Photocleavage of DNA and photofootprinting of E.coli RNA polymerase bound to promoter DNA by azido-9-acridinylamines

A rapid alkaline extraction procedure for screening recombinant plasmid DNA

1979 • 15,511 citations

DNAase footprinting a simple method for the detection of protein-DNA binding specificity

1978 • 2,092 citations

Procedure for the rapid, large-scale purification of Escherichia coli DNA-dependent RNA polymerase involving polymin P precipitation and DNA-cellulose chromatography

1975 • 1,157 citations

Design of Sequence-Specific DNA-Binding Molecules

1986 • 840 citations

PSORALENS AS PHOTOACTIVE PROBES OF NUCLEIC ACID STRUCTURE AND FUNCTION: ORGANIC CHEMISTRY, PHOTOCHEMISTRY, AND BIOCHEMISTRY

1985 • 749 citations

Footprinting DNA-protein complexes in situ following gel retardation assays using 1,10-phenanthroline-copper ion: Escherichia coli RNA polymerase-lac promoter complexes

1987 • 312 citations

Polyfunctional DNA intercalating agents

1986 • 190 citations

Use of light for footprinting DNA in vivo

1984 • 181 citations

DNA-binding site of lac repressor probed by dimethylsulfate methylation of lac operator

1979 • 177 citations

Methidiumpropyl-EDTA-Fe(II) and DNase I footprinting report different small molecule binding site sizes on DNA

1983 • 175 citations

Nuclease activity of 1,10-phenanthroline-copper ion. Conformational analysis and footprinting of the lac operon

1985 • 173 citations

Changes in the DNA structure of the lac UV5 promoter during formation of an open complex with Escherichia coli RNA polymerase

1985 • 125 citations

Photofootprinting in vivo detects transcription-dependent changes in yeast TATA boxes

1987 • 117 citations

Sequence context effects on 8-methoxypsoralen photobinding to defined DNA fragments

1987 • 117 citations

Regulation of the deo operon in Escherichia coli

1978 • 76 citations

The structure of tandem regulatory regions in the deo operon of Escherichia coli K12

1982 • 76 citations

Promoter search by Escherichia coli RNA polymerase on a circular DNA template.

1987 • 64 citations

Site specificity of psoralen-DNA interstrand cross-linking determined by nuclease Bal31 digestion

1986 • 53 citations

Entwicklungen in der Arylnitren-Chemie: Synthesen und Mechanismen

1979 • 51 citations

Sequence-influenced interactions of oligoacridines with DNA detected by retarded gel electrophoretic migrations

1988 • 45 citations

Visualization of the movement of the Escherichia coli RNA polymerase along the Lac UV5 promoter during the initiation of the transcription

1986 • 43 citations

Synthesis, DNA-binding and biological activity of a double intercalating analog of ethidium bromide

1978 • 37 citations

Adenosine-guanosine preferential photocleavage of DNA by azido-benzoyl- and diazocyclopenta-dienylcarbonyloxy derivatives of 9-aminoacridine

1988 • 37 citations

Ethidium binding sites on plasmid DNA determined by photoaffinity labeling.

1984 • 24 citations

Photoaffinity Labeling of Chromatin

1982 • 18 citations

Photochemical cross-linking of protein and DNA in chromatin. Synthesis and application of a photosensitive cleavable derivative of 9-aminoacridine with two photoprobes connected through a disulphide-containing linker

1984 • 15 citations

Photoaffinity labelling of submitochondrial membranes with the 3-azido analogue of 9-amino-3-chloro-7-methoxyacridine

1985 • 11 citations

Photochemical crosslinking of protein and DNA in chromatin

1985 • 7 citations

A stopped-flow apparatus for photoaffinity labeling studies in the milliseconds time range. Application in investigations of the nicotinic acetylcholine receptor

1986 • 4 citations