citations

Structure of the guanine-nucleotide-binding domain of the Ha-ras oncogene product p21 in the triphosphate conformation

1989 • 881 citations

Follicular Thyroid Cancer Treated at the Mayo Clinic, 1946 Through 1970: Initial Manifestations, Pathologic Findings, Therapy, and Outcome

1991 • 772 citations

Detection of p53 Gene Mutations in Human Brain Tumors by Single-strand Conformation Polymorphism Analysis of Polymerase Chain Reaction Products

1991 • 556 citations

Papillary Thyroid Cancer Treated at the Mayo Clinic, 1946 Through 1970: Initial Manifestations, Pathologic Findings, Therapy, and Outcome

1986 • 510 citations

High frequency of ras oncogene activation in all stages of human thyroid tumorigenesis.

1989 • 414 citations

The rapid detection of unknown mutations in nucleic acids

1993 • 320 citations

Current methods of mutation detection

1993 • 263 citations

Presence of mutations in all three ras genes in human thyroid tumors.

1990 • 250 citations

Activated ras oncogenes in human thyroid cancers.

1988 • 233 citations

Molecular Basis of Thyroid Cancer*

1994 • 232 citations

RasOncogene Mutations in Benign and Malignant Thyroid Neoplasms

1991 • 180 citations

Clonal composition of benign and malignant human thyroid tumors.

1990 • 140 citations

High rates of ras codon 61 mutation in thyroid tumors in an iodide-deficient area.

1991 • 139 citations

Clonality of Thyroid Nodules in Sporadic Goiter

1995 • 116 citations

H-Ras Protooncogene Mutations in Human Thyroid Neoplasms*

1990 • 111 citations

Detection of activated ras oncogenes in human thyroid carcinomas.

1988 • 104 citations

Papillary and follicular thyroid carcinomas show a different pattern of ras oncogene mutation

1989 • 97 citations

Genetic basis of endocrine disease 3: Molecular defects in thyroid gland neoplasia.

1992 • 96 citations

Clonal analysis of human tumors with M27 beta, a highly informative polymorphic X chromosomal probe.

1992 • 94 citations

Mutational activation of RAS and GSP oncogenes in differentiated thyroid cancer and their biological implications

1992 • 92 citations

The clonal origin of thyroid nodules and adenomas.

1989 • 78 citations

Radiation-associated and 'spontaneous' human thyroid carcinomas show a different pattern of ras oncogene mutation.

1991 • 65 citations

Molecular basis of thyroid cancer

1994 • 65 citations

N-ras 61 oncogene mutations in Hürthle cell tumors.

1990 • 38 citations

Genetic basis of endocrine disease 3: Molecular defects in thyroid gland neoplasia

1992 • 37 citations

The value of measurement of RAS oncogenes and nuclear DNA analysis in the diagnosis of Hürthle cell tumors of the thyroid

1992 • 25 citations

Immunohistochemical analysis of the ras oncogene protein product in human thyroid neoplasms.

1988 • 16 citations

Advances in Molecular Biology: Potential Impact on Diagnosis and Treatment of Disorders of the Thyroid

1991 • 6 citations