Will Genetics Revolutionize Medicine?

Lifetime and 12-Month Prevalence of DSM-III-R Psychiatric Disorders in the United States

1994 • 12,456 citations

Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results

1995 • 5,291 citations

A novel MHC class I–like gene is mutated in patients with hereditary haemochromatosis

1996 • 3,682 citations

Sick individuals and sick populations

2001 • 3,588 citations

Sick Individuals and Sick Populations

1985 • 2,425 citations

The Risk of Cancer Associated with Specific Mutations ofBRCA1andBRCA2among Ashkenazi Jews

1997 • 2,255 citations

Current estimates from the National Health Interview Survey.

1981 • 1,898 citations

Incidence of Hereditary Nonpolyposis Colorectal Cancer and the Feasibility of Molecular Screening for the Disease

1998 • 1,173 citations

Colorectal Cancer: Molecules and Populations

1999 • 894 citations

Prevalence of BRCA1 and BRCA2 Gene Mutations in Patients With Early-Onset Breast Cancer

1999 • 866 citations

Digenic Retinitis Pigmentosa Due to Mutations at the Unlinked Peripherin/ RDS and ROM1 Loci

1994 • 740 citations

Cancer risk associated with germline DNA mismatch repair gene mutations

1997 • 693 citations

Medical and Ethical Consequences of the Human Genome Project

1991 • 684 citations

Familial colorectal cancer in Ashkenazim due to a hypermutable tract in APC

1997 • 679 citations

High Risk of Cerebral-Vein Thrombosis in Carriers of a Prothrombin-Gene Mutation and in Users of Oral Contraceptives

1998 • 648 citations

Medical and Societal Consequences of the Human Genome Project

1999 • 549 citations

Insights into the functions of BRCA1 and BRCA2

2000 • 335 citations

When can a risk factor be used as a worthwhile screening test?

1999 • 333 citations

Evaluation of a susceptibility gene for schizophrenia on chromosome 6p by multipoint affected sib–pair linkage analysis

1995 • 279 citations

Genetic Testing in Families With Hereditary Nonpolyposis Colon Cancer

1999 • 257 citations

Frequency and Carrier Risk Associated with Common BRCA1 and BRCA2 Mutations in Ashkenazi Jewish Breast Cancer Patients

1998 • 223 citations

The new genetics: Psychological responses to genetic testing

1998 • 220 citations

The new genetics: The new genetics in clinical practice

1998 • 219 citations

Abnormal human haemoglobins. III the chemical difference between normal and sickle cell haemoglobins

1959 • 216 citations

A manic depressive history

1996 • 211 citations

Uptake of cystic fibrosis testing in primary care: supply push or demand pull?

1993 • 198 citations

Apolipoprotein E epsilon4 and incidence of Alzheimer disease in a community population of older persons.

1997 • 174 citations

Offering cystic fibrosis carrier screening to an HMO population: factors associated with utilization.

1994 • 142 citations

Cultural basis for differences between US and French clinical recommendations for women at increased risk of breast and ovarian cancer

1999 • 127 citations

A tale of 3 tails.

1999 • 108 citations

Interpretation of results from genetic studies of multifactorial diseases

1999 • 79 citations

Full-Genome Scan for Linkage in 50 Families Segregating the Bipolar Affective Disease Phenotype

2000 • 76 citations

Impact of genetic testing on causal models of heart disease and arthritis: An analogue study

2000 • 72 citations

Recent advances: Diabetes

1998 • 67 citations

Clinical and molecular studies in full trisomy 22: Further delineation of the phenotype and review of the literature

1995 • 65 citations

Exploring the etiology of Alzheimer disease using molecular genetics

1997 • 58 citations

Response to treatment in hereditary metabolic disease: 1993 survey and 10-year comparison.

1995 • 46 citations

Epidemiologic evaluation of screening for risk factors: application to genetic screening.

1985 • 41 citations

Apolipoprotein E epsilon4 and incidence of Alzheimer disease in a community population of older persons

1997 • 37 citations

Psychiatric genetics: progress, problems, and potential

1999 • 32 citations

Eugenics and Individual Phenotypic Variation: To What Extent Is Biology a Predictive Science?

1998 • 7 citations

Deleted Work

1955 • 0 citations