High-Level Gentamicin Resistance in Enterococcus: Microbiology, Genetic Basis, and Epidemiology

Evidence for a chromosome-borne resistance transposon (Tn916) in Streptococcus faecalis that is capable of "conjugal" transfer in the absence of a conjugative plasmid.

1981 • 531 citations

Infectious multiple drug resistance.

1975 • 345 citations

Nucleotide sequence analysis of the gene specifying the bifunctional 6'-aminoglycoside acetyltransferase 2"-aminoglycoside phosphotransferase enzyme in Streptococcus faecalis and identification and cloning of gene regions specifying the two activities

1986 • 305 citations

Plasmids, drug resistance, and gene transfer in the genus Streptococcus

1981 • 279 citations

Plasmid transfer in Streptococcus faecalis: Production of multiple sex pheromones by recipients

1979 • 277 citations

Conjugative Transposons and the Dissemination of Antibiotic Resistance in Streptococci

1986 • 276 citations

Transferable beta-lactamase. A new mechanism for in vitro penicillin resistance in Streptococcus faecalis.

1983 • 256 citations

High-Level Resistance to Gentamicin in Clinical Isolates of Enterococci

1983 • 224 citations

High-level, plasmid-borne resistance to gentamicin in Streptococcus faecalis subsp. zymogenes

1979 • 201 citations

Recovery of resistant enterococci during vancomycin prophylaxis

1988 • 178 citations

Enterococcal Superinfection and Colonization After Therapy with Moxalactam, a New Broad-Spectrum Antibiotic

1981 • 174 citations

High-Level Resistance to Gentamicin in Streptococcus faecalis: Risk Factors and Evidence for Exogenous Acquisition of Infection

1986 • 148 citations

Prevalence of high-level resistance to aminoglycosides in clinical isolates of enterococci.

1970 • 129 citations

High-Level Penicillin Resistance among Isolates of Enterococci

1989 • 123 citations

The Enterococcus: "Putting the Bug in Our Ears"

1987 • 122 citations

Enterococci. Biologic and epidemiologic characteristics and in vitro susceptibility

1982 • 120 citations

Plasmid-mediated resistance to aminocyclitol antibiotics in group D streptococci

1980 • 118 citations

Comparison of two beta-lactamase-producing strains of Streptococcus faecalis

1986 • 106 citations

Aminoglycoside-Inactivating Enzymes in Clinical Isolates of Streptococcus Faecalis

1978 • 102 citations

High-level resistance to gentamicin in clinical isolates of Streptococcus (Enterococcus) faecium

1988 • 102 citations

Purification and characterization of aminoglycoside-modifying enzymes from Staphylococcus aureus and Staphylococcus epidermidis

1984 • 101 citations

Antibiotic-Resistant Flora in Nursing Home Patients Admitted to the Hospital

1985 • 99 citations

In vitro studies of plasmid-mediated penicillinase from Streptococcus faecalis suggest a staphylococcal origin.

1986 • 96 citations

Resistance to Six Aminoglycosidic Aminocyclitol Antibiotics Among Enterococci: Prevalence, Evolution, and Relationship to Synergism with Penicillin

1977 • 94 citations

Enterococcal Infections in Patients Treated with Moxalactam

1982 • 94 citations

Plasmids and pheromone response of the beta-lactamase producer Streptococcus (Enterococcus) faecalis HH22

1988 • 83 citations

High-level aminoglycoside-resistant enterococci. Colonization of nursing home and acute care hospital patients

1987 • 81 citations

Enterococci from Bangkok, Thailand, with high-level resistance to currently available aminoglycosides

1983 • 70 citations

Plasmid-Mediated Mechanisms of Resistance to Aminoglycoside-Aminocyclitol Antibiotics and to Chloramphenicol in Group D Streptococci

1978 • 68 citations

Deoxyribonucleic acid sequence common to staphylococcal and streptococcal plasmids which specify erythromycin resistance

1979 • 67 citations

Effects of medium and inoculum variations on screening for high-level aminoglycoside resistance in Enterococcus faecalis

1988 • 65 citations

High-content aminoglycoside disks for determining aminoglycoside-penicillin synergy against Enterococcus faecalis

1988 • 60 citations

Intergeneric and interspecies gene exchange in gram-positive cocci

1986 • 59 citations

Gentamicin Resistance Plasmids of Enterococci from Diverse Geographic Areas Are Heterogeneous

1988 • 58 citations

Multiply high-level-aminoglycoside-resistant enterococci isolated from patients in a university hospital

1988 • 57 citations

ENTEROCOCCIC INFECTIONS

1943 • 49 citations

Characterization and comparison of two penicillinase-producing strains of Streptococcus (Enterococcus) faecalis

1988 • 49 citations

High-level aminoglycoside resistance in group A, B, G, D (Streptococcus bovis), and viridans streptococci

1982 • 43 citations

Heterogeneity of plasmids determining high-level resistance to gentamicin in clinical isolates of Streptococcus faecalis

1986 • 42 citations

TRANSFERABLE RESISTANCE AND AMINOGLYCOSIDE-MODIFYING ENZYMES IN ENTEROCOCCI

1985 • 41 citations

An investigation of enterococcal bacteremia

1983 • 39 citations

Single-concentration broth microdilution test for detection of high-level aminoglycoside resistance in enterococci

1987 • 36 citations

Plasmid Analysis in the Study of the Epidemiology of Nosocomial Gram-Positive Cocci

1986 • 33 citations

Narrow host range of some streptococcal R plasmids

1982 • 32 citations

Laboratory detection of high-level aminoglycoside-aminocyclitol resistance in Enterococcus spp

1988 • 31 citations

Aortic endocarditis caused by gentamicin-resistantEnterococcus faecalis

1988 • 26 citations

Conjugative R plasmids in Streptococcus faecium (group D)

1982 • 26 citations

Enterococcal Infections: An Increasing Problem in Hospitalized Patients

1988 • 26 citations

The chromosomal 3',5"-aminoglycoside phosphotransferase in Streptococcus pneumoniae is closely related to its plasmid-coded homologs in Streptococcus faecalis and Staphylococcus aureus

1983 • 23 citations

An aminoglycoside disk sensitivity test for use with enterococci

1982 • 23 citations

Aminoglycoside Modification by Gentamicin-Resistant Isolates of Staphylococcus aureus

1978 • 22 citations

Restriction mapping and hybridization studies of a beta-lactamase-encoding fragment from Streptococcus (Enterococcus) faecalis

1988 • 19 citations

Endocarditis Due to Streptococcus faecalis with High-Level Resistance to Gentamicin

1989 • 18 citations

Aminoglycoside-modifying enzyme content of a multiply resistant strain of Streptococcus faecalis

1983 • 17 citations

The enterococcus: High-level resistance to gentamicin and production of beta-lactamase

1988 • 13 citations

Modification of aminoglycoside antibiotics by clinical isolates of Streptococcus faecalis.

1981 • 11 citations

False susceptibility of enterococci to aminoglycosides with blood-enriched Mueller-Hinton agar for disk susceptibility testing

1985 • 7 citations

Cited By (0)

Loading...