A New Concept in the Pharmacology of Neuroprotection

International Union of Pharmacology. XVIII. Nomenclature of receptors for vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide.

1998 • 722 citations

Isolation from Porcine‐Intestinal Wall of a Vasoactive Octacosapeptide Related to Secretin and to Glucagon

1972 • 520 citations

Complete Sequence of a Novel Protein Containing a Femtomolar‐Activity‐Dependent Neuroprotective Peptide

1999 • 367 citations

A femtomolar-acting neuroprotective peptide.

1996 • 255 citations

VIP: Molecular biology and neurobiological function

1989 • 249 citations

Glial Cell Line-Derived Neurotrophic Factor Requires Transforming Growth Factor-β for Exerting Its Full Neurotrophic Potential on Peripheral and CNS Neurons

1998 • 232 citations

Distribution of the mRNA for a pituitary adenylate cyclase-activating polypeptide receptor in the rat brain: An in situ hybridization study

1996 • 210 citations

PACAP Functions as a Neurotrophic Factora

1994 • 178 citations

Vasoactive intestinal peptide prevents excitotoxic cell death in the murine developing brain.

1997 • 174 citations

Activity-dependent neurotrophic factor: structure-activity relationships of femtomolar-acting peptides.

1998 • 125 citations

Norepinephrine and vasoactive intestinal peptide induce IL-6 secretion by astrocytes: Synergism with IL-1β and TNFα

1993 • 124 citations

Neurotrophic factors [activity-dependent neurotrophic factor (ADNF) and basic fibroblast growth factor (bFGF)] interrupt excitotoxic neurodegenerative cascades promoted by a PS1 mutation

1999 • 124 citations

Aging Alters the Rhythmic Expression of Vasoactive Intestinal Polypeptide mRNA But Not Arginine Vasopressin mRNA in the Suprachiasmatic Nuclei of Female Rats

1998 • 120 citations

Protein kinase A-catalyzed phosphorylation of heat shock protein 60 chaperone regulates its attachment to histone 2B in the T lymphocyte plasma membrane

1998 • 113 citations

VIP and PACAP potentiate the action of glutamate on BDNF expression in mouse cortical neurones

1998 • 97 citations

Prevention of activity-dependent neuronal death: Vasoactive intestinal polypeptide stimulates astrocytes to secrete the thrombin-inhibiting neurotrophic serpin, protease nexin I

1996 • 91 citations

Identification of VIP/PACAP receptors on rat astrocytes using antisense oligodeoxynucleotides

1997 • 76 citations

Alterations in the fine structure of nucleoli in sympathetic neurons following NGF-antiserum treatment

1969 • 66 citations

Protection against developmental retardation in apolipoprotein E-deficient mice by a fatty neuropeptide: Implications for early treatment of Alzheimer's disease

1997 • 63 citations

Coordinate Regulation of STAT Signaling and c-fosExpression by the Tyrosine Phosphatase SHP-2

1998 • 62 citations

Activity-dependent neurotrophic factor (ADNF)

1996 • 61 citations

Mapping the active site in vasoactive intestinal peptide to a core of four amino acids: Neuroprotective drug design

1999 • 58 citations

Involvement of Pituitary Adenylate Cyclase‐Activating Polypeptide II Vasoactive Intestinal Peptide 2 Receptor in Mouse Neocortical Astrocytogenesis

1998 • 57 citations

Chronic selective activation of excitatory opioid receptor functions in sensory neurons results in opioid ‘dependence’ without tolerance

1992 • 53 citations

Antiserum to activity-dependent neurotrophic factor produces neuronal cell death in CNS cultures: immunological and biological specificity

1997 • 53 citations

The identification of secreted heat shock 60 -like protein from rat glial cells and a human neuroblastoma cell line

1998 • 53 citations

Vasoactive Intestinal Polypeptide and Pituitary Adenylate Cyclase-Activating Polypeptide Receptor Chimeras Reveal Domains That Determine Specificity of Vasoactive Intestinal Polypeptide Binding and Activation

1997 • 46 citations

A femtomolar-acting neuroprotective peptide induces increased levels of heat shock protein 60 in rat cortical neurons: a potential neuroprotective mechanism

1999 • 45 citations

Spontaneous electrical activity regulates vasoactive intestinal peptide expression in dissociated spinal cord cell cultures

1991 • 44 citations

Ultrastructural Evidence for Combined Action of Noradrenaline and Vasoactive Intestinal Polypeptide Upon Neurons, Astrocytes, and Blood Vessels of the Rat Cerebral Cortex

1998 • 44 citations

Vasoactive Intestinal Peptide Enhances Its Own Expression in Sympathetic Neurons after Injury

1998 • 32 citations

Inhibition of murine embryonic growth by human immunodeficiency virus envelope protein and its prevention by vasoactive intestinal peptide and activity-dependent neurotrophic factor.

1997 • 29 citations

Trimethyltin exposure in the rat induces delayed changes in brain-derived neurotrophic factor, fos and heat shock protein 70.

1997 • 18 citations

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