Computer analysis of DNA and protein sequences

Prediction of protein conformation

1974 • 3,327 citations

On Finding All Suboptimal Foldings of an RNA Molecule

1989 • 2,019 citations

Methods for assessing the statistical significance of molecular sequence features by using general scoring schemes.

1990 • 1,542 citations

Profile analysis: detection of distantly related proteins.

1987 • 1,308 citations

Predicting the secondary structure of globular proteins using neural network models

1988 • 1,243 citations

Improved predictions of secondary structures for RNA.

1989 • 822 citations

Improvements in protein secondary structure prediction by an enhanced neural network

1990 • 708 citations

A tool for multiple sequence alignment.

1989 • 508 citations

Protein secondary structure prediction with a neural network.

1989 • 506 citations

A strategy for the rapid multiple alignment of protein sequences

1987 • 482 citations

Identifying protein-binding sites from unaligned DNA fragments.

1989 • 471 citations

Of urfs and orfs : a primer on how to analyze devised amino acid sequences

1986 • 370 citations

Identification of protein sequence homology by consensus template alignment

1986 • 283 citations

Of URFs and ORFs: A primer on how to analyze derived amino acid sequences

1987 • 276 citations

Prediction of RNA secondary structure, including pseudoknotting, by computer simulation

1990 • 227 citations

Computational Molecular Biology

1999 • 183 citations

Nucleic acid and protein sequence analysis: a practical approach

1988 • 180 citations

Protein secondary structure and homology by neural networks The α‐helices in rhodopsin

1988 • 176 citations

Identification of predictive sequence motifs limited by protein structure data base size

1988 • 160 citations

Sequence Analysis in Molecular Biology: Treasure Trove or Trivial Pursuit

1987 • 128 citations

Flexible protein sequence patterns

1990 • 120 citations

Predicting surface exposure of amino acids from protein sequence

1990 • 116 citations

Prediction of β-turns in proteins using neural networks

1989 • 103 citations

Determination of reliable regions in protein sequence alignments

1990 • 102 citations

Prediction of the disulfide-bonding state of cysteine in proteins

1990 • 101 citations

Sequence analysis in molecular biology; Treasure trove or trivial pursuit

1988 • 82 citations

A method for multiple sequence alignment with gaps

1989 • 80 citations

Protein and Nucleic Acid Sequence Database Searching: A Suitable Case for Parallel Processing

1987 • 72 citations

Neural network detects errors in the assignment of mRNA splice sites

1990 • 63 citations

An object-oriented database for protein structure analysis

1990 • 60 citations

A relational database of protein structures designed for flexible enquiries about conformation

1989 • 58 citations

Relations between protein sequence and structure and their significance

1990 • 54 citations

X chromosome inactivation of the human TIMP gene

1990 • 51 citations

Overview of the LiMB database

1989 • 38 citations

Amino acid sequence templates derived from recurrent turn motifs in proteins: critical evaluation of their predictive power

1989 • 28 citations

COMPUTATIONAL MOLECULAR BIOLOGY

2023 • 19 citations

Getting sense out of sequence data

1988 • 13 citations

Computational biology for biotechnology: Part I

1989 • 4 citations