Preferential uncoupling by manganese of alpha adrenergic receptor mediated inhibition of adenylate cyclase in human platelets

The role of hormone receptors and GTP-regulatory proteins in membrane transduction

1980 • 1,750 citations

Biochemical Properties of Hormone-Sensitive Adenylate Cyclase

1980 • 1,016 citations

Heterogeneity of radioligand binding to alpha-adrenergic receptors. Analysis of guanine nucleotide regulation of agonist binding in relation to receptor subtypes.

1980 • 192 citations

Identification of α-Adrenergic Receptors in Human Platelets by [3H]Dihydroergocryptine Binding

1978 • 186 citations

Characterization of α2-adrenergic receptors on human platelets using [3H]yohimbine

1980 • 166 citations

Agonist-specific effects of guanine nucleotides on alpha-adrenergic receptors in human platelets.

1979 • 155 citations

Inhibition of platelet adenylate cyclase by epinephrine requires GTP

1978 • 123 citations

Unique uncoupling of the frog erythrocyte adenylate cyclase system by manganese. Loss of hormone and guanine nucleotide-sensitive enzyme activities without loss of nucleotide-sensitive, high affinity agonist binding.

1979 • 122 citations

Regulation of human platelet adenylate cyclase by epinephrine, prostaglandin E1, and guanine nucleotides. Evidence for separate guanine nucleotide sites mediating stimulation and inhibition.

1979 • 108 citations

Multiple effects of guanine nucleotides on human platelet adenylate cyclase

1979 • 24 citations