Regulation of intrasteric inhibition of the multifunctional calcium/calmodulin-dependent protein kinase.

[6] Use of T7 RNA polymerase to direct expression of cloned genes

1990 • 6,681 citations

[19] Rapid and efficient site-specific mutagenesis without phenotypic selection

1987 • 5,413 citations

The Protein Kinase Family: Conserved Features and Deduced Phylogeny of the Catalytic Domains

1988 • 5,115 citations

A bacteriophage T7 RNA polymerase/promoter system for controlled exclusive expression of specific genes.

1985 • 3,185 citations

Solution structure of a calmodulin-target peptide complex by multidimensional NMR

1992 • 1,258 citations

Protein Kinase C Contains a Pseudosubstrate Prototope in Its Regulatory Domain

1987 • 1,020 citations

Structure of a Peptide Inhibitor Bound to the Catalytic Subunit of Cyclic Adenosine Monophosphate-Dependent Protein Kinase

1991 • 949 citations

Calmodulin Trapping by Calcium-Calmodulin-Dependent Protein Kinase

1992 • 644 citations

Molecular cloning of a brain-specific calcium/calmodulin-dependent protein kinase.

1987 • 287 citations

Sequences of autophosphorylation sites in neuronal type II CaM kinase that control Ca2+-independent activity

1988 • 283 citations

Primary Structural Determinants Essential for Potent Inhibition of cAMP-dependent Protein Kinase by Inhibitory Peptides Corresponding to the Active Portion of the Heat-Stable Inhibitor Protein

1989 • 278 citations

cAMP-dependent Protein Kinase

1989 • 274 citations

Calcium/calmodulin-dependent protein kinase II. Characterization of distinct calmodulin binding and inhibitory domains.

1988 • 256 citations

Substrate specificity of a multifunctional calmodulin-dependent protein kinase.

1985 • 243 citations

Inhibitory autophosphorylation of multifunctional Ca2+/calmodulin-dependent protein kinase analyzed by site-directed mutagenesis.

1992 • 220 citations

Functional Analysis of a Complementary DNA for the 50-Kilodalton Subunit of Calmodulin Kinase II

1987 • 179 citations

Regulatory Domain of Calcium/Calmodulin-dependent Protein Kinase II

1989 • 177 citations

Studies of the Regulatory Mechanism of Ca2+/Calmodulin-dependent protein kinase II

1989 • 165 citations

Regulatory interactions of the calmodulin-binding, inhibitory, and autophosphorylation domains of Ca2+/calmodulin-dependent protein kinase II.

1988 • 159 citations

Intrasteric regulation of protein kinases and phosphatases

1991 • 151 citations

Multifunctional Ca2+/calmodulin-dependent protein kinase: domain structure and regulation

1989 • 136 citations

A Novel Ca²⁺/Calmodulin-Dependent Protein Kinase and a Male Germ Cell-Specific Calmodulin-Binding Protein Are Derived from the Same Gene

1991 • 136 citations

Multifunctional calcium/calmodulin-dependent protein kinase made calcium-independent for functional studies

1990 • 127 citations

Rabbit skeletal muscle myosin light chain kinase. The calmodulin binding domain as a potential active site-directed inhibitory domain.

1987 • 122 citations

Structural Basis of the Intrasteric Regulation of Myosin Light Chain Kinases

1992 • 117 citations

Expression of a constitutive form of calcium/calmodulin dependent protein kinase II leads to arrest of the cell cycle in G2.

1992 • 108 citations

The multifunctional Ca2+/calmodulin-dependent protein kinase.

1988 • 99 citations

Active site-directed inhibition of Ca2+/calmodulin-dependent protein kinase type II by a bifunctional calmodulin-binding peptide.

1988 • 94 citations

Expression and characterization of calmodulin-dependent protein kinase II from cloned cDNAs in Chinese hamster ovary cells

1989 • 86 citations

Expression and characterization of the alpha-subunit of Ca2+/calmodulin-dependent protein kinase II using the baculovirus expression system

1990 • 79 citations

Identification of amino acids essential for calmodulin binding and activation of smooth muscle myosin light chain kinase.

1992 • 66 citations

Mutagenesis of Thr-286 in monomeric Ca2+/calmodulin-dependent protein kinase II eliminates Ca2+/calmodulin-independent activity.

1990 • 61 citations

Active catalytic fragment of Ca2+/calmodulin-dependent protein kinase II. Purification, characterization, and structural analysis

1991 • 44 citations

Studies on the regulatory domain of Ca2+/calmodulin-dependent protein kinase II. Functional analyses of arginine 283 using synthetic inhibitory peptides and site-directed mutagenesis of the alpha subunit.

1990 • 31 citations

Studies on the regulatory domain of Ca2+/calmodulin-dependent protein kinase II by expression of mutated cDNAs in Escherichia coli.

1991 • 29 citations

Functional analysis of Ca2+/calmodulin-dependent protein kinase II expressed in bacteria

1989 • 27 citations

Intrasteric regulation of myosin light chain kinase: the pseudosubstrate prototope binds to the active site.

1992 • 21 citations