Mapping of resection margins of oral cancer for p53 overexpression and chromosome instability to detect residual (pre)malignant cells

p53 Mutations in Human Cancers

1991 • 8,133 citations

The Clonal Evolution of Tumor Cell Populations

1976 • 6,310 citations

Genetic instabilities in human cancers

1998 • 4,165 citations

Mutations of mitotic checkpoint genes in human cancers

1998 • 1,482 citations

Mutator phenotype may be required for multistage carcinogenesis.

1991 • 1,327 citations

The p53 pathway

1999 • 1,322 citations

Abnormal Centrosome Amplification in the Absence of p53

1996 • 802 citations

Molecular Assessment of Histopathological Staging in Squamous-Cell Carcinoma of the Head and Neck

1995 • 759 citations

A p53-Dependent Mouse Spindle Checkpoint

1995 • 668 citations

Hierarchical order in chromosome-specific human alpha satellite DNA

1987 • 510 citations

The significance of “positive” margins in surgically resected epidermoid carcinomas

1978 • 368 citations

Activation of p53 gene expression in premalignant lesions during head and neck tumorigenesis.

1994 • 272 citations

Current Protocols In Cytometry

1997 • 210 citations

Detection of numerical chromosome aberrations using in situ hybridization in paraffin sections of routinely processed bladder cancers.

1991 • 207 citations

Expression of mutated p53 occurs in tumor-distant epithelia of head and neck cancer patients: a possible molecular basis for the development of multiple tumors.

1993 • 200 citations

TP53 DNA contact mutations are selectively associated with allelic loss and have a strong clinical impact in head and neck cancer

1998 • 156 citations

Squamous cell carcinoma of the oropharynx: Why we fail

1976 • 143 citations

Increased polysomies of chromosomes 7 and 17 during head and neck multistage tumorigenesis.

1993 • 134 citations

Supraomohyoid Neck Dissection in the Treatment of Head and Neck Tumors: Survival Results in 212 Cases

1993 • 132 citations

Common patterns of genetic evolution in human solid tumors

1997 • 115 citations

Distinct nonrandom patterns of chromosomal aberrations in the progression of squamous cell carcinomas of the head and neck.

1995 • 66 citations

p53 is overexpressed in fifty percent of pre-invasive lesions of head and neck epithelium

1994 • 59 citations

Chromosome Instability as an Indicator of Malignant Progression in Laryngeal Mucosa

2000 • 53 citations

Genetic instability leads to loss of both p53 alleles in a human glioblastoma

1998 • 44 citations

Processing and Staining of Cell and Tissue Material for Interphase Cytogenetics

1998 • 25 citations

Double-target fluorescence in situ hybridization distinguishes multiple genetically aberrant clones in head and neck squamous cell carcinoma

1998 • 16 citations