Cracking the cytokine code in psoriasis

A Genome-Wide Association Study Identifies IL23R as an Inflammatory Bowel Disease Gene

2006 • 2,903 citations

Interleukin-22, a TH17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis

2006 • 1,806 citations

A brief history of TH17, the first major revision in the TH1/TH2 hypothesis of T cell–mediated tissue damage

2007 • 1,359 citations

A Large-Scale Genetic Association Study Confirms IL12B and Leads to the Identification of IL23R as Psoriasis-Risk Genes

2007 • 1,070 citations

The IL-23/IL-17 axis in inflammation

2006 • 1,004 citations

IL-23 promotes tumour incidence and growth

2006 • 968 citations

IL‐22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: a potential role in psoriasis

2006 • 898 citations

Increased Expression of Interleukin 23 p19 and p40 in Lesional Skin of Patients with Psoriasis Vulgaris

2004 • 873 citations

IL-22 Inhibits Epidermal Differentiation and Induces Proinflammatory Gene Expression and Migration of Human Keratinocytes

2005 • 817 citations

Stat3 links activated keratinocytes and immunocytes required for development of psoriasis in a novel transgenic mouse model

2004 • 693 citations

Differential Activity of IL-12 and IL-23 in Mucosal and Systemic Innate Immune Pathology

2006 • 664 citations

IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2–dependent mechanisms with implications for psoriasis pathogenesis

2006 • 662 citations

Keratinocytes regain momentum as instigators of cutaneous inflammation

2006 • 59 citations