Multivesicular Bodies and Multivesicular Endosomes: The "Ins and Outs" of Endosomal Traffic

Receptor-mediated endocytosis of transferrin and recycling of the transferrin receptor in rat reticulocytes.

1983 • 1,586 citations

Ubiquitin-Dependent Sorting into the Multivesicular Body Pathway Requires the Function of a Conserved Endosomal Protein Sorting Complex, ESCRT-I

2001 • 1,373 citations

c-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor

1998 • 865 citations

A single motif responsible for ubiquitin recognition and monoubiquitination in endocytic proteins

2002 • 626 citations

TCR Activation of Human T Cells Induces the Production of Exosomes Bearing the TCR/CD3/ζ Complex

2002 • 624 citations

Hrs Regulates Endosome Membrane Invagination and Tyrosine Kinase Receptor Signaling in Drosophila

2002 • 431 citations

Ubiquitination and proteasomal activity is required for transport of the EGF receptor to inner membranes of multivesicular bodies

2002 • 378 citations

Sorting of proteins into multivesicular bodies: ubiquitin-dependent and -independent targeting

2001 • 324 citations

A mutant EGF-receptor defective in ubiquitylation and endocytosis unveils a role for Grb2 in negative signaling

2002 • 280 citations

The Tetraspanin CD63/lamp3 Cycles between Endocytic and Secretory Compartments in Human Endothelial Cells

2000 • 276 citations

Mammalian class E vps proteins recognize ubiquitin and act in the removal of endosomal protein–ubiquitin conjugates

2002 • 264 citations

Multivesicular Bodies Are an Intermediate Stage in the Formation of Platelet α-Granules

1998 • 235 citations

Hrs Interacts with Sorting Nexin 1 and Regulates Degradation of Epidermal Growth Factor Receptor

2001 • 190 citations

Deubiquitination Step in the Endocytic Pathway of Yeast Plasma Membrane Proteins: Crucial Role of Doa4p Ubiquitin Isopeptidase

2001 • 157 citations

AP-3 Mediates Tyrosinase but Not TRP-1 Trafficking in Human Melanocytes

2001 • 149 citations

Endocytosis and mitogenic signaling

1999 • 131 citations

EGF receptor residues Leu679, Leu680 mediate selective sorting of ligand-receptor complexes in early endosomal compartments

2000 • 66 citations

The Cbl Family: Ubiquitin Ligases Regulating Signaling by Tyrosine Kinases

2001 • 64 citations

Membrane Traffic

2001 • 46 citations

Resistance Is Futile

2001 • 46 citations

EGF receptor downregulation depends on a trafficking motif in the distal tyrosine kinase domain

2002 • 36 citations

The Cbl Family: Ubiquitin Ligases Regulating Signaling by Tyrosine Kinases

2001 • 10 citations