Low molecular weight heparin in pregnancy: current issues

International consensus statement on preliminary classification criteria for definite antiphospholipid syndrome: Report of an International workshop

1999 • 2,708 citations

Low-Molecular-Weight Heparin versus a Coumarin for the Prevention of Recurrent Venous Thromboembolism in Patients with Cancer

2003 • 2,435 citations

Heparin-Induced Thrombocytopenia in Patients Treated with Low-Molecular-Weight Heparin or Unfractionated Heparin

1995 • 2,330 citations

Antithrombotic Therapy for Venous Thromboembolic Disease

2001 • 2,108 citations

Low-Molecular-Weight Heparins

1997 • 1,529 citations

Randomised controlled trial of aspirin and aspirin plus heparin in pregnant women with recurrent miscarriage associated with phospholipid antibodies (or antiphospholipid antibodies)

1997 • 1,090 citations

Thrombophilic disorders and fetal loss: a meta-analysis

2003 • 861 citations

Increased frequency of genetic thrombophilia in women with complications of pregnancy

1999 • 826 citations

Antiphospholipid antibody–associated recurrent pregnancy loss: Treatment with heparin and low-dose aspirin is superior to low-dose aspirin alone

1996 • 807 citations

Different Intensities of Oral Anticoagulant Therapy in the Treatment of Proximal-Vein Thrombosis

1982 • 753 citations

Anticoagulation of Pregnant Women With Mechanical Heart Valves

2000 • 742 citations

Use of Antithrombotic Agents During Pregnancy

1995 • 682 citations

Low-molecular-weight heparin versus standard heparin in general and orthopaedic surgery: a meta-analysis

1992 • 679 citations

Heparin prevents antiphospholipid antibody–induced fetal loss by inhibiting complement activation

2004 • 663 citations

Increased fetal loss in women with heritable thrombophilia

1996 • 654 citations

Heparin-induced Thrombocytopenia: Towards Consensus

1998 • 555 citations

Safety of Low-Molecular-Weight Heparin in Pregnancy: A Systematic Review

1999 • 554 citations

Dose-dependent fetal complications of warfarin in pregnant women with mechanical heart valves

1999 • 488 citations

Adjusted Subcutaneous Heparin versus Warfarin Sodium in the Long-Term Treatment of Venous Thrombosis

1982 • 445 citations

Antiphospholipid syndrome in pregnancy: a randomized, controlled trial of treatment

2002 • 437 citations

Low-molecular-weight heparin versus low-dose aspirin in women with one fetal loss and a constitutional thrombophilic disorder

2004 • 397 citations

Treatment of deep venous thrombosis with low-molecular-weight heparins. A meta-analysis

1995 • 386 citations

Low-Molecular-Weight Heparin Compared with Intravenous Unfractionated Heparin for Treatment of Pulmonary Embolism

2004 • 384 citations

Low molecular weight heparin in prevention of perioperative thrombosis.

1992 • 384 citations

Osteoporotic fractures and the recurrence of thromboembolism during pregnancy and the puerperium in 184 women undergoing thromboprophylaxis with heparin

1993 • 381 citations

Low-molecular-weight heparins and unfractionated heparin in the treatment of patients with acute venous thromboembolism: Results of a meta-analysis

1996 • 378 citations

Subcutaneous Enoxaparin Once or Twice Daily Compared with Intravenous Unfractionated Heparin for Treatment of Venous Thromboembolic Disease

2001 • 367 citations

Comparison of efficacy and safety of low molecular weight heparins and unfractionated heparin in initial treatment of deep venous thrombosis: a meta-analysis

1994 • 306 citations

Does aspirin have a role in improving pregnancy outcome for women with the antiphospholipid syndrome? A randomized controlled trial

2000 • 287 citations

Histopathological findings in placentae from patients with intra-uterine fetal death and anti-phospholipid antibodies

1991 • 278 citations

Postpartum Bone Mineral Density in Women Treated for Thromboprophylaxis with Unfractionated Heparin or LMW Heparin

2002 • 276 citations

A Comparison of Two Different Prophylactic Dose Regimens of Low Molecular Weight Heparin in Bariatric Surgery

2002 • 274 citations

A prospective study of heparin-induced osteoporosis in pregnancy using bone densitometry

1994 • 273 citations

Venous thromboembolism during pregnancy: a retrospective study of enoxaparin safety in 624 pregnancies

2001 • 272 citations

Use of Antithrombotic Agents During Pregnancy

2001 • 271 citations

Recurrent pregnancy loss with antiphospholipid antibody: a systematic review of therapeutic trials

2002 • 267 citations

Treatment of Deep Venous Thrombosis With Low-Molecular-Weight Heparins

1995 • 263 citations

Heparin Binding to Plasma Proteins, an Important Mechanism for Heparin Resistance

1992 • 255 citations

Thromboprophylaxis with Low Molecular Weight Heparin (Fragmin) in High Risk Pregnancies

1997 • 242 citations

Binding of heparin on the surface of cultured human endothelial cells

1978 • 236 citations

Spontaneous Pneumothorax

1995 • 231 citations

Changes in the pharmacokinetics of the low-molecular-weight heparin enoxaparin sodium during pregnancy

1999 • 223 citations

Case-control study of the frequency of thrombophilic disorders in couples with late foetal loss and no thrombotic antecedent--the Nîmes Obstetricians and Haematologists Study5 (NOHA5).

1999 • 209 citations

Management of the obstetric antiphospholipid syndrome

2004 • 203 citations

Pregnancy complications in women with recurrent miscarriage associated with antiphospholipid antibodies treated with low dose aspirin and heparin

1999 • 201 citations

Safety and efficacy of unfractionated heparin versus enoxaparin in patients who are obese and patients with severe renal impairment: analysis from the ESSENCE and TIMI 11B studies

2003 • 195 citations

The pharmacokinetics and pharmacodynamics of enoxaparin in obese volunteers

2002 • 186 citations

Anticoagulation of Pregnant Women With Mechanical Heart Valves

2003 • 185 citations

Case-control Study of the Frequency of Thrombophilic Disorders in Couples with Late Foetal Loss and no Thrombotic Antecedent

1999 • 173 citations

The effects of long-term heparin therapy during pregnancy on bone density. A prospective matched cohort study.

1996 • 148 citations

Physician Practices in the Treatment of Pulmonary Embolism and Deep Venous Thrombosis

1988 • 131 citations

Low-molecular weight heparin restores in-vitro trophoblast invasiveness and differentiation in presence of immunoglobulin G fractions obtained from patients with antiphospholipid syndrome

1999 • 127 citations

Bone density studies in pregnant women receiving heparin

1996 • 125 citations

The Effects of Long-term Heparin Therapy During Pregnancy on Bone Density

1996 • 124 citations

Bone mineral density during long-term prophylaxis with heparin in pregnancy

1994 • 123 citations

Antithrombotic Therapy for Venous Thromboembolic Disease

1995 • 121 citations

Circulating Procoagulant Microparticles in Women with Unexplained Pregnancy Loss: a New Insight

2001 • 119 citations

Low molecular weight heparin for the treatment of venous thromboembolism in pregnancy: a case series

2002 • 109 citations

Limitations of the Laboratory Monitoring of Heparin Therapy

2002 • 109 citations

Antiphospholipid Syndrome in Pregnancy

2002 • 107 citations

Effect of Patient Weight on the Anticoagulant Response to Adjusted Therapeutic Dosage of Low-Molecular- Weight Heparin for the Treatment ofVenous Thromboembolism

2001 • 104 citations

Dosing in Heavy-weight/Obese Patients with the LMWH, Tinzaparin: A Pharmacodynamic Study

2002 • 104 citations

Antenatal use of enoxaparin for prevention and treatment of thromboembolism in pregnancy

2000 • 104 citations

Absence of Placental Transfer of Pentasaccharide (Fondaparinux, Arixtra®) in the Dually Perfused Human Cotyledon in vitro

2002 • 103 citations

Adjusted versus fixed doses of the low-molecular-weight heparin fragmin in the treatment of deep vein thrombosis. Fragmin-Study Group.

1994 • 100 citations

Is laboratory monitoring of low-molecular-weight heparin therapy necessary? Yes

2004 • 99 citations

Low-molecular-weight heparin for prosthetic heart valves: treatment failure

2000 • 97 citations

6 Hazards of heparin: allergy, heparin-induced thrombocytopenia and osteoporosis

1997 • 94 citations

A pharmacokinetic study of dalteparin (Fragmin??) during late pregnancy

1998 • 93 citations

Hereditary thrombophilia and fetal loss: a prospective follow-up study

2004 • 90 citations

Adjusted Versus Fixed Doses of the Low-Molecular-Weight Heparin Fragmin in the Treatment of Deep Vein Thrombosis

1994 • 87 citations

Bone density changes in pregnant women treated with heparin: a prospective, longitudinal study

1999 • 85 citations

Prevalence of circulating procoagulant microparticles in women with recurrent miscarriage: a case-controlled study

2003 • 80 citations

Low-molecular-weight heparin versus warfarin for secondary prophylaxis of venous thromboembolism: a cost-effectiveness analysis

2001 • 78 citations

Factor Xa Inhibition: Correlation between the Plasma Levels of Anti-Xa Activity and Occurrence of Thrombosis and Haemorrhage

1993 • 78 citations

Clinical management of thrombophilia-related placental vascular complications

2004 • 68 citations

The effect of body weight on dalteparin pharmacokinetics

2000 • 61 citations

Magnetic resonance direct thrombus imaging: a novel technique for imaging venous thromboemboli

2003 • 53 citations

A novel multicolor hybridization scheme applied to localization of a transcribed sequence (D10S170/H4) and deletion mapping in the thyroid cancer cell line TPC-1

1996 • 50 citations

Thromboprophylaxis During Pregnancy, Labour and After Vaginal Delivery

2011 • 48 citations

Fondaparinux: a Factor Xa inhibitor for antithrombotic therapy

2004 • 46 citations

Is laboratory monitoring of low-molecular-weight heparin therapy necessary? No

2004 • 42 citations

Recurrent Pregnancy Loss With Antiphospholipid Antibody

2002 • 40 citations

Thromboembolism in pregnant women with mechanical prosthetic heart valves anticoagulated with low molecular weight heparin

2001 • 34 citations

Pregnancy, Heparin and Osteoporosis

2002 • 32 citations

Thromboprophylaxis with unmonitored intermediate-dose low molecular weight heparin in pregnancies with a previous arterial or venous thrombotic event

2003 • 32 citations

Weight-based administration of dalteparin in obese patients

2003 • 30 citations

Exploring the Role of Low-Molecular-Weight Heparins in Pregnancy

2002 • 30 citations

A complication in anticoagulation using low-molecular weight heparin in a patient with a mechanical valve prosthesis. A case report.

2000 • 27 citations

Duration of therapy for acute venous thromboembolism

2003 • 22 citations

Failure of low molecular-weight heparin in the prevention of prosthetic mitral valve thrombosis during pregnancy: case report and a review of options for anticoagulation.

2002 • 22 citations

Long-term treatment of venous thromboembolism with low-molecular-weight heparin

2000 • 19 citations

Collapse and massive pulmonary edema secondary to thrombosis of a mitral mechanical heart valve prosthesis during low-molecular weight heparin therapy.

1999 • 18 citations

Thromboembolism in pregnant women with mechanical prosthetic heart valves anticoagulated with low molecular weight heparin

2001 • 15 citations

Emergency redo mitral valve replacement in a 27-year-old pregnant female with a clotted prosthetic mitral valve, preoperative fetal demise and postoperative ventricular assist device: a case report

2001 • 14 citations

Deleted Work

1955 • 0 citations