Longitudinal study of cerebrospinal fluid amyloid proteins and apolipoprotein E in patients with probable Alzheimer's disease

Clinical diagnosis of Alzheimer's disease

1984 • 27,279 citations

Association of apolipoprotein E allele ϵ4 with late‐onset familial and sporadic Alzheimer's disease

1993 • 3,693 citations

Isolation and quantification of soluble Alzheimer's β-peptide from biological fluids

1992 • 1,701 citations

Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease.

1993 • 1,480 citations

Reduction of β‐amyloid peptide₄₂ in the cerebrospinal fluid of patients with Alzheimer's disease

1995 • 684 citations

The Lack of Accumulation of Senile Plaques or Amyloid Burden in Alzheimerʼs Disease Suggests a Dynamic Balance Between Amyloid Deposition and Resolution

1993 • 269 citations

Utility of extrapyramidal signs and psychosis as predictors of cognitive and functional decline, nursing home admission, and death in Alzheimer's disease

1994 • 229 citations

Blot hybridisation analysis of genomic DNA.

1984 • 224 citations

Association of apolipoprotein E genotype with brain levels of apolipoprotein E and apolipoprotein J (clusterin) in Alzheimer disease

1995 • 215 citations

Decreased levels of soluble amyloid beta-protein precursor in cerebrospinal fluid of live Alzheimer disease patients.

1992 • 209 citations

Soluble derivatives of the β amyloid protein precursor in cerebrospinal fluid

1990 • 105 citations

Amyloid β protein levels in cerebrospinal fluid are elevated in early‐onset Alzheimer's disease

1994 • 102 citations

Assessment of Amyloid β Protein in Cerebrospinal Fluid as an Aid in the Diagnosis of Alzheimer's Disease

1996 • 93 citations

Soluble amyloid β-protein in the cerebrospinal fluid from patients with Alzheimer's disease, vascular dementia and controls

1994 • 74 citations

Cerebrospinal fluid apolipoprotein E (apoE) levels in Alzheimer's disease patients are increased at follow up and show a correlation with levels of tau protein

1997 • 57 citations

Altered apolipoprotein E secretion in cytokine treated human astrocyte cultures

1997 • 56 citations

Apolipoprotein E in Cerebrospinal Fluid in 85-Year-Old Subjects

1997 • 35 citations

An Age-Related Correlation between Levels of β-Amyloid Precursor Protein and β-Amyloid in Human Cerebrospinal Fluid

1995 • 11 citations