Electrostatic interactions in the assembly of haemoglobin

Stereochemistry of Cooperative Effects in Haemoglobin: Haem–Haem Interaction and the Problem of Allostery

1970 • 2,874 citations

Isoelectric points and molecular weights of proteins

1976 • 520 citations

Thalassemia Syndromes

2009 • 476 citations

A New Method for the Preparation of α and β Subunits of Human Hemoglobin

1965 • 453 citations

The properties and interactions of the isolated α and β chains of human haemoglobin

1965 • 141 citations

Molecular and cellular pathogenesis of hemoglobin SC disease.

1982 • 109 citations

Thermodynamic studies on subunit assembly in human hemoglobin. Self-association of oxygenated chains (alphaSH and betaSH): determination of stoichiometries and equilibrium constants as a function of temperature.

1977 • 104 citations

Differences in spectra of alpha and beta chains of hemoglobin between isolated state and in tetramer.

1975 • 82 citations

Differences in Affinity of Variant β Chains for a Chains: A Possible Explanation for the Variation in the Percentages of β Chain Variants in Heterozygotes

1977 • 69 citations

Imbalanced globin chain synthesis in heterozygous beta-thalassemic bone marrow.

1975 • 65 citations

Acute nonlymphocytic leukemia with basophilic differentiation

1982 • 58 citations

Intracellular Loss of Free α Chains in β Thalassaemia

1969 • 54 citations

Proteolytic activity in erythrocyte precursors

1978 • 52 citations

Competition of normal β chains and sickle haemoglobin β chains for α chains as a post-translational control mechanism

1978 • 52 citations

The Effect of pH on the Rates of Ligand Replacement Reactions of Human Adult and Fetal Hemoglobins and Their Subunits

1972 • 50 citations

Self-association of hemoglobin β ^SH chains is linked to oxygenation

1978 • 44 citations

Homos and Heteros among the Hemos

1974 • 42 citations

Thalassemia Syndromes

2014 • 28 citations

Association-dependent absorption spectra of oxyhemoglobin A and its subunits.

1981 • 24 citations

Enhanced quaternary stability of β4 hemoglobin in 2 m-sodium chloride

1973 • 24 citations

Evidence for a difference in affinities of human hemoglobin beta A and beta S chains for alpha chains.

1980 • 23 citations

Assembly of human adult and sickle hemoglobins from their oxygenated subunits. Differential rates of beta chain tetramer dissociation.

1981 • 20 citations

Percentages of abnormal hemoglobins in adults with a heterozygosity for an α‐chain and/or a β‐chain variant

1983 • 17 citations

Excess alpha chains are lost from beta-thalassemic reticulocytes by proteolysis.

1981 • 16 citations

The oxygen affinity of hemoglobin βSH chains is concentration dependent

1978 • 14 citations

Rapid destruction of newly synthesized excess beta-globin chains in HbH disease

1981 • 14 citations

Heterotropic interactions in monomeric βSH chains from human hemoglobin

1981 • 10 citations

Rapid proteolysis of unstable globins in human bone marrow

1983 • 6 citations

The effect of pH on the rate of dissociation of the oxygenated beta chain tetramer of Hb A

1983 • 4 citations