Validation of an analytical procedure to measure trace amounts of neurosteroids in brain tissue by gas chromatography–mass spectrometry

Neuroactive steroids

1992 • 1,260 citations

Stress-induced elevations of gamma-aminobutyric acid type A receptor-active steroids in the rat brain.

1991 • 943 citations

Handbook of derivatives for chromatography

1978 • 801 citations

Increase in the cerebrospinal fluid content of neurosteroids in patients with unipolar major depression who are receiving fluoxetine or fluvoxamine

1998 • 658 citations

Characterization and measurement of dehydroepiandrosterone sulfate in rat brain.

1981 • 645 citations

Neurosteroids: of the nervous system, by the nervous system, for the nervous system.

1997 • 643 citations

Anxiolytic Effect of Progesterone is Mediated by the Neurosteroid Allopregnanolone at Brain GABA_A Receptors

1995 • 385 citations

Pregnenolone and its sulfate ester in the rat brain

1983 • 382 citations

Neurosteroids: Biosynthesis of Pregnenolone and Progesterone in Primary Cultures of Rat Glial Cells*

1989 • 372 citations

Neurosteroids: 3 alpha-hydroxy-5 alpha-pregnan-20-one and its precursors in the brain, plasma, and steroidogenic glands of male and female rats.

1993 • 344 citations

Relationship between symptom severity and steroid variation in women with premenstrual syndrome: study on serum pregnenolone, pregnenolone sulfate, 5 alpha-pregnane-3,20-dione and 3 alpha-hydroxy-5 alpha-pregnan-20-one.

1996 • 334 citations

Fluoxetine-elicited changes in brain neurosteroid content measured by negative ion mass fragmentography.

1996 • 329 citations

Neurosteroids

1994 • 310 citations

Neurosteroids: oligodendrocyte mitochondria convert cholesterol to pregnenolone.

1987 • 294 citations

Steroid Hormone Regulation of the Brain

1981 • 228 citations

Gas chromatographic-mass fragmentographic quantitation of 3 alpha- hydroxy-5 alpha-pregnan-20-one (allopregnanolone) and its precursors in blood and brain of adrenalectomized and castrated rats

1995 • 169 citations

Astrocytes and neurosteroids: metabolism of pregnenolone and dehydroepiandrosterone. Regulation by cell density.

1993 • 164 citations

Relationship between symptom severity and steroid variation in women with premenstrual syndrome: study on serum pregnenolone, pregnenolone sulfate, 5 alpha-pregnane-3,20-dione and 3 alpha-hydroxy-5 alpha- pregnan-20-one

1996 • 153 citations

Determination of steroid hormones by the use of isotope dilution-mass spectrometry: A definitive method in clinical chemistry

1979 • 135 citations

The regional brain distribution of the neurosteroids pregnenolone and pregnenolone sulfate following intravenous infusion

1997 • 115 citations

Neurosteroids: 3 alpha-hydroxy-5 alpha-pregnan-20-one and its precursors in the brain, plasma, and steroidogenic glands of male and female rats

1993 • 104 citations

Determination of Nonconjugated and Conjugated Steroid Levels in Plasma and Prostate after Separation on C‐18 Columns

1990 • 100 citations

Pregnenolone metabolism in rodent embryonic neurons and astrocytes

1993 • 86 citations

Newer Approaches to the Isolation, Identification, and Quantitation of Steroids in Biological Materials

1982 • 65 citations

0-(2,3,4,5,6-Pentafluorobenzyl)Hydroxylamine Hydrochloride as a Sensitive Derivatizing Agent for the Electron Capture Gas Liquid Chromatographic Analysis of Keto Steroids

1975 • 56 citations

Dehydroepiandrosterone sulfate quantification in serum using high-performance liquid chromatography/ mass spectrometry and a deuterated internal standard: a technique suitable for routine use or as a reference method

1990 • 55 citations

Nano-electrospray tandem mass spectrometry for the analysis of neurosteroid sulphates†

1999 • 51 citations

Neurosteroids in the mouse brain: Behavioral and pharmacological effects of a 3β-hydroxysteroid dehydrogenase inhibitor

1996 • 49 citations

Determination of anabolic steroids by gas chromatography/negative‐ion chemical ionization mass spectrometry and gas chromatography/negative‐ion chemical ionization tandem mass spectrometry with heptafluorobutyric anhydride derivatization

1999 • 29 citations

Analyses for progesterone in serum by gas chromatography/mass spectrometry: target data for external quality assessment of routine assays.

1984 • 25 citations

Dienol heptafluorobutyrates as derivatives for gas liquid chromatography of steroidal Δ4-3-ketones

1973 • 24 citations

Studies on Neurosteroids. VII. Characterization of Pregnenolone, Its Sulfate and Dehydroepiandro-Sterone in Rat Brains Using Liquid Chromatography/Mass Spectrometry

1998 • 24 citations

Determination of anabolic steroids by gas chromatography/negative-ion chemical ionization mass spectrometry and gas chromatography/negative-ion chemical ionization tandem mass spectrometry with heptafluorobutyric anhydride derivatization

1999 • 23 citations

Halogenated Diesters of Testosterone. Response to Electron Capture Detection, Gas Chromatographic and Mass Spectrometric Properties

1972 • 23 citations

Determination of dehydroepiandrosterone sulphate in biological samples by liquid chromatography/atmospheric pressure chemical ionization-mass spectrometry using [7,7,16,16-2H4]-dehydroepiandrosterone sulphate as an internal standard

1998 • 22 citations

GC Behavior of 3-Ketosteroid Methoximes. Application to GC Studies of Adrenocortical Steroid Hormone MO-TMS Derivatives

1972 • 20 citations

Determination of four anabolic steroid metabolites by gas chromatography/mass spectrometry with negative ion chemical ionization and tandem mass spectrometry

1998 • 20 citations

Quantification of steroid conjugates using fast atom bombardment mass spectrometry

1990 • 13 citations

A Neural Mechanism Regulating Follicular Development in the Hamster

1971 • 5 citations