Glial pathology but absence of apoptotic nigral neurons in long‐standing Parkinson's disease

Cell Death: The Significance of Apoptosis

1980 • 7,281 citations

AGEING AND PARKINSON'S DISEASE: SUBSTANTIA NIGRA REGIONAL SELECTIVITY

1991 • 3,275 citations

Reactive microglia are positive for HLA‐DR in the substantia nigra of Parkinson's and Alzheimer's disease brains

1988 • 2,754 citations

MITOCHONDRIAL COMPLEX I DEFICIENCY IN PARKINSON'S DISEASE

1989 • 1,717 citations

Differentiation between cellular apoptosis and necrosis by the combined use of in situ tailing and nick translation techniques.

1994 • 697 citations

Evidence for apoptotic cell death in Huntington disease and excitotoxic animal models

1995 • 604 citations

Cell death in Alzheimer's disease evaluated by DNA fragmentation in situ

1995 • 450 citations

Oxidative damage in neurodegenerative disease

1994 • 428 citations

Complex I Inhibitors Induce Dose‐Dependent Apoptosis in PC12 Cells: Relevance to Parkinson's Disease

1994 • 365 citations

Induction of apoptosis in catecholaminergic PC12 cells by L-DOPA. Implications for the treatment of Parkinson's disease.

1995 • 241 citations

Dopamine induces apoptosis-like cell death in cultured chick sympathetic neurons — A possible novel pathogenetic mechanism in Parkinson's disease

1994 • 222 citations

A Study of Apoptosis in Normal and Pathologic Nervous Tissue After In situ End-Labeling of DNA Strand Breaks

1994 • 205 citations

Surveillance, Intervention and Cytotoxicity: Is There a Protective Role of Microglia?

1994 • 185 citations

Microglial Turnover in the Injured CNS: Activated Microglia Undergo Delayed DNA Fragmentation Following Peripheral Nerve Injury

1995 • 148 citations

Ultrastructural Location of Major Histocompatibility Complex (MHC) Class II Positive Perivascular Cells in Histologically Normal Human Brain

1992 • 148 citations

Is idiopathic parkinsonism the consequence of an event or a process?

1994 • 88 citations