Postischemic free radical production in the venous blood of the regionally ischemic swine heart. Effect of deferoxamine.

Spin Trapping: ESR parameters of spin adducts 1474 1528V

1987 • 1,660 citations

Demonstration of free radical generation in "stunned" myocardium of intact dogs with the use of the spin trap alpha-phenyl N-tert-butyl nitrone.

1988 • 691 citations

Measurement of endothelial cell free radical generation: evidence for a central mechanism of free radical injury in postischemic tissues.

1988 • 610 citations

Deleterious effects of oxygen radicals in ischemia/reperfusion. Resolved and unresolved issues.

1989 • 518 citations

Protection against tissue damage in vivo by desferrioxamine: What is its mechanism of action?

1989 • 385 citations

Measurement and characterization of postischemic free radical generation in the isolated perfused heart

1989 • 383 citations

Identification of free radicals in myocardial ischemia/reperfusion by spin trapping with nitrone DMPO

1987 • 357 citations

Production of free radicals and lipid peroxides in early experimental myocardial ischemia

1983 • 288 citations

Improvement of postischemic myocardial function and metabolism induced by administration of deferoxamine at the time of reflow: the role of iron in the pathogenesis of reperfusion injury.

1987 • 249 citations

Spin-trapping evidence that graded myocardial ischemia alters post-ischemic superoxide production

1987 • 205 citations

Conjugated dienes in ischemic and reperfused myocardium: an in vivo chemical signature of oxygen free radical mediated injury

1987 • 152 citations

Lipid Peroxyl Radical Intermediates in the Peroxidation of Polyunsaturated Fatty Acids by Lipoxygenase

1989 • 136 citations

Detection of peroxyl and alkoxyl radicals produced by reaction of hydroperoxides with rat liver microsomal fractions

1989 • 130 citations

The role of neutrophils and free radicals in the ischemic-reperfused heart: Why the confusion and controversy?

1989 • 129 citations

Spin trapping of oxygen and carbon-centered free radicals in ischemic canine myocardium

1987 • 126 citations

Treatment with deferoxamine during ischemia improves functional and metabolic recovery and reduces reperfusion-induced oxygen radical generation in rabbit hearts.

1991 • 124 citations

Decreased defence against free radicals in rat heart during normal reperfusion after hypoxic, ischemic and calcium-free perfusion

1984 • 109 citations

Spin trapping evidence for the lack of significant hydroxyl radical production during the respiration burst of human phagocytes using a spin adduct resistant to superoxide-mediated destruction.

1990 • 93 citations

An electron spin resonance study of the reduction of peroxides by anthracycline semiquinones

1984 • 90 citations

Hydroxyl Radical Production during Oxidative Deposition of Iron in Ferritin

1989 • 87 citations

Heart protection and radical trapping by DMPO during reperfusion in isolated working rat hearts

1990 • 78 citations

Reperfusion-Induced Arrhythmias and Free Radicals

1987 • 71 citations

The cellular-induced decay of DMPO spin adducts of ·OH and ·O2−

1989 • 68 citations

Effects of oxyradicals on oxymyoglobin. Deoxygenation, haem removal and iron release

1989 • 58 citations

Ischemia‐induced changes in myocardial paramagnetic metabolites: Implications for intracellular oxy‐radical generation

1989 • 51 citations

Intracoronary superoxide dismutase for the treatment of “reperfusion injury” A blind randomized placebo-controlled trial in ischemic, reperfused porcine hearts

1988 • 33 citations

Oxygen free radical producing leukocytes cause functional depression of isolated rat hearts: Role of leukotrienes

1990 • 30 citations

Membrane Antioxidants

1988 • 28 citations

Use of 3,3,5,5-tetramethyl-1-pyrroline-1-oxide spin trap for the continuous flow ESR monitoring of hydroxyl radical generation in the ischemic and reperfused myocardium

1989 • 21 citations

Ability of N-tert-butyl alpha phenylnitrone (PBN) to be used in isolated perfused heart spin trapping experiments: Preliminary studies

1988 • 21 citations

Gamma and Pulse Radiolysis Investigation of the Reaction of Desferrioxamine with Superoxide Anions

1989 • 11 citations