Inhibition of Clostridium histolyticum collagenases by phosphonamide peptide inhibitors

On the size of the active site in proteases. I. Papain

1967 • 5,150 citations

A linear equation that describes the steady-state kinetics of enzymes and subcellular particles interacting with tightly bound inhibitors

1972 • 524 citations

A continuous spectrophotometric assay for Clostridium histolyticum collagenase

1981 • 236 citations

Characterization of the individual collagenases from Clostridium histolyticum

1984 • 215 citations

Slow- and fast-binding inhibitors of thermolysin display different modes of binding: crystallographic analysis of extended phosphonamidate transition-state analogs

1987 • 200 citations

Evaluation of Intrinsic Binding Energy from a Hydrogen Bonding Group in an Enzyme Inhibitor

1987 • 174 citations

Purification and separation of individual collagenases of Clostridium histolyticum using red dye ligand chromatography

1984 • 157 citations

Design of potent reversible inhibitors for thermolysin. Peptides containing zinc coordinating ligands and their use in affinity chromatography

1979 • 151 citations

Structures of Two Thermolysin-Inhibitor Complexes That Differ by a Single Hydrogen Bond

1987 • 144 citations

Studies on the Bacillus subtilis neutral-protease- and Bacillus thermoproteolyticus thermolysin-catalyzed hydrolysis of dipeptide substrates

1970 • 131 citations

Phosphonate analogs of carboxypeptidase A substrates are potent transition-state analog inhibitors

1989 • 121 citations

Design of potent and specific inhibitors of carboxypeptidases A and B

1979 • 117 citations

Possible role for water dissociation in the slow binding of phosphorus-containing transition-state-analog inhibitors of thermolysin

1987 • 114 citations

Substrate specificity and kinetic characteristics of angiotensin converting enzyme

1983 • 113 citations

Crystallographic structural analysis of phosphoramidates as inhibitors and transition-state analogs of thermolysin

1986 • 110 citations

Complementary substrate specificities of class I and class II collagenases from Clostridium histolyticum

1985 • 75 citations

Binding energetics of phosphorus-containing inhibitors of thermolysin

1989 • 56 citations

Phosphorus-containing inhibitors of angiotensin-converting enzyme.

1982 • 52 citations

18 The Collagenases

1971 • 50 citations

Inhibition of the collagenase from Clostridium histolyticum by phosphoric and phosphonic amides

1983 • 25 citations

New thiol inhibitors of Clostridium histolyticum collagenase

1988 • 12 citations