Systemic mononuclear-cell vasculitis in MRL/Mp-lpr/lpr mice. A histologic and immunocytochemical analysis.

Xenogeneic Monoclonal Antibodies to Mouse Lymphoid Differentiation Antigens*

1979 • 1,989 citations

Spontaneous murine lupus-like syndromes. Clinical and immunopathological manifestations in several strains.

1978 • 1,619 citations

Murine Models of Systemic Lupus Erythematosus

1985 • 1,572 citations

Characterization of the murine T cell surface molecule, designated L3T4, identified by monoclonal antibody GK1.5: similarity of L3T4 to the human Leu-3/T4 molecule.

1983 • 1,307 citations

Mac‐1: a macrophage differentiation antigen identified by monoclonal antibody

1979 • 1,144 citations

EXPERIMENTAL GLOMERULONEPHRITIS

1961 • 730 citations

Monoclonal xenogeneic antibodies to murine cell surface antigens: identification of novel leukocyte differentiation antigens

1978 • 589 citations

A monoclonal antibody discriminating between subsets of T and B cells.

1981 • 565 citations

Mac-2, a novel 32,000 Mr mouse macrophage subpopulation-specific antigen defined by monoclonal antibodies.

1982 • 428 citations

Lymphocytes in the skin of patients with progressive systemic sclerosis

1984 • 369 citations

Identification and initial characterization of a rat monoclonal antibody reactive with the murine interleukin 2 receptor-ligand complex.

1983 • 348 citations

Analysis of T cell function in autoimmune murine strains. Defects in production and responsiveness to interleukin 2.

1981 • 334 citations

The major histocompatibility complex-restricted antigen receptor on T cells. II. Role of the L3T4 product.

1983 • 325 citations

A COMPARATIVE HISTOLOGIC AND IMMUNOLOGIC STUDY IN RABBITS OF INDUCED HYPERSENSITIVITY OF THE SERUM SICKNESS TYPE

1953 • 321 citations

A spontaneous rheumatoid arthritis-like disease in MRL/l mice.

1982 • 303 citations

Abnormalities induced by the mutant gene Ipr: expansion of a unique lymphocyte subset.

1982 • 295 citations

Accessory and stimulating properties of dendritic cells and macrophages isolated from various rat tissues

1982 • 252 citations

Deficient interleukin 2 activity in MRL/Mp and C57BL/6J mice bearing the lpr gene.

1981 • 237 citations

Phenotypic, functional, and molecular genetic comparisons of the abnormal lymphoid cells of C3H-lpr/lpr and C3H-gld/gld mice.

1986 • 224 citations

Identification of ganglio-N-tetraosylceramide as a new cell surface marker for murine natural killer (NK) cells.

1980 • 220 citations

T cells that help B cell responses to soluble antigen are distinguishable from those producing interleukin 2 on mitogenic or allogeneic stimulation.

1986 • 218 citations

Expression and function of interleukin-2 receptors on immature thymocytes

1985 • 217 citations

THE ROLE OF ANTIGEN-ANTIBODY COMPLEXES IN DISEASE.

1963 • 208 citations

Absence of the Lyt-2-,L3T4+ lineage of T cells in mice treated neonatally with anti-I-A correlates with absence of intrathymic I-A-bearing antigen-presenting cell function.

1985 • 191 citations

Distribution of lymphocytes identified by surface markers in murine strains with systemic lupus erythematosus-like syndromes.

1979 • 167 citations

Lymphocyte chemotactic activity of human interleukin 1.

1984 • 165 citations

Sjögren's syndrome in MRL/l and MRL/n mice

1984 • 161 citations

Monoclonal antibody to L3T4 blocks the function of T cells specific for class 2 major histocompatibility complex antigens.

1984 • 140 citations

Differentiation of thymocytes in fetal organ culture: analysis of phenotypic changes accompanying the appearance of cytolytic and interleukin 2-producing cells.

1984 • 131 citations

Influence of thymic genotype on the systemic lupus erythematosus-like disease and T cell proliferation of MRL/Mp-lpr/lpr mice.

1981 • 128 citations

The proliferating cells in autoimmune MRL/lpr mice lack L3T4, an antigen on "helper" T cells that is involved in the response to class II major histocompatibility antigens.

1984 • 128 citations

Analysis of vascular lesions in murine SLE. I. Association with serologic abnormalities.

1983 • 114 citations

Epstein-Barr virus-transformed lymphocytes produce monoclonal autoantibodies that react with antigens in multiple organs

1984 • 112 citations

Association of lpr gene with graft-vs.-host disease-like syndrome.

1985 • 112 citations

Vasculitis in primary vasculitides, granulomatoses, and connective tissue diseases

1983 • 111 citations

The orientation of the nitro substituent predicts the direct-acting bacterial mutagenicity of nitrated polycyclic aromatic hydrocarbons

1985 • 109 citations

Absence of growth by most receptor-expressing fetal thymocytes in the presence of interleukin-2

1985 • 108 citations

Flow cytometry analysis of T cells and continuous T-cell lines from autoimmune MRL/l mice

1981 • 91 citations

A comparative immunologic analysis of several murine strains with autoimmune manifestations

1980 • 90 citations

Immunologic mechanisms in systemic vasculitis.

1976 • 89 citations

Two histopathologic types of inflammatory vascular disease in MRL/Mp autoimmune mice. Model for human vasculitis in connective tissue disease

1985 • 76 citations

Necrotizing vasculitis

1980 • 74 citations

Antigen-specific immunocompetency, B cell function, and regulatory helper and suppressor T cell activities in spontaneously autoimmune mice.

1979 • 64 citations

Autoimmune diseases: immunopathology and etiopathogenesis.

1982 • 61 citations

In vitro correction of the interleukin 2 defect of autoimmune mice

1983 • 60 citations

The role of vascular smooth muscle cells in experimental autoimmune vasculitis. I. The initiation of delayed type hypersensitivity angiitis.

1984 • 52 citations

The cellular basis for immune interferon production in autoimmune MRL-Ipr/Ipr mice.

1983 • 51 citations

Ocular vasculitis in Beh�et's disease

1985 • 48 citations

Studies of lymphoproliferation in MRL-lpr/lpr mice.

1984 • 42 citations

USE OF MONOCLONAL ANTIBODIES TO QUANTITATE T LYMPHOCYTE SUBPOPULATIONS IN HUMAN CARDIAC ALLOGRAFTS

1984 • 36 citations

Intratumoral phenotypic diversity of cloned human lung tumor cell lines and consequences for analyses with monoclonal antibodies

1984 • 35 citations

Comparison of antigen-specific T cell responses in autoimmune MRL/Mp-lpr/lpr and MRL/Mp-+/+ mice.

1984 • 30 citations

Band Keratopathy in MRL/1 and MRL/n Mice

1983 • 30 citations

Immunohistochemical localization of cells reacting with monoclonal antibodies directed against the interleukin-2 receptor of murine, rat and human origin.

1985 • 30 citations

Limiting dilution analysis of interleukin 2 and colony-stimulating factor producer cells in normal and autoimmune mice.

1984 • 28 citations

Defective T cell response to presented antigen in autoimmune mice.

1984 • 28 citations

T cells from autoimmune "IL 2-defective" MRL-lpr/lpr mice continue to grow in vitro and produce IL 2 constitutively.

1984 • 27 citations

Unique surface phenotype of T cells in lymphoproliferative autoimmune MRL/Mp-lpr/lpr mice.

1984 • 24 citations

Experimental autoimmune type of vasculitis resulting from activation of mouse lymphocytes to cultured endothelium.

1983 • 22 citations

The isolation and functional characterization of autoimmune clones expressing inappropriate Ia.

1984 • 20 citations

In Situ Localization of T Lymphocytes in Disseminated Coccidioidomycosis

1985 • 19 citations

Mononuclear-cell pulmonary vasculitis in NZB/W mice. I. Histopathologic evaluation of spontaneously occurring pulmonary infiltrates.

1985 • 18 citations

Mononuclear cell pulmonary vasculitis in NZB/W mice. II. Immunohistochemical characterization of the infiltrating cells.

1986 • 15 citations

T and B Lymphocyte Migration into Syngeneic Tumors

1977 • 14 citations

The pathogenetic basis of animal and human autoimmune disease

1976 • 10 citations

Appearance of T-Cell Subpopulations During the Time Course of Beryllium-Induced Granulomas

1984 • 8 citations

Vasculitis.

1984 • 1 citations