Clinical Pharmacology of 2',3'-Dideoxyinosine in Human Immunodeficiency Virus-Infected Children

3'-Azido-3'-deoxythymidine (BW A509U): an antiviral agent that inhibits the infectivity and cytopathic effect of human T-lymphotropic virus type III/lymphadenopathy-associated virus in vitro.

1985 • 1,830 citations

Inhibition of the in vitro infectivity and cytopathic effect of human T-lymphotrophic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV) by 2',3'-dideoxynucleosides.

1986 • 1,032 citations

Effect of Continuous Intravenous Infusion of Zidovudine (AZT) in Children with Symptomatic HIV Infection

1988 • 452 citations

In Vivo Activity Against HIV and Favorable Toxicity Profile of 2′,3′-Dideoxyinosine

1989 • 426 citations

Mlab — A mathematical modeling tool

1979 • 391 citations

2′,3′-Dideoxyinosine (ddI) in Patients with the Acquired Immunodeficiency Syndrome or AIDS-Related Complex

1990 • 391 citations

Noncompartmental Determination of the Steady-State Volume of Distribution for Any Mode of Administration

1982 • 288 citations

Long-term inhibition of human T-lymphotropic virus type III/lymphadenopathy-associated virus (human immunodeficiency virus) DNA synthesis and RNA expression in T cells protected by 2',3'-dideoxynucleosides in vitro.

1987 • 201 citations

Pharmacokinetics of 2′, 3′-dideoxyadenosine and 2′, 3′-dideoxyinosine in patients with severe human immunodeficiency virus infection

1990 • 133 citations

Effect of continuous-infusion zidovudine therapy on neuropsychologic functioning in children with symptomatic human immunodeficiency virus infection

1990 • 105 citations

The Pharmacokinetics of Zidovudine Administered by Continuous Infusion in Children

1989 • 99 citations

Pharmacokinetics of zidovudine administered intravenously and orally in children with human immunodeficiency virus infection

1989 • 72 citations

Limited sampling model for vinblastine pharmacokinetics.

1987 • 52 citations