Analgesic effects of the putative FSH-suppressing gonadal steroid, 3α-hydroxy-4-pregnen-20-one: possible modes of action

Steroid Hormone Metabolites Are Barbiturate-Like Modulators of the GABA Receptor

1986 • 2,194 citations

PHARMACOLOGICAL EFFECTS PRODUCED BY INTRACEREBRAL INJECTION OF DRUGS IN THE CONSCIOUS MOUSE

1957 • 1,523 citations

Multiple Calcium Channels and Neuronal Function

1987 • 1,336 citations

DRUG INTERACTIONS AT THE GABA RECEPTOR-IONOPHORE COMPLEX

1982 • 696 citations

Bicuculline, an antagonist of GABA and synaptic inhibition in the spinal cord of the cat

1971 • 685 citations

Pharmacology of opioids.

1983 • 627 citations

On the specificity of naloxone as an opiate antagonist

1979 • 611 citations

Modulation of the GABA receptor complex by a steroid anaesthetic

1984 • 496 citations

THE ROLE OF ENDOGENOUS OPIATES ON LH SECRETION DURING THE MENSTRUAL CYCLE

1980 • 356 citations

Pregnenolone-sulfate: an endogenous antagonist of the γ-aminobutyric acid receptor complex in brain?

1987 • 329 citations

Anxiolytic activity of an endogenous adrenal steroid

1986 • 317 citations

Actions of Estrogens and Progestins on Nerve Cells

1983 • 261 citations

Intracellular calcium ions decrease the affinity of the GABA receptor

1986 • 255 citations

Opioid receptor types and membrane ion channels

1986 • 248 citations

Modulation of GABA_A receptor activity by alphaxalone

1987 • 196 citations

GABA-dependent modulation of the Cl− ionophore by steroids in rat brain

1987 • 188 citations

The Endocrinology of the Opioids

1985 • 170 citations

THE OPIOID CONTROL OF LH AND FSH RELEASE: EFFECTS OF A MET-ENKEPHALIN ANALOGUE AND NALOXONE

1981 • 165 citations

Effects of sex steroids on brain β-endorphin

1982 • 155 citations

Endogenous opioid peptides and hypothalamic neuroendocrine neurones

1985 • 150 citations

A steroid anesthetic prolongs inhibitory postsynaptic currents in cultured rat hippocampal neurons

1987 • 144 citations

Sleep induction by an adrenal steroid in the rat

1987 • 142 citations

Existence of antiopiate systems as illustrated by MIF-1/Tyr-MIF-1

1986 • 122 citations

Modulation of neurotransmitter action: control of the gamma- aminobutyric acid response through the benzodiazepine receptor

1985 • 121 citations

Analgesic effects of the progesterone metabolite, 3α-hydroxy-5α-pregnan-20-one, and possible modes of action in mice

1987 • 112 citations

Brief exposure to a natural predator, the short-tailed weasel, induces benzodiazepine-sensitive analgesia in white-footed mice

1988 • 105 citations

Neuroendocrine molecular biology

1987 • 103 citations

Locally applied progesterone metabolites alter neuronal responsiveness in the cerebellum

1987 • 102 citations

Calcium agonists and antagonists of the dihydropyridine type: Antinociceptive effects, interference with opiate-?-receptor agonists and neuropharmacological actions in rodents

1986 • 98 citations

Interaction of calcium channel blockers with non-neuronal benzodiazepine binding sites.

1984 • 95 citations

N-methyl bicuculline, a convulsant more potent than bicuculline

1972 • 87 citations

Immunoreactive Beta-Endorphin Concentrations in Brain and Plasma during Pregnancy in Rats: Possible Modulation by Progesterone and Estradiol

1987 • 87 citations

Calcium channel involvement in magnetic field inhibition of morphine-induced analgesia

1987 • 73 citations

The Effect of Naloxone on Endogenous Opioid Regulation of Pituitary Gonadotropins and Prolactin during the Menstrual Cycle*

1984 • 72 citations

Uptake of [³H]Progesterone and [³H]5α-Dihydroprogesterone by Rat Tissues in Vivo and Analysis of Accumulated Radioactivity: Accumulation of 5α-Dihydroprogesterone by Pituitary and Hypothalamic Tissues

1976 • 64 citations

Single unit recording in the midbrain of rats during shock-elicited fighting behavior

1977 • 63 citations

Noncompetitive antagonism of morphine analgesia by diazepam in the formalin test

1986 • 60 citations

Inhibitory influences of FMRFamide and PLG on stress-induced opioid analgesia and activity

1986 • 51 citations

OVARIAN STEROID HORMONES

1985 • 44 citations

Opiate suppression of LH secretion involves central receptors different from those mediating opiate effects on prolactin secretion

1987 • 43 citations

Anterior Pituitary Hormone Responses to a κ-Opioid Agonist in Man

1986 • 42 citations

Effects of morphine on luteinizing hormone secretion and catecholamine turnover in the hypothalamus of estrogen-treated rats

1986 • 39 citations

Is synaptic transmission modulated by progesterone?

1986 • 34 citations

Neuro-Steroids: 3β-Hydroxy-Δ5-Derivatives in the Rat Brain

1986 • 33 citations

Synthesis of the allylic gonadal steroids, 3α-hydroxy-4-pregnen-20-one and 3α-hydroxy-4-androsten-17-one, and of 3α-hydroxy-5α-pregnan-20-one

1985 • 31 citations

Identification of a unique sertoli cell steroid as 3α-hydroxy-4-pregnen-20-one (3α-dihyroprogesterone: 3α-DHP)

1982 • 31 citations

Evidence for intrinsic behavioural activity of the benzodiazepine antagonist, Ro15-1788, in male mice

1983 • 30 citations

Selective Suppression of Follicle-Stimulating Hormone by 3α-Hydroxy-4-Pregnen-20-One, A Steroid Found in Sertoli Cells*

1987 • 29 citations

Inhibitory influences of MIF-1 (PLG) and Tyr-MIF-1 (YPLG) on aggression and defeat-induced analgesia in mice

1986 • 26 citations

Reversal of the antinociceptive effects of centrally-administered morphine by the benzodiazepine receptor antagonist Ro 15-1788

1984 • 24 citations

Steroid-independent endogenous opioid peptide suppression of pulsatile luteinizing hormone release between estrus and diestrus 1 in the rat estrous cycle

1987 • 22 citations

Steroids May Influence Changes in Mood

1986 • 21 citations

The Influence of Chronic Morphine Treatment on the Negative Feedback Regulation of Gonadotropin Secretion by Gonadal Steroids*

1986 • 20 citations

Characterization of the analgesic effects of the benzodiazepine antagonist, Ro 15-1788

1987 • 20 citations

Correlation of the hypnotic potency of benzodiazepines with inhibition of voltage-dependent calcium uptake into mouse brain synaptosomes

1986 • 19 citations

MIF-1 and Tyr-MIF-1 augment GABA-stimulated benzodiazepine receptor binding

1987 • 19 citations

Tyr-MIF-1 augments benzodiazepine receptor binding in vivo

1987 • 18 citations

RO 15-1788 produces naloxone-reversible analgesia in the rat

1988 • 17 citations

Administration of gonadal steroids to neonatal rats affects beta-endorphin levels in the adult

1987 • 14 citations

The possible modulation of morphine analgesia by the supramolecular GABA receptor complex

1986 • 14 citations

Effects of tyr-MIF-1 and MIF-1 at the GABAA receptor chloride channel site

1987 • 11 citations

Role of opioid peptides in pulsatile release of gonadotropins and prolactin in the rat

1987 • 10 citations

Non-competitive antagonism of morphine analgesia by diazepam in the formalin test

1984 • 2 citations