Evaluation of PTEN expression in cervical adenocarcinoma by tissue microarray

PTEN , a Putative Protein Tyrosine Phosphatase Gene Mutated in Human Brain, Breast, and Prostate Cancer

1997 • 4,753 citations

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

1997 • 2,746 citations

Negative Regulation of PKB/Akt-Dependent Cell Survival by the Tumor Suppressor PTEN

1998 • 2,505 citations

Inhibition of Cell Migration, Spreading, and Focal Adhesions by Tumor Suppressor PTEN

1998 • 1,215 citations

The lipid phosphatase activity of PTEN is critical for its tumor supressor function

1998 • 1,180 citations

Loss of PTEN expression in paraffin-embedded primary prostate cancer correlates with high Gleason score and advanced stage.

1999 • 631 citations

Pten and p27KIP1 cooperate in prostate cancer tumor suppression in the mouse

2001 • 495 citations

The epidemiology of endometrial cancer

1991 • 403 citations

The phosphoinositol phosphatase activity of PTEN mediates a serum-sensitive G1 growth arrest in glioma cells.

1998 • 393 citations

PTEN gene mutations are seen in high-grade but not in low-grade gliomas.

1997 • 383 citations

Immunohistochemical Evidence of Loss of PTEN Expression in Primary Ductal Adenocarcinomas of the Breast

1999 • 381 citations

PTEN Interactions with Focal Adhesion Kinase and Suppression of the Extracellular Matrix-dependent Phosphatidylinositol 3-Kinase/Akt Cell Survival Pathway

1999 • 367 citations

Mutations of the human PTEN gene

2000 • 323 citations

Molecular identification of latent precancers in histologically normal endometrium.

2001 • 200 citations

PTEN Gene and Integrin Signaling in Cancer

1999 • 186 citations

Combined loss of PTEN and p27 expression is associated with tumor cell proliferation by Ki-67 and increased risk of recurrent disease in localized prostate cancer.

2003 • 171 citations

Distinction Between Endometrial and Endocervical Adenocarcinoma: An Immunohistochemical Study

2002 • 162 citations

Changes in EndometrialPTENExpression throughout the Human Menstrual Cycle¹

2000 • 129 citations

Involvement of PTEN mutations in the genetic pathways of colorectal cancerogenesis

2000 • 125 citations

Recent advances in immunohistochemistry in gynaecological pathology

2002 • 115 citations

Diagnosis of premalignant endometrial disease

2002 • 102 citations

Changes in Endometrial PTEN Expression throughout the Human Menstrual Cycle

2000 • 93 citations

Endocervical glandular lesions: controversial aspects and ancillary techniques

2003 • 83 citations

Genetic Pathways of Colorectal Carcinogenesis Rarely Involve thePTEN and LKB1 Genes Outside the Inherited Hamartoma Syndromes

1998 • 79 citations

Mutation of the PTEN gene in advanced cervical cancer correlated with tumor progression and poor outcome after radiotherapy

2001 • 60 citations

Cell Cycle Arrest by the PTEN Tumor Suppressor Is Target Cell Specific and May Require Protein Phosphatase Activity

2000 • 57 citations

Tumor suppressor gene alterations in malignant gliomas: histopathological associations and prognostic evaluation.

1999 • 47 citations

Allelotype and replication error phenotype of small cell lung carcinoma

1997 • 38 citations

Allele loss in colorectal cancer at the Cowden disease/Juvenile Polyposis locus on 10q

1997 • 36 citations

PTEN expression is maintained in sporadic colorectal tumours

2001 • 32 citations

Association of PTEN mutation with HPV-negative adenocarcinoma of the uterine cervix

2004 • 14 citations