Multiple actions of arylalkylamine arthropod toxins on theN-methyl-d-aspartate receptor

Magnesium gates glutamate-activated channels in mouse central neurones

1984 • 3,999 citations

Voltage-dependent block by Mg2+ of NMDA responses in spinal cord neurones

1984 • 2,822 citations

Ionic Blockage of Sodium Channels in Nerve

1973 • 1,590 citations

Requirement for Glycine in Activation of NMDA-Receptors Expressed in Xenopus Oocytes

1988 • 1,415 citations

Block of N-methyl-D-aspartate-activated current by the anticonvulsant MK-801: selective binding to open channels.

1988 • 747 citations

Switch in glutamate receptor subunit gene expression in CA1 subfield of hippocampus following global ischemia in rats.

1992 • 399 citations

GYKI 52466, a 2,3-benzodiazepine, is a highly selective, noncompetitive antagonist of AMPA/kainate receptor responses

1993 • 359 citations

Splice variants of the N-methyl-D-aspartate receptor NR1 identify domains involved in regulation by polyamines and protein kinase C.

1993 • 347 citations

Modulation of excitatory amino acid receptors by group IIB metal cations in cultured mouse hippocampal neurones.

1989 • 275 citations

Kainate-induced status epilepticus alters glutamate and GABAA receptor gene expression in adult rat hippocampus: an in situ hybridization study

1994 • 271 citations

A single amino acid determines the subunit-specific spider toxin block of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate/kainate receptor channels.

1993 • 243 citations

Sensitivity of the N-methyl-D-aspartate receptor to polyamines is controlled by NR2 subunits.

1994 • 219 citations

Structure and synthesis of a potent glutamate receptor antagonist in wasp venom.

1988 • 201 citations

Modulation of N‐methyl‐D‐aspartic acid receptor desensitization by glycine in mouse cultured hippocampal neurones.

1990 • 199 citations

Multiple effects of spermine on N‐methyl‐D‐aspartic acid receptor responses of rat cultured hippocampal neurones.

1993 • 199 citations

Argiotoxin detects molecular differences in AMPA receptor channels

1993 • 186 citations

Histamine potentiates N-methyl-d-aspartate responses in acutely isolated hippocampal neurons

1993 • 179 citations

Spider toxins as tools for dissecting elements of excitatory amino acid transmission

1988 • 165 citations

Polyamines potentiate responses of N-methyl-D-aspartate receptors expressed in xenopus oocytes.

1990 • 142 citations

A single amino acid determines the subunit-specific spider toxin block of α-amino-3-hydroxy-5-methylisoxazole-4-propionate/kainate receptor channels.

1993 • 118 citations

Spermine potentiation of recombinant N-methyl-D-aspartate receptors is affected by subunit composition.

1994 • 112 citations

Spermine regulates N-methyl-d-aspartate receptor desensitization

1992 • 110 citations

Switch in glutamate receptor subunit gene expression in CA1 subfield of hippocampus following global ischemia in rats

1993 • 104 citations

Selective antagonism of native and cloned kainate and NMDA receptors by polyamine-containing toxins.

1993 • 103 citations

Structures and biological activities of three synaptic antagonists from orb weaver spider venom

1987 • 98 citations

Multiple structural determinants of voltage-dependent magnesium block in recombinant NMDA receptors

1993 • 97 citations

Antagonism of responses to excitatory amino acids on rat cortical neurones by the spider toxin, argiotoxin₆₃₆

1989 • 93 citations

Spermine and philanthotoxin potentiate excitatory amino acid responses of Xenopus oocytes injected with rat and chick brain RNA

1990 • 91 citations

Down‐Regulation of AMPA Receptor Subunit GluR2 in Amygdaloid Kindling

1995 • 88 citations

Mechanisms influencing stimulatory effects of spermine at recombinant N-methyl-D-aspartate receptors.

1994 • 74 citations

Subunit-specific potentiation of recombinant N-methyl-D-aspartate receptors by histamine.

1994 • 72 citations

Spider toxin blocks excitatory amino acid responses in isolated hippocampal pyramidal neurons

1987 • 65 citations

Diversity of glutamate receptor subunit mRNA expression within live hippocampal CA1 neurons.

1993 • 62 citations

Subunit‐specific block of cloned NMDA receptors by argiotoxin₆₃₆

1993 • 54 citations

Inhibition of rat brain glutamate receptors by philanthotoxin.

1989 • 53 citations

Philanthotoxin blocks quisqualate‐, AMPA‐ and kainate‐, but not NMDA‐, induced excitation of rat brainstem neurones in vivo

1990 • 33 citations

Hydrophobic interactions of n-alkyl diamines with the N-methyl-D-aspartate receptor: voltage-dependent and -independent blocking sites.

1994 • 31 citations

Argiotoxin636 inhibits NMDA-activated ion channels expressed in Xenopus oocytes

1991 • 25 citations

Spermine reciprocally changes the affinity of NMDA receptor agonists and antagonists

1991 • 23 citations

Arylamine spider toxins antagonize NMDA receptor‐mediated synaptic transmission in rat hippocampal slices

1991 • 23 citations

Neuroreceptors, ion channels and the brain

1992 • 15 citations

The anticonvulsant (±)-5-aminocarbonyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine (ADCI) selectively blocks NMDA-activated current in cultured rat hippocampal neurones: Kinetic analysis and comparison with dizocilpine

1992 • 14 citations

1,10-Diaminodecane and 1,12-diaminododecane block NMDA receptor currents by an open channel mechanism

1992 • 12 citations

Philanthotoxin-343 blocks long-term potentiation in rat hippocampus

1992 • 9 citations

Effects of philathotoxin-343 on CA1 pyramidal neurons of rat hippocampus in vitro

1992 • 7 citations