Comorbidities in Chronic Obstructive Pulmonary Disease

Implications of Recent Clinical Trials for the National Cholesterol Education Program Adult Treatment Panel III Guidelines

2004 • 6,926 citations

C-Reactive Protein, Interleukin 6, and Risk of Developing Type 2 Diabetes Mellitus

2001 • 4,289 citations

The Body-Mass Index, Airflow Obstruction, Dyspnea, and Exercise Capacity Index in Chronic Obstructive Pulmonary Disease

2004 • 3,761 citations

Anemia of Chronic Disease

2005 • 3,522 citations

Comparison of C-Reactive Protein and Low-Density Lipoprotein Cholesterol Levels in the Prediction of First Cardiovascular Events

2002 • 3,483 citations

Salmeterol and Fluticasone Propionate and Survival in Chronic Obstructive Pulmonary Disease

2007 • 3,107 citations

Global Initiative for Chronic Obstructive Lung Disease

2002 • 1,906 citations

Association between chronic obstructive pulmonary disease and systemic inflammation: a systematic review and a meta-analysis

2004 • 1,754 citations

The Epidemiology of Corticosteroid-Induced Osteoporosis: a Meta-analysis

2002 • 1,242 citations

Weight Loss Is a Reversible Factor in the Prognosis of Chronic Obstructive Pulmonary Disease

1998 • 1,085 citations

Long-Term Treatment with Inhaled Budesonide in Persons with Mild Chronic Obstructive Pulmonary Disease Who Continue Smoking

1999 • 1,057 citations

Elevated Levels of Acute-Phase Proteins and Plasminogen Activator Inhibitor-1 Predict the Development of Type 2 Diabetes

2002 • 1,053 citations

Prognostic Value of Nutritional Status in Chronic Obstructive Pulmonary Disease

1999 • 1,023 citations

Trends in the Leading Causes of Death in the United States, 1970-2002

2005 • 997 citations

Mortality in COPD: role of comorbidities

2006 • 949 citations

Quality of Care, Process, and Outcomes in Elderly Patients With Pneumonia

1997 • 898 citations

Impaired lung function and mortality risk in men and women: findings from the Renfrew and Paisley prospective population study

1996 • 897 citations

Cigarette smoking and serum lipid and lipoprotein concentrations: an analysis of published data.

1989 • 862 citations

The Relationship Between Reduced Lung Function and Cardiovascular Mortality

2005 • 854 citations

Effect of Inhaled Triamcinolone on the Decline in Pulmonary Function in Chronic Obstructive Pulmonary Disease

2000 • 816 citations

Timing of Antibiotic Administration and Outcomes for Medicare Patients Hospitalized With Community-Acquired Pneumonia

2004 • 777 citations

Inflammatory Markers and Risk of Developing Type 2 Diabetes in Women

2004 • 777 citations

Hydrocortisone Infusion for Severe Community-acquired Pneumonia

2004 • 696 citations

The Treatment of Unrelated Disorders in Patients with Chronic Medical Diseases

1998 • 629 citations

Mortality After Hospitalization for COPD

2002 • 628 citations

Prospective study of cigarette smoking, alcohol use, and the risk of diabetes in men

1995 • 626 citations

Patterns of Comorbidities in Newly Diagnosed COPD and Asthma in Primary Care

2005 • 608 citations

Cytokines in chronic obstructive pulmonary disease

2001 • 607 citations

Cardiovascular Disease in Patients with Chronic Obstructive Pulmonary Disease, Saskatchewan Canada

2005 • 593 citations

Oxidative capacity of the skeletal muscle and lactic acid kinetics during exercise in normal subjects and in patients with COPD.

1996 • 578 citations

COPD

2002 • 573 citations

Body Mass, Fat-Free Body Mass, and Prognosis in Patients with Chronic Obstructive Pulmonary Disease from a Random Population Sample

2005 • 556 citations

Chronic Obstructive Pulmonary Disease as a Risk Factor for Cardiovascular Morbidity and Mortality

2005 • 537 citations

COPD and Incident Cardiovascular Disease Hospitalizations and Mortality: Kaiser Permanente Medical Care Program

2005 • 524 citations

Raised CRP levels mark metabolic and functional impairment in advanced COPD

2005 • 436 citations

C-reactive protein in patients with COPD, control smokers and non-smokers

2005 • 432 citations

Cardiovascular Morbidity and Mortality in COPD

2005 • 425 citations

The Body Mass Index, Airflow Obstruction, Dyspnea, and Exercise Capacity Index in Chronic Obstructive Pulmonary Disease

2004 • 412 citations

Hyperglycaemia is associated with poor outcomes in patients admitted to hospital with acute exacerbations of chronic obstructive pulmonary disease

2006 • 397 citations

Nutritional status and mortality in chronic obstructive pulmonary disease.

1996 • 394 citations

Co-morbidity contributes to predict mortality of patients with chronic obstructive pulmonary disease

1997 • 390 citations

Comorbidity and Mortality in COPD-Related Hospitalizations in the United States, 1979 to 2001

2005 • 386 citations

Cigarette smoking and diabetes mellitus: evidence of a positive association from a large prospective cohort study

2001 • 372 citations

Comorbid occurrence of laryngeal or pulmonary disease with esophagitis in United States military veterans

1997 • 342 citations

Associated Loss of Fat-free Mass and Bone Mineral Density in Chronic Obstructive Pulmonary Disease

2004 • 339 citations

Low Lung Function and Incident Lung Cancer in the United States

2003 • 324 citations

The Effect of Supplementary Oral Nutrition in Poorly Nourished Patients with Chronic Obstructive Pulmonary Disease

1988 • 314 citations

Relationship between reduced forced expiratory volume in one second and the risk of lung cancer: a systematic review and meta-analysis

2005 • 306 citations

Association between Corticosteroid Use and Vertebral Fractures in Older Men with Chronic Obstructive Pulmonary Disease

1998 • 292 citations

Body Mass, Fat-Free Body Mass, and Prognosis in Patients with Chronic Obstructive Pulmonary Disease from a Random Population Sample: Findings from the Copenhagen City Heart Study

2005 • 289 citations

Pulmonary Embolism in Patients with Unexplained Exacerbation of Chronic Obstructive Pulmonary Disease: Prevalence and Risk Factors

2006 • 286 citations

Influence of training and of inactivity on muscle strength.

1970 • 282 citations

In-Hospital Mortality Following Acute Exacerbations of Chronic Obstructive Pulmonary Disease

2003 • 273 citations

Chronic Obstructive Pulmonary Disease, Asthma, and Risk of Type 2 Diabetes in Women

2004 • 252 citations

A prospective study of cigarette smoking and the incidence of diabetes mellitus among us male physicians

2000 • 247 citations

The Influence of 6 Months of Oral Anabolic Steroids on Body Mass and Respiratory Muscles in Undernourished COPD Patients

1998 • 245 citations

Osteoporosis in lung transplantation candidates with end-stage pulmonary disease

1996 • 241 citations

What do chronic obstructive pulmonary disease patients die from? Amultiple cause coding analysis

2003 • 240 citations

GLOBAL INITIATIVE FOR CHRONIC OBSTRUCTIVE LUNG DISEASE

2018 • 235 citations

Prognostic Value of the Hematocrit in Patients With Severe COPD Receiving Long-term Oxygen Therapy

2005 • 234 citations

Health Care Utilization in Chronic Obstructive Pulmonary Disease

2000 • 230 citations

Oxygen Consumption of the Respiratory Muscles in Normal and in Malnourished Patients with Chronic Obstructive Pulmonary Disease

1989 • 227 citations

The prevalence of osteoporosis in patients with chronic obstructive pulmonary disease—A cross sectional study

2006 • 216 citations

COPD increases the risk of squamous histological subtype in smokers who develop non-small cell lung carcinoma

2004 • 215 citations

Administration of Growth Hormone to Underweight Patients with Chronic Obstructive Pulmonary Disease

1997 • 213 citations

Causes of death in patients with COPD and chronic respiratory failure.

1997 • 211 citations

Anemia and Inflammation in COPD

2005 • 200 citations

Prevalence of comorbidity in patients with a chronic airway obstruction and controls over the age of 40

2001 • 200 citations

Muscle fiber type IIX atrophy is involved in the loss of fat-free mass in chronic obstructive pulmonary disease,,

2002 • 197 citations

Nutritional Status and Lung Function in Patients with Emphysema and Chronic Bronchitis

1983 • 196 citations

Relevance of assessing quadriceps endurance in patients with COPD

2004 • 194 citations

Characterization of Nonresponse to High Caloric Oral Nutritional Therapy in Depleted Patients with Chronic Obstructive Pulmonary Disease

2000 • 192 citations

Systemic inflammation in chronic obstructive pulmonary disease

2003 • 188 citations

Quality of care, process, and outcomes in elderly patients with pneumonia

1997 • 182 citations

Increased Prevalence of Gastroesophageal Reflux Symptoms in Patients With COPD

2001 • 179 citations

Lung function, insulin resistance and incidence of cardiovascular disease: a longitudinal cohort study

2003 • 173 citations

Increased gastro-oesophageal reflux disease in patients with severe COPD

2004 • 166 citations

Physician and patient perceptions in COPD: The COPD Resource Network Needs Assessment Survey

2005 • 157 citations

Inhaled and Nasal Corticosteroid Use and the Risk of Fracture

2003 • 154 citations

Mortality in COPD: The Role of Comorbidities

2011 • 149 citations

Nutritional intervention in malnourished patients with emphysema.

1986 • 144 citations

Death Certificate Reporting of Confirmed Airways Obstructive Disease

1991 • 142 citations

Blood transfusion and lung function in chronically anemic patients with severe chronic obstructive pulmonary disease

1998 • 141 citations

Mortality in COPD patients discharged from hospital: the role of treatment and co-morbidity

2006 • 140 citations

Declining Bone Mass in Men With Chronic Pulmonary Disease

1999 • 138 citations

Pneumonic vs Nonpneumonic Acute Exacerbations of COPD

2002 • 138 citations

Risk of developing diabetes is inversely related to lung function: a population‐based cohort study

2002 • 123 citations

Ventilatory Function and Chronic Mucus Hypersecretion as Predictors of Death from Lung Cancer

1990 • 122 citations

Baseline ventilatory function predicts the development of higher levels of fasting insulin and fasting insulin resistance index: the Normative Aging Study

1998 • 122 citations

Correlates of osteoporosis in chronic obstructive pulmonary disease

2000 • 118 citations

Should pulmonary embolism be suspected in exacerbation of chronic obstructive pulmonary disease?

2006 • 117 citations

Gastroesophageal reflux in patients with asthma and chronic bronchitis.

1987 • 110 citations

Prevalence of anemia in chronic obstructive pulmonary disease: Comparison to other chronic diseases

2005 • 109 citations

SMOKING AND CARDIOVASCULAR DISEASE

2000 • 103 citations

Fracture Risk Associated with Inhaled Corticosteroid Use in Chronic Obstructive Pulmonary Disease

2004 • 102 citations

Prospective Study of Pulmonary Function and Lung Cancer

1991 • 95 citations

Does systemic inflammation trigger local exercise-induced oxidative stress in COPD?

2004 • 94 citations

Blood transfusion facilitating difficult weaning from the ventilator

1998 • 89 citations

Declining FEV1 and chronic productive cough in cigarette smokers: a 25-year prospective study of lung cancer incidence in Tecumseh, Michigan.

1994 • 89 citations

Survival and Cause of Death among Elderly Chronic Obstructive Pulmonary Disease Patients after First Admission to Hospital

1997 • 85 citations

Mechanisms for decreased exercise capacity after bed rest in normal middle-aged men

1983 • 82 citations

Cardiorespiratory deconditioning with static and dynamic leg exercise during bed rest

1976 • 81 citations

Comparison of Bone Mineral Density in Elderly Female Patients With COPD and Bronchial Asthma

2000 • 72 citations

Characteristics of community-acquired pneumonia in patients with chronic obstructive pulmonary disease

2007 • 71 citations

Pulmonary Embolism in Patients with Chronic Obstructive Pulmonary Disease or Congestive Heart Failure

2006 • 70 citations

Anemia, costs and mortality in Chronic Obstructive Pulmonary Disease

2006 • 69 citations

Thomas A. Neff Lecture. Chronic Obstructive Pulmonary Disease: A Systemic Disease

2006 • 62 citations

Recognizing and Treating Glucocorticoid-Induced Osteoporosis in Patients With Pulmonary Diseases

2004 • 60 citations

Comparison of C-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events

2003 • 59 citations

Bone Mineral Density Improvement After Lung Volume Reduction Surgery for Severe Emphysema

2005 • 57 citations

Forced Expiratory Volume (1 Second) and Lung Cancer Incidence and Mortality

1992 • 55 citations

Risk of Myocardial Infarction and Stroke in Smokers Is Related to Plasma Levels of Inflammation-Sensitive Proteins

2004 • 50 citations

Definition, epidemiology, course, and prognosis of COPD

2003 • 46 citations

Impact of comorbidities on the duration of COPD patients' hospital episodes

2003 • 44 citations

Hydrocortisone Infusion for Severe Community-Acquired Pneumonia: A Preliminary Randomized Study

2006 • 44 citations

Helicobacter pylori seroprevalence in patients with chronic obstructive pulmonary disease

2004 • 44 citations

Chronic obstructive pulmonary disease : A systemic disease

2006 • 39 citations

Pulmonary Embolism in Patients with Unexplained Exacerbation of Chronic Obstructive Pulmonary Disease: Prevalence and Risk Factors

2007 • 39 citations

Pulmonary function as a predictor of lung cancer mortality in continuing cigarette smokers and in quitters

2003 • 37 citations

Survival experience of the population needing hospital treatment for asthma or COPD at age 50–54 years

1998 • 36 citations

Prevalence of benign oesophageal disease in the Danish population with special reference to pulmonary disease

1989 • 35 citations

The relationship between stage 1 and 2 non-small cell lung cancer and lung function in men and women

2006 • 19 citations

The prevalence of osteoporosis in patients with chronic obstructive pulmonary disease—a cross sectional study

2006 • 18 citations

Should Pulmonary Embolism be Suspected in Exacerbation of Chronic Obstructive Pulmonary Disease?

2007 • 18 citations

A Comparison of Bone Mineral Density in Elderly Female Patients with COPD and Bronchial Asthma.

2003 • 13 citations

Comorbidities in end-stage lung disease

1999 • 9 citations

Osteoporosis ‐ emerging consensus

1997 • 8 citations