Short telomeres on human chromosome 17p

Telomeres shorten during ageing of human fibroblasts

1990 • 5,530 citations

A highly conserved repetitive DNA sequence, (TTAGGG)n, present at the telomeres of human chromosomes.

1988 • 2,281 citations

Telomere Shortening and Tumor Formation by Mouse Cells Lacking Telomerase RNA

1997 • 2,086 citations

Chromosome 17 Deletions and p53 Gene Mutations in Colorectal Carcinomas

1989 • 2,081 citations

Telomere reduction in human colorectal carcinoma and with ageing

1990 • 1,672 citations

Evidence for a mitotic clock in human hematopoietic stem cells: loss of telomeric DNA with age.

1994 • 1,133 citations

TELOMERE LENGTH REGULATION

1996 • 1,010 citations

Heterogeneity in telomere length of human chromosomes

1996 • 861 citations

Loss of a yeast telomere: Arrest, recovery, and chromosome loss

1993 • 787 citations

Genetic determination of telomere size in humans: a twin study of three age groups.

1994 • 738 citations

Loss of Heterozygosity in Normal Tissue Adjacent to Breast Carcinomas

1996 • 583 citations

Telomeres in the mouse have large inter-chromosomal variations in the number of T ₂ AG ₃ repeats

1997 • 490 citations

p53 activates expression of HIC-1, a new candidate tumour suppressor gene on 17p13.3

1995 • 426 citations

Telomere dynamics in an immortal human cell line.

1994 • 380 citations

Human telomeres contain at least three types of G–rich repeat distributed non-randomly

1989 • 374 citations

Origin of human chromosome 2: an ancestral telomere-telomere fusion.

1991 • 367 citations

A truncated human chromosome 16 associated with α thalassaemia is stabilized by addition of telomeric repeat (TTAGGG)n

1990 • 288 citations

Human telomeres: fusion and interstitial sites

1989 • 248 citations

Long-term erythropoiesis from constant numbers of CD34+ cells in serum-free cultures initiated with highly purified progenitor cells from human bone marrow.

1992 • 231 citations

Block in Anaphase Chromosome Separation Caused by a Telomerase Template Mutation

1997 • 204 citations

STRUCTURE, FUNCTION, AND REPLICATION OF SACCHAROMYCES CEREVISIAE TELOMERES

1996 • 196 citations

Stringent sequence requirements for the formation of human telomeres.

1994 • 190 citations

Report of the committee on chromosome and gene loss in human neoplasia

1991 • 158 citations

Telomere capture stabilizes chromosome breakage

1993 • 154 citations

Telomere dynamics and genome instability in human cancer

1995 • 129 citations

Evidence for a gene on 17p13.3, distal to TP53, as a target for allele loss in breast tumors without p53 mutations.

1994 • 91 citations

Telomere Length Regulation

1996 • 84 citations

Telomeric structure in cells with chromosome end associations

1993 • 78 citations

High levels of loss at the 17p telomere suggest the close proximity of a tumour suppressor

1996 • 19 citations