An Animal Behavior Model for Studying the Actions of LSD and Related Hallucinogens

A BIOCHEMICAL AND PHARMACOLOGICAL SUGGESTION ABOUT CERTAIN MENTAL DISORDERS

1954 • 591 citations

Tolerance to and physical dependence on morphine in rats

1963 • 446 citations

Lysergic Acid Diethylamide: Sensitive Neuronal Units in the Midbrain Raphe

1968 • 396 citations

Lysergic acid diethylamide and serotonin: a comparison of effects on serotonergic neurons and neurons receiving a serotonergic input.

1974 • 311 citations

Action of psychotogenic drugs on single midbrain raphe neurons.

1970 • 298 citations

Evidence for a central 5‐hydroxytryptamine receptor stimulation by lysergic acid diethylamide

1968 • 275 citations

A possible correlation between drug-induced hallucinations in man and a behavioural response in mice

1967 • 250 citations

THE DISTRIBUTION AND METABOLISM OF LYSERGIC ACID DIETHYLAMIDE

1957 • 153 citations

Role of 5-Hydroxytryptamine in Mental Diseases and its Antagonism to Lysergic Acid Derivatives

1955 • 149 citations

Cross tolerance between LSD and psilocybin

1961 • 131 citations

Lysergic Acid Diethylamide (LSD-25): I. Physiological and Perceptual Responses

1955 • 124 citations

Studies on lysergic acid diethylamide (LSD-25). I. Effects in former morphine addicts and development of tolerance during chronic intoxication.

1956 • 123 citations

Persistence of lysergic acid diethylamide in the plasma of human subjects

1964 • 118 citations

Studies on Lysergic Acid Diethylamide (LSD-25)

1956 • 109 citations

Mescaline and LSD: Direct and indirect effects on serotonin-containing neurons in brain

1973 • 107 citations

Hallucinogenic drugs of the indolealkylamine type and central monoamine neurons.

1971 • 101 citations

Hallucinogenic indoleamines: Preferential action upon presynaptic serotonin receptors.

1975 • 98 citations

Tolerance and cross-tolerance among psychotomimetic drugs

1968 • 92 citations

Effects of LSD‐25, psilocybin, and psilocin on temporal lobe EEG patterns and learned behavior in the cat

1962 • 78 citations

Screening hallucinogenic drugs: Systematic study of three behavioral tests

1975 • 78 citations

CLINICAL REACTIONS AND TOLERANCE TO LSD IN CHRONIC SCHIZOPHRENIA

1955 • 77 citations

Patterns of Tolerance to Lysergic Acid Diethylamide and Mescaline in Rats

1958 • 76 citations

SOME CENTRAL ACTIONS OF 5‐HYDROXYTRYPTAMINE AND VARIOUS ANTAGONISTS

1956 • 75 citations

Relationships of psychotomimetic to anti-serotonin potencies of congeners of lysergic acid diethylamide (LSD-25)

1959 • 74 citations

Lysergic Acid Diethylamide (LSD-25): XVII. Tolerance Development and its Relationship to a Theory of Psychosis

1956 • 72 citations

Comparative study on the serotonin antagonism of amide derivatives of lysergic acid and of ergot alkaloids.

1958 • 68 citations

[Pharmacological characterization of deseril, a serotonin antagonist].

1960 • 68 citations

Electrophysiological evidence against negative neuronal feedback from the forebrain controlling midbrain raphe unit activity

1977 • 67 citations

TOLERANCE TO BEHAVIORAL EFFECTS OF LSD-25 IN RAT.

1964 • 67 citations

Some New Behaviour-disrupting Amphetamines and their Significance

1967 • 63 citations

Hallucinogenic phenylethylamines: Interactions with serotonin turnover and receptors

1974 • 60 citations

Alterations in the behavioral effects of LSD by pretreatment with p-chlorophenylalanine and ?-methyl-p-tyrosine

1970 • 60 citations

Evidence of catecholamine mediation in the ‘Aberrant’ behaviour induced by lysergic acid diethylamide (LSD) in the rat

1968 • 54 citations

Tolerance to a behavioral effect of lysergic acid diethylamide and cross-tolerance to mescaline in the rat: absence of a metabolic component.

1971 • 53 citations

Some Effects of Bufotenine and Lysergic Acid Diethylamide on the Monkey

1956 • 52 citations

Behavioral and Electroencephalographic Effects of Hallucinogenic Drugs

1956 • 48 citations

Effects of lysergic acid diethylamide (LSD) on habituation and sensitization of the startle response in the rat

1974 • 43 citations

Chemically-induced alterations in the behavioral effects of LSD-25

1964 • 42 citations

Failure of N,N-dimethyltryptamine to evoke tolerance in cats.

1973 • 40 citations

Subjective Reactions to Lysergic Acid Diethylamide (LSD-25)

1962 • 40 citations

Behavioral evidence for the stimulation of CNS serotonin receptors by high doses of LSD.

1976 • 37 citations

2,5-Dimethoxy-4-methylamphetamine (DOM), a neuropharmacological examination.

1972 • 34 citations

Biphasic dose-response effects of N-N-dimethyltryptamine on the rat startle reflex

1974 • 33 citations

Comparison of chlordiazepoxide, methysergide, and cinanserin as modifiers of punished behavior and as antagonists of N,N-dimethyltryptamine.

1972 • 33 citations

PROPHYLAXIS OF FREQUENT VASCULAR HEADACHE WITH METHYSERGIDE*

1962 • 31 citations

LYSERGIC ACID DIETHYLAMIDE ANTAGONISM OF CERTAIN DRUGS

1957 • 31 citations

LSD acts synergistically with serotonin depletion: Evidence from behavioral studies in cats

1976 • 30 citations

Progression of Effects of Lysergic Acid Diethylamide [LSD]

1956 • 28 citations

THE INVESTIGATION OF THE ROLE OF SEROTONIN IN MAMMALIAN BEHAVIOR

1977 • 28 citations

Impairment by lysergic acid diethylamide of accuracy in performance of a delayed alternation test in monkeys

1960 • 27 citations

A Quantifiable Behavioral Correlate of Psychotogen and Tranquilizer Actions

1961 • 22 citations

An experimental study of the participation of the sympathetic nervous system in the lysergic acid diethylamide (LSD) reaction in cats.

1962 • 18 citations

An observational study of hallucinogen-induced behavior in unrestrained Macaca mulatta

1974 • 17 citations

Effect of Lysergic Acid Diethylamide and Bufotenine on Performance of Trained Rats

1959 • 16 citations

THE INFLUENCE OF VARYING DOSAGE ON THE EFFECTS OF LYSERGIC ACID DIETHYLAMIDE (LSD-25) IN HUMANS

1961 • 14 citations

EEG and behavioral effects in animals of some amphetamine derivatives with hallucinogenic properties

1972 • 11 citations

Gross behavioural changes in monkeys following administration of LSD-25, and development of tolerance to LSD-25

1964 • 11 citations

Relationship of the Amygdala to the Mechanism of Action of Two Types of Antidepressants (Thiazenone and Imipramine)

1966 • 10 citations

Some observations on the behavioural effects of hallucinogenic drugs on rats: potentiation by two drugs affecting monoamine metabolism.

1972 • 10 citations

Antagonism of psychotomimetic agents in the conscious cat.

1960 • 5 citations