Kinetic properties of ion carriers and channels

Currents carried by sodium and potassium ions through the membrane of the giant axon of Loligo

1952 • 2,384 citations

Nonequilibrium Thermodynamics in Biophysics

1965 • 1,704 citations

Dynamics of ligand binding to myoglobin

1975 • 1,616 citations

Simple Allosteric Model for Membrane Pumps

1966 • 1,271 citations

Temperature-dependent X-ray diffraction as a probe of protein structural dynamics

1979 • 1,136 citations

The potassium permeability of a giant nerve fibre

1955 • 1,094 citations

THE IONIC BASIS OF ELECTRICAL ACTIVITY IN NERVE AND MUSCLE

1951 • 959 citations

Bacteriorhodopsin and the purple membrane of halobacteria

1979 • 909 citations

Ion transfer across lipid membranes in the presence of gramicidin A

1972 • 828 citations

Potassium channels as multi-ion single-file pores.

1978 • 816 citations

Ion-selective electrodes

1982 • 798 citations

The anion transport system of the red blood cell The role of membrane protein evaluated by the use of ‘probes’

1978 • 722 citations

The Gramicidin A Transmembrane Channel: A Proposed π _(L,D) Helix

1971 • 665 citations

Formation of large, ion-permeable membrane channels by the matrix protein (porin) of Escherichia coli

1978 • 515 citations

Ion transfer across lipid membranes in the presence of gramicidin A

1972 • 427 citations

Crystallographic structure studies of an IgG molecule and an Fc fragment

1976 • 416 citations

Ion transport through pores: A rate-theory analysis

1973 • 392 citations

The Gramicidin A Transmembrane Channel: Characteristics of Head-to-Head Dimerized π _(L,D) Helices

1971 • 384 citations

Ionic pores, gates, and gating currents

1974 • 358 citations

Picosecond dynamics of tyrosine side chains in proteins

1979 • 336 citations

Membranes—A series of advances

1974 • 335 citations

Subnanosecond motions of tryptophan residues in proteins

1979 • 325 citations

Transport mechanism of hydrophobic ions through lipid bilayer membranes

1971 • 315 citations

Ionic selectivity of pores formed by the matrix protein (porin) of Escherichia coli

1979 • 293 citations

Channel formation kinetics of gramicidin A in lipid bilayer membranes

1973 • 283 citations

Cyclodepsipeptides as chemical tools for studying ionic transport through membranes

1969 • 279 citations

The Structural Basis of Membrane Function

1976 • 253 citations

The dimeric nature of the gramicidin A transmembrane channel: Conductance and fluorescence energy transfer studies of hybrid channels

1977 • 237 citations

Electrostatic calculations for an ion channel. I. Energy and potential profiles and interactions between ions

1978 • 236 citations

The Rate Constants of Valinomycin-Mediated Ion Transport through Thin Lipid Membranes

1971 • 231 citations

Membrane Transport Processes

1980 • 225 citations

Potential energy barriers to ion transport within lipid bilayers. Studies with tetraphenylborate

1975 • 214 citations

Membrane Transport in Biology

1978 • 193 citations

The transport of potassium through lipid bilayer membranes by the neutral carriers valinomycin and monactin

1971 • 184 citations

Single-channel parameters of gramicidin a,b, and c

1976 • 173 citations

Membrane transduction mechanisms

1979 • 173 citations

Formation of ion channels by a negatively charged analog of gramicidin a

1977 • 160 citations

Contributions to the theory of active transport: II. The gate type non-carrier mechanism and generalizations concerning tracer flow, efficiency, and measurement of energy expenditure

1957 • 153 citations

Testing and characterizing the simple carrier

1974 • 152 citations

Valinomycin-mediated ion transport through neutral lipid membranes: Influence of hydrocarbon chain length and temperature

1973 • 148 citations

Ionic selectivity, saturation, and block in gramicidin a channels

1978 • 145 citations

Conformation of gramicidin A channel in phospholipid vesicles: a 13C and 19F nuclear magnetic resonance study.

1979 • 139 citations

Ionic selectivity, saturation and block in gramicidin A channels:

1977 • 133 citations

Interactions in cation permeation through the gramicidin channel. Cs, Rb, K, Na, Li, Tl, H, and effects of anion binding

1978 • 132 citations

Kinetic analysis of carrier-mediated ion transport by the charge-pulse technique

1976 • 129 citations

Structure of the gramicidin A channel: Discrimination between the π _L,D and the β helix by electrical measurements with lipid bilayer membranes

1977 • 125 citations

A channel mechanism for electrogenic ion pumps

1979 • 123 citations

Dynamic model of globular protein conformations based on NMR studies in solution

1978 • 103 citations

Helical channels in crystals of gramicidin A and of a cesium-gramicidin A complex: an X-ray diffraction study

1978 • 94 citations

Electrostatic calculations for an ion channel. II. Kinetic behavior of the gramicidin A channel

1978 • 94 citations

Influence of sterols on ion transport through lipid bilayer membranes

1978 • 91 citations

Ionic specificity of the gramicidin channel and the thallous ion

1975 • 90 citations

Ion transport in the simplest single file pore

1979 • 83 citations

Influence of membrane structure on the kinetics of carrier-mediated ion transport through lipid bilayers

1977 • 77 citations

The malonyl gramicidin channel: NMR-derived rate constants and comparison of calculated and experimental single-channel currents

1980 • 73 citations

The Present State of the Carrier Hypothesis

1975 • 70 citations

Interaction of cation fluxes in gramicidin A channels in lipid bilayer membranes

1978 • 69 citations

Rate theory calculation of gramicidin single-channel currents using NMR-derived rate constants.

1980 • 66 citations

Alkali ion transport through lipid bilayer membranes mediated by enniatin A and B and beauvericin

1978 • 65 citations

THE KINETIC AND EQUILIBRIUM COMPONENTS OF SELECTIVE IONIC PERMEABILITY MEDIATED BY NACTINAND VALINOMYCIN‐TYPE CARRIERS HAVING SYSTEMATICALLY VARIED DEGREES OF METHYLATION^fn1

1975 • 59 citations

A general kinetic analysis of transport Tests of the carrier model based on predicted relations among experimental parameters

1979 • 57 citations

A model for sugar transport across red cell membranes without carriers

1970 • 54 citations

Ion movement through gramicidin A channels. On the importance of the aqueous diffusion resistance and ion-water interactions.

1980 • 54 citations

Complex formation of monovalent cations with biofunctional ligands

2007 • 47 citations

Testing and characterizing the simple pore

1974 • 47 citations

BASIC ASPECTS OF CALCIUM CHEMISTRY AND MEMBRANE INTERACTION: ON THE MESSENGER ROLE OF CALCIUM*

1978 • 42 citations

Zur Theorie der „Single File“-Diffusion, II

1965 • 38 citations

Complex formation of monovalent cations with biofunctional ligands

2007 • 37 citations

Rectification phenomena in carrier-mediated ion transport

1973 • 31 citations

MECHANISM OF CARRIER TRANSPORT AND THE ADP, ATP CARRIER

1976 • 31 citations

Theory of transport noise in membrane channels with open-closed kinetics

1979 • 27 citations

Ionic interactions in the potassium channel of squid giant axons

1977 • 23 citations

Iion transport through the potassium channels of biological membranes

1977 • 11 citations

Studies on the Gramicidin Channel

1977 • 11 citations

A Single-File Model for Potassium Transport in Squid Giant Axon

1977 • 10 citations