Pharmacokinetics, biodistribution and tumor localization of two anti-human B-cell chronic lymphocytic leukemia monoclonal antibodies and their F(ab)′2 fragments in a xenograft model

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Cleavage of structural proteins during the assemble of the head of bacterio-phage T4

1970 • 5,738 citations

Determination of the immunoreactive function of radiolabeled monoclonal antibodies by linear extrapolation to binding at infinite antigen excess

1984 • 923 citations

A simple, non-chromatographic procedure to purify immunoglobulins from serum and ascites fluid

1987 • 624 citations

Chronic Lymphocytic Leukemia: New Insights into Biology and Therapy

1990 • 247 citations

Application of Stepwise Regression to Non-Linear Estimation

1968 • 217 citations

The Nude mouse in experimental and clinical research

1978 • 205 citations

The rapid determination of binding constants for antiviral antibodies by a radioimmunoassay. An analysis of the interaction between hybridoma proteins and influenza virus

1979 • 187 citations

Chronic Lymphocytic Leukemia

1985 • 156 citations

Monoclonal antibodies in cancer detection and therapy

1993 • 150 citations

Biology of the human malignant lymphomasIII. Intracranial heterotransplantation in the nude, athymic mouse

1976 • 122 citations

[65] Determination of the true immunoreactive fraction of monoclonal antibodies after radiolabeling

1986 • 95 citations

Targeting of cancer with radiolabeled antibodies. Prospects for imaging and therapy.

1988 • 77 citations

Limiting factors in the localization of tumours with radiolabelled antibodies

1985 • 69 citations

Application of Stepwise Regression to Non-Linear Estimation

1968 • 66 citations

Biodistribution of monoclonal IgG1, F(ab')2, and Fab' in mice after intravenous injection. Comparison between anti-B cell (anti-Lyb8.2) and irrelevant (MOPC-21) antibodies.

1987 • 57 citations

Interaction of Epstein-Barr virus with leukaemic B cells in vitro. I. Abortive infection and rare cell line establishment from chronic lymphocytic leukaemic cells.

1982 • 56 citations

Comparative localization of murine monoclonal antibody Me1-14 F(ab')2 fragment and whole IgG2a in human glioma xenografts.

1988 • 48 citations

The design of cytotoxic-agent-antibody conjugates.

1987 • 46 citations

Cure of a mouse lymphoma with radio-iodinated antibody

1974 • 44 citations

Transfer of human chronic lymphocytic leukemia to mice with severe combined immune deficiency

1992 • 42 citations

Role of 1q trisomy in tumorigenicity, growth, and metastasis of human leukemic B-cell clones in nude mice.

1990 • 38 citations

Imaging of Human Melanoma Xenografts in Nude Mice With a Radiolabeled Monoclonal Antibody<xref ref-type="fn" rid="FN2">2</xref><xref ref-type="fn" rid="FN3">3</xref>

1982 • 37 citations

Radionuclide imaging of primary renal-cell carcinoma by I-131-labeled antitumor antibody.

1978 • 30 citations

Localization of 131I-labeled antibodies in human renal cell carcinomas and in a mouse hepatoma and correlation with tumor detection by photoscanning.

1980 • 30 citations

Growth and spread in nude mice of Epstein-Barr virus transformed B-cells from a chronic lymphocytic leukemia patient.

1986 • 17 citations

Progression of a human B cell chronic lymphocytic leukemia line in nude mice

1988 • 15 citations

Preclinical pharmacokinetics and localization studies of the radioiodinated anti-ovarian carcinoma MAb MOv18

1991 • 13 citations

Tumor Targeting with Radiolabeled Antibody for Diagnosis and Therapy

1991 • 9 citations

Antigen-binding site protection during radiolabeling leads to a higher immunoreactive fraction.

1991 • 7 citations

The emergence and establishment of a clonal subline with partial duplication of chromosome 1q from a tumorigenic human chronic lymphocytic leukemic B-cell line

1988 • 7 citations

Tumor localization of monoclonal antibodies against human renal carcinoma in a xenograft model

1991 • 5 citations

Monoclonal Antibodies Against Epstein-Barr Virus Transformed B Lymphocytes from a CLL Patient

1990 • 5 citations

Deleted Work

1955 • 0 citations