Cholesterol epoxide is a direct-acting mutagen.

Metabolic epidemiology of colon cancer:Fecal bile acids and neutral sterols in colon cancer patients and patients with adenomatous polyps

1977 • 404 citations

Angiotoxicity of Oxygenated Sterols and Possible Precursors

1980 • 202 citations

Epoxides as products of lipid autoxidation in rat lungs

1979 • 140 citations

Effect of cholesterol metabolites and promoting effect of lithocholic acid in colon carcinogenesis in germ-free and conventional F344 rats.

1979 • 129 citations

Isolation and identification of cholesterol α‐oxide and other minor sterols in human serum

1971 • 121 citations

The HeLa DNA-synthesis inhibition test as a rapid screen for mutagenic carcinogens

1982 • 116 citations

Formation and metabolism in vitro of 5,6-epoxides of cholesterol and β-sitosterol

1974 • 113 citations

Carcinogenic Effects of Steroids

1969 • 101 citations

A model system for the evaluation of the role of cholesterol -oxide in ultraviolet carcinogenesis.

1972 • 97 citations

Transformation of hamster embryo cells by cholesterol-α-epoxide and lithocholic acid

1979 • 94 citations

Studies on glutathione-S-arene oxidase transferase—A sensitive assay and partial purification of the enzyme from sheep liver

1974 • 84 citations

Mutagenic cholesterol preparations

1979 • 81 citations

Cholesterol and cholesterol epoxides in nipple aspirates of human breast fluid.

1981 • 80 citations

Oncogenesis, mutagenesis, DNA damage, and cytotoxicity in cultured mammalian cells treated with alkylating agents.

1979 • 45 citations

DNA synthesis, mutagenesis, DNA damage, and cytotoxicity in cultured mammalian cells treated with alkylating agents.

1980 • 45 citations

CHROMOSOME DAMAGE AND DNA REPAIR INDUCED IN HUMAN FIBROBLASTS BY UV AND CHOLESTEROL OXIDE

1978 • 41 citations

Cholesterol α- and β-epoxides as obligatory intermediates in the hepatic microsomal metabolism of cholesterol to cholestanetriol

1980 • 35 citations

Steroid epoxides in biologic systems: A review

1978 • 34 citations

Lipid epoxide hydrolase in rat lung preparations

1980 • 34 citations

A comparison of the HeLa DNA-synthesis inhibition test and the Ames test for screening of mutagenic carcinogens

1978 • 33 citations

Transformation of hamster embryo cells by neutral sterols and bile acids

1981 • 31 citations

Etiologic Related Studies of Ultraviolet Light-Mediated Carcinogenesis

1976 • 27 citations

Metabolic fate of epoxycholesterol in the rat

1970 • 26 citations

The metabolic fate of cholesterol‐5α,6α‐epoxide in vivo

1979 • 13 citations

Analysis and physiologic significance of cholesterol epoxide in animal tissues

1980 • 13 citations

Metabolism of cholestane-3β,5α,6β-triol. II. Identification of two major neutral metabolites in the rat

1971 • 8 citations

Sterol metabolism in the rat

1981 • 4 citations

Polarographic determination of the reaction rate of the second step in an SN1 displacement

1971 • 2 citations