Crystal structure of a deletion mutant of a tyrosyl-tRNA synthetase complexed with tyrosine

The interpretation of protein structures: Estimation of static accessibility

1971 • 5,771 citations

A graphics model building and refinement system for macromolecules

1978 • 1,858 citations

Hydrogen bonding and biological specificity analysed by protein engineering

1985 • 1,050 citations

Stereochemical Criteria for Polypeptide and Protein Chain Conformations

1965 • 715 citations

Computational crystallography

2012 • 705 citations

Molecular Replacement Method

1972 • 468 citations

Biological Macromolecules and Assemblies

1987 • 400 citations

The frequency of errors in protein biosynthesis

1972 • 396 citations

Methods and programs for direct-space exploitation of geometric redundancies

1976 • 383 citations

Computing in Crystallography

1981 • 303 citations

Mistranslation in E. coli

1977 • 284 citations

A structure-factor least-squares refinement procedure for macromolecular structures using constrainedandrestrained parameters

1977 • 250 citations

A new least-squares refinement technique based on the fast Fourier transform algorithm

1978 • 193 citations

Enzyme hyperspecificity. Rejection of threonine by the valyl-tRNA synthetase by misacylation and hydrolytic editing

1976 • 192 citations

The Catalytic Properties of Tyrosyl Ribonucleic Acid Synthetases from Escherichia coli and Bacillus subtilis^*

1966 • 178 citations

Tyrosyl-tRNA synthetase forms a mononucleotide-binding fold

1982 • 149 citations

A model of synthetase/transfer RNA interaction as deduced by protein engineering

1986 • 117 citations

The Amino Acid Sequence of the Tyrosy1-tRNA Synthetase from Bacillus stearothermophilus

1983 • 112 citations

The crystal structure of tyrosyl-transfer RNA synthetase at 2.7 Å resolution

1976 • 109 citations

Analysis of Enzyme Structure and Activity by Protein Engineering

1984 • 97 citations

Tyrosyl-tRNA synthetase from Escherichia coli. Stoichiometry of ligand binding and half-of-the-sites reactivity in aminoacylation

1975 • 91 citations

Probing histidine-substrate interactions in tyrosyl-tRNA synthetase using asparagine and glutamine replacements

1985 • 88 citations

Deletion mutagenesis using an ‘M13 splint’: the N-terminal structural domain of tyrosyl-tRNA synthetase (B. stearothermophilus) catalyses the formation of tyrosyl adenylate.

1983 • 82 citations

Hydrogen bonding in enzymatic catalysis analysed by protein engineering

1985 • 78 citations

Refinement of a molecular model for lamprey hemoglobin from Petromyzon marinus

1985 • 78 citations

A method for refinement of partially interpreted protein structures including a procedure for scaling between a model and an electron-density map

1983 • 66 citations

Transformations to optimize the superposition of similar structures

1979 • 62 citations

Binding of tyrosine, adenosine triphosphate and analogues to crystalline tyrosyl transfer RNA synthetase

1978 • 59 citations

Reversible dissociation of dimeric tyrosyl-tRNA synthetase by mutagenesis at the subunit interface

1985 • 54 citations

Tyrosyl transfer ribonucleic acid synthetase from Escherichia coli B. Analysis of tyrosine and adenosine 5'-triphosphate binding sites

1973 • 26 citations

Interaction of crystalline tyrosyl-tRNA synthetase with adenosine, adenosine monophosphate, adenosine triphosphate and pyrophosphate in the presence of tyrosinol

1984 • 14 citations

Crystallographic relationship between human and hen-egg lysozymes. I. Methods for the establishment of molecular orientational and positional parameters

1976 • 13 citations

The application of the molecular replacement method in studies on the quaternary structure of haemoglobin

1981 • 7 citations